291. Hirschsprung disease, entire colon type
13 clinical trials,   32 drugs   (DrugBank: 15 drugs),   0 gene,   0 pathway

Searched query = "Hirschsprung disease, entire colon type", "Hirschsprung disease, small intestine type", "Hirschsprung disease", "Hirschprung disease", "Hirschsprung disease associated entercolitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
No.TrialIDDate_
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1NCT04598841
(ClinicalTrials.gov)
January 1, 202118/10/2020Nutrition Support for Hirschsprung DiseaseA Multicentric Study on Perioperative Nutritional Support for Hirschsprung's DiseaseNutrition Supporting;Hirschsprung Disease;Infants;Prospective StudyDietary Supplement: supplement nutritional supportingTongji HospitalNULLNot yet recruitingN/A2 YearsAll1000NULL
2ChiCTR2000035860
2020-10-012020-08-18Artificial intelligence for pathological grading system of ganglion cells for intraoperative rapid biopsy in Hirschsprung diseaseArtificial intelligence for pathological grading system of ganglion cells for intraoperative rapid biopsy in Hirschsprung disease Hirschsprung diseaseGold Standard:The speciemens and sections will be reveiwed by three senior pediatric gastroenterology pathologists under the novel pathological grading system of ganglion cells in Hirschsprung disease, and the results is regarded as the gold standard.;Index test:Artificial intelligence assisted whole-section patholgic diagnosis system;Xinhua Hospital, Shanghai Jiaotong University School of MedicineNULLPending016BothTarget condition:138;Difficult condition:138China
3NCT04020939
(ClinicalTrials.gov)
March 16, 20202/7/2019The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.Intestinal Atresia;Necrotizing Enterocolitis;Hirschsprung Disease;Gastroschisis;Intestinal Obstruction;Incarcerated Hernia;Intussusception;Malrotation;Volvulus;Meconium Ileus;Intestinal Perforation;TraumaDevice: SPY imaging;Drug: Indocyanine GreenSt. Justine's HospitalNULLRecruitingN/A16 YearsAll35N/ACanada
4NCT03660176
(ClinicalTrials.gov)
January 2, 20194/9/2018Effects of Butyrate Enemas on Postoperative Intestinal Mobility Disorders in Hirschsprung's DiseaseEffects of Butyrate Enemas on Postoperative Intestinal Mobility Disorders in Hirschsprung'sHirschsprung's DiseaseDrug: butyrate enemas + routine management;Other: routine managementAssistance Publique Hopitaux De MarseilleNULLNot yet recruitingN/A17 YearsAll58Phase 3France
5NCT03593252
(ClinicalTrials.gov)
September 1, 201822/5/2018Bowel Preparation in Elective Pediatric Intestinal SurgeryMechanical Bowel Prep and Prophylactic Oral Antibiotic Use in Children: Implications for Intestinal Surgery ComplicationsColostomy Stoma;Ileostomy - Stoma;Jejunostomy Stoma;Hirschprung's Disease;NEC;Inflammatory Bowel Diseases;Meconium Ileus;Bowel ObstructionDrug: Senna;Drug: Sodium Picosulfate, Magnesium Oxide and Citric Acid;Drug: Erythromycin;Drug: Kanamycin;Drug: Cefazolin;Drug: Metronidazole;Other: Nil per osMcMaster UniversityNULLNot yet recruiting6 Months18 YearsAll48N/ANULL
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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6JPRN-UMIN000024993
2016/12/0115/12/2016Study for efficacy of usage of enteral nutrient with immuno-balance modulation action in perioperative management of pediatric patients Hirschsprung's disease, Atresia ani, Congenital biliary dilatation, GERDIn the control group, the following enteral nutrient will be administered (breast milk or artificial milk for infants, Racol for infants).
Dose and duration: Before surgery, the patient will take enteral nutrients at 60 to 100 kcal / kg per day for 3 days. After the surgery, enteral nutrition will restart within 2 to 3 days after surgery, and continue until 6th postoperative day.
In contrast, immunomodulatory nutrition is administered in the test group.
Dose and duration: Before surgery, the patient will take enteral nutrients at 60 to 100 kcal / kg per day for 3 days. After the surgery, enteral nutrition will restart within 2 to 3 days after surgery, and continue until 6th postoperative day.

The study period is from December 1, 2016 to March 31, 2018.
University of Tsukuba HospitalNULLPending6months-old48months-oldMale and Female10Not applicableJapan
7NCT02343562
(ClinicalTrials.gov)
October 20149/1/2015Probiotics for Prophylaxis of Postoperative Hirschsprungs Associated EnterocolitisProbiotics for Prophylaxis of Postoperative Hirschsprungs Associated EnterocolitisHirschsprung DiseaseDietary Supplement: Probiotics;Dietary Supplement: PlaceboCairo UniversityNULLUnknown status6 Months12 YearsAll40Phase 4Egypt
8NCT02234219
(ClinicalTrials.gov)
January 201427/8/2014Comparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung's Disease: A Prospective Multicenter Randomized Controlled TrialComparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung's Disease: A Prospective Multicenter Randomized Controlled TrialConstipationDrug: ProbioticsTongji HospitalNULLRecruitingN/A14 YearsAll50N/AChina
9NCT02350088
(ClinicalTrials.gov)
January 201417/1/2015Fast-track Surgery in the Treatment of Hirschsprung's DiseaseFast-track Surgery in the Treatment of Hirschsprung's DiseaseSurgeryDrug: probiotics;Drug: placeboTongji HospitalChildren's Hospital BostonRecruiting1 Year18 YearsBoth100N/AChina
10NCT02216994
(ClinicalTrials.gov)
January 20136/8/2014A New Scoring System Improves Diagnostic Accuracy of Intestinal Dysganglionosis --a Prospective StudyEfficacy and Accuracy of a New Diagnostic Scoring System to Differentiate Hirschsprung Disease From Hirschsprung Disease Allied Disorders in the Patients With Suspected Intestinal Dysganglinosis: a Prospective StudyHirschsprung DiseaseDrug: high dose lactulose;Behavioral: conservative treatment;Drug: paraffin oilTongji HospitalJiangxi Provincial Children's HospitalRecruitingN/A3 YearsBoth80N/AChina
No.TrialIDDate_
enrollment
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Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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agemin
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PhaseCountries
11NCT01985646
(ClinicalTrials.gov)
October 200931/10/2013A Trial on Conservative Treatment for Infants' Hirschsprung DiseaseA Prospective, Randomized Controlled Trial of Conservative Versus Surgery Treatment of Normal and Short-segment Hirschsprung Disease for InfantsHirschsprung DiseaseProcedure: surgery treatment;Behavioral: anal dilation;Behavioral: colonic lavage;Drug: oral probioticTongji HospitalNULLCompletedN/A3 MonthsBoth48Phase 0NULL
12NCT01934959
(ClinicalTrials.gov)
January 200821/8/2013A Trial on Probiotics in Preventing Hirschsprung's Disease Associated EntercolitisA Prospective Multicenter Randomized Controlled Trial on Probiotics in Preventing Hirschsprung's Disease Associated EntercolitisProbiotics;Hirschsprung's Disease Associated EnterocolitisDrug: BificoTongji HospitalAnhui Provincial HospitalCompleted1 Month13 YearsBoth60Phase 0NULL
13NCT00630838
(ClinicalTrials.gov)
September 200628/2/2008Probiotic Prophylaxis of Hirschprung's Disease Associated Enterocolitis (HAEC)Probiotic Prophylaxis of Hirschprung's Disease Associated Enterocolitis (HAEC)Hirschsprung DiseaseDrug: VSL#3;Drug: PlaceboUniversity of MichiganNULLCompleted1 Month12 MonthsAll62Phase 2United States