78. Hypopituitarism
462 clinical trials,   346 drugs   (DrugBank: 45 drugs),   41 drug target genes,   80 drug target pathways

Searched query = "Hypopituitarism", "Anterior pituitary hypothyroidism", "Syndrome of abnormal secretion of gonadotropin", "Hyposecretion of gonadotropins", "Adrenocorticotropic hormone deficiency", "ACTH deficiency", "Thyroid-stimulating hormone deficiency", "TSH deficiency", "Growth hormone deficiency", "GH deficiency", "GHD", "CGHD", "AGHD", "Prolactin deficiency", "PRL deficiency"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
6 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT00675506
(ClinicalTrials.gov)
July 20087/5/2008Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are ObesePhysiologic Effects of Long-Term GHRH1-44 in Abdominal ObesityAbdominal Obesity;Growth Hormone DeficiencyDrug: Growth hormone releasing hormone (GHRH) 1-44;Drug: PlaceboMassachusetts General HospitalNational Heart, Lung, and Blood Institute (NHLBI)Completed18 Years55 YearsAll60Phase 2United States
2NCT00324064
(ClinicalTrials.gov)
July 20078/5/2006Sexually Dimorphic Effects of GHRH in Adult Growth Hormone TestingSexually Dimorphic Effects of GHRH in Adult Growth Hormone TestingGrowth Hormone DeficiencyProcedure: GHRH/arginine stimulation testingChildren's Mercy Hospital Kansas CityNULLCompleted5 Years40 YearsBoth90N/AUnited States
3NCT00720902
(ClinicalTrials.gov)
February 200716/6/2008Adult Growth Hormone Deficiency and Cardiovascular RiskAssessment of Cardiovascular Risk Markers in GH Deficient Patients With Nonsecreting Pituitary AdenomasGrowth Hormone DeficiencyProcedure: Blood draws;Drug: Growth hormone releasing hormone (GHRH) and arginine;Procedure: Carotid ultrasound;Procedure: MRI;Procedure: Endothelial cell biopsyColumbia UniversityNULLTerminated19 Years65 YearsBoth8N/AUnited States
4EUCTR2004-002125-42-IT
(EUCTR)
22/09/200409/08/2007EFFECT OF PROLONGED TREATMENT WITH TH9507 ON IGF-I LEVELS IN ADOLESCENTS WITH ISOLATED GH DEFICIENCY DUE TO HYPOTHALAMIC PATHOGENESISEFFECT OF PROLONGED TREATMENT WITH TH9507 ON IGF-I LEVELS IN ADOLESCENTS WITH ISOLATED GH DEFICIENCY DUE TO HYPOTHALAMIC PATHOGENESIS EVALUATION OF GROWTH HORMONE RELEASEINN or Proposed INN: SomatorelinAZIENDA SANITARIA OSPEDALIERA S. GIOVANNI BATTISTA DI TORINONULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
Italy
5NCT01060488
(ClinicalTrials.gov)
January 200429/1/2010Comparative Validation of the Growth Hormone Releasing Hormone and Arginine Test for the Diagnosis of Adult Growth Hormone DeficiencyA Phase III, Multicentric, Open-label, Randomised, Comparative, Parallel Group Study of (GHRH + Arginine) Combination Test vs. Insulin Tolerance Test (ITT) in the Diagnosis of Adult Growth Hormone Deficiency (AGHD)Growth Hormone DeficiencyOther: GHRH+Arg, GHRH+Arg, ITT;Other: ITT, ITT, GHRH+Arg.Merck KGaANULLCompleted18 Years60 YearsBoth69Phase 3France
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6NCT03018886
(ClinicalTrials.gov)
May 20016/1/2017Diagnosing Adult Growth Hormone DeficiencyDiagnosis of Adult Growth Hormone Deficiency With Growth Hormone Releasing Hormone Plus Arginine Stimulation TestGrowth Hormone DeficiencyOther: GHRH plus arginine testHelsinki University Central HospitalNULLCompleted16 Years80 YearsAll160N/AFinland