329. Aniridia
3 clinical trials,   2 drugs   (DrugBank: 2 drugs),   0 gene,   0 pathway

Searched query = "Aniridia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

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1NCT04117880
(ClinicalTrials.gov)
December 31, 201819/9/2019A Phase 2 Open Label Extension Study in Participants With Nonsense Mutation AniridiaNonsense Mutation Aniridia: An Ataluren (PTC124) Phase 2 Extension StudyAniridiaDrug: AtalurenPTC TherapeuticsNULLWithdrawn2 YearsN/AAll0Phase 2NULL
2NCT02647359
(ClinicalTrials.gov)
January 31, 201629/12/2015Study of Ataluren in Participants With Nonsense Mutation AniridiaSTAR: A Phase 2, Multicenter, Randomized, Double-Masked, Placebo-Controlled Study of the Safety and Efficacy of Ataluren (PTC124) for the Treatment of Nonsense Mutation AniridiaAniridiaDrug: Ataluren;Drug: PlaceboPTC TherapeuticsNULLActive, not recruiting2 YearsN/AAll39Phase 2United States;Canada
3JPRN-UMIN000002948
2013/04/0129/12/2009Cultivated epithelial sheet transplantation for corneal epithelial stem cell deficiency a) Steven's Johnson Syndromeb) Ocular cicatricial pemphigoidc) Chemical/ Thermal Burns of the Cornead) Gelatinous Drop Like Dystrophye) Salzmann Corneal Degenerationf) Congenital AniridiaCorneal epithelial sheet transplantation
Cultivated eptihealial sheet transplantation will be perfored in the surgical department of Keio University Hospital. Simultaneous lamellar keratoplasty will be allowed.
Surgical procedure involves removal of all pannus and abnormal epithelial tissue, the use of 0.04% mitomycin C to prevent fibrosis, and transplantation of the cultivated sheet.
Department of Ophthalmology, Keio University School of MedicineNULLComplete: follow-up complete20years-oldNot applicableMale and Female5Not selectedJapan