8. Huntington disease
197 clinical trials, 171 drugs (DrugBank: 54 drugs), 82 drug target genes, 144 drug target pathways
Searched query = "Huntington disease", "Huntington chorea"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | EUCTR2009-018123-32-SE (EUCTR) | 30/09/2010 | 10/06/2010 | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease - HORIZON-Plus | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease - HORIZON-Plus | Huntington disease MedDRA version: 12.1;Level: LLT;Classification code 10020469;Term: Huntington's chorea | Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride | Medivation, Inc | NULL | Not Recruiting | Female: yes Male: yes | 350 | United Kingdom;Germany;Netherlands;Denmark;Italy;Sweden | |||
| 2 | EUCTR2009-018123-32-NL (EUCTR) | 23/08/2010 | 14/04/2010 | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease - HORIZON-Plus | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease - HORIZON-Plus | Huntington disease MedDRA version: 12.1;Level: LLT;Classification code 10020469;Term: Huntington's chorea | Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride | Medivation, Inc | NULL | Not Recruiting | Female: yes Male: yes | 350 | United Kingdom;Germany;Netherlands;Denmark;Italy;Sweden | |||
| 3 | EUCTR2009-018123-32-IT (EUCTR) | 28/07/2010 | 15/07/2010 | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease(Protocol DIM20EXT) - Horizon-Plus | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease(Protocol DIM20EXT) - Horizon-Plus | Huntington`s Corea MedDRA version: 9.1;Level: LLT;Classification code 10020469 | Product Name: Dimebon INN or Proposed INN: Dimebon dihydrochloride Product Name: Dimebon INN or Proposed INN: Dimebon dihydrochloride | MEDIVATION, INC. | NULL | Not Recruiting | Female: yes Male: yes | 350 | United Kingdom;Germany;Netherlands;Denmark;Italy;Sweden | |||
| 4 | EUCTR2009-018123-32-DE (EUCTR) | 07/06/2010 | 02/03/2010 | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease - HORIZON-Plus | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease - HORIZON-Plus | Huntington disease MedDRA version: 12.1;Level: LLT;Classification code 10020469;Term: Huntington's chorea | Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride | Medivation, Inc | NULL | Not Recruiting | Female: yes Male: yes | 350 | Denmark;Netherlands;Germany;Italy;United Kingdom;Sweden | |||
| 5 | EUCTR2009-018123-32-GB (EUCTR) | 14/05/2010 | 18/03/2010 | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease - HORIZON-Plus | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease - HORIZON-Plus | Huntington disease MedDRA version: 12.1;Level: LLT;Classification code 10020469;Term: Huntington's chorea | Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride | Medivation, Inc | NULL | Not Recruiting | Female: yes Male: yes | 350 | Germany;United Kingdom;Netherlands;Denmark;Italy;Sweden | |||
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 6 | EUCTR2009-018123-32-DK (EUCTR) | 23/04/2010 | 16/03/2010 | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease - HORIZON-Plus | HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimebon (Latrepirdine) in Subjects with Huntington Disease - HORIZON-Plus | Huntington disease MedDRA version: 12.1;Level: LLT;Classification code 10020469;Term: Huntington's chorea | Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride | Medivation, Inc | NULL | Not Recruiting | Female: yes Male: yes | 350 | United Kingdom;Germany;Netherlands;Denmark;Italy;Sweden | |||
| 7 | EUCTR2009-011800-44-NL (EUCTR) | 20/01/2010 | 28/09/2009 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease - HORIZON | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease - HORIZON | Huntington disease MedDRA version: 9.1;Level: LLT;Classification code 10020469;Term: Huntington's chorea | Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride | Medivation, Inc | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Germany;United Kingdom;Netherlands;Denmark;Italy;Sweden | ||
| 8 | EUCTR2009-011800-44-IT (EUCTR) | 22/12/2009 | 04/11/2009 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease Version 2.0 08 May 2009 - DIM20 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease Version 2.0 08 May 2009 - DIM20 | Patients with Mild-to-Moderate Huntington Disease MedDRA version: 12.1;Level: LLT;Classification code 10020469;Term: Huntington's chorea | Product Name: Dimebon Product Name: Dimebon INN or Proposed INN: Dimebon dihydrochloride | MEDIVATION, INC. | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Germany;United Kingdom;Netherlands;Denmark;Italy;Sweden | ||
| 9 | EUCTR2009-011800-44-SE (EUCTR) | 14/12/2009 | 23/09/2009 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease - HORIZON | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease - HORIZON | Huntington disease MedDRA version: 9.1;Level: LLT;Classification code 10020469;Term: Huntington's chorea | Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride | Medivation, Inc | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Germany;United Kingdom;Netherlands;Denmark;Italy;Sweden | ||
| 10 | EUCTR2009-011800-44-GB (EUCTR) | 07/10/2009 | 05/06/2009 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease - HORIZON | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease - HORIZON | Huntington disease MedDRA version: 9.1;Level: LLT;Classification code 10020469;Term: Huntington's chorea | Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride | Medivation, Inc | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Germany;United Kingdom;Netherlands;Denmark;Italy;Sweden | ||
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 11 | EUCTR2009-011800-44-DE (EUCTR) | 07/10/2009 | 06/07/2009 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease - HORIZON | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease - HORIZON | Huntington disease MedDRA version: 9.1;Level: LLT;Classification code 10020469;Term: Huntington's chorea | Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride | Medivation, Inc | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Denmark;Netherlands;Germany;Italy;United Kingdom;Sweden | ||
| 12 | EUCTR2009-011800-44-DK (EUCTR) | 11/09/2009 | 04/08/2009 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease - HORIZON | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Dimebon in Patients with Mild-to-Moderate Huntington Disease - HORIZON | Huntington disease MedDRA version: 9.1;Level: LLT;Classification code 10020469;Term: Huntington's chorea | Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descriptive name: Dimebon dihydrochloride | Medivation, Inc | NULL | Not Recruiting | Female: yes Male: yes | 350 | Phase 3 | Germany;United Kingdom;Netherlands;Denmark;Italy;Sweden |