DDrare: Database of Drug Development for Rare Diseases

Trametinib tablet (DrugBank: Trametinib)

4 diseases

ID	Disease name (Link within this page)	Number of trials
2	Amyotrophic lateral sclerosis	0
34	Neurofibromatosis	0
279	Huge venous malformation with cervical, oral and pharyngeal diffuse lesion	1
280	Huge arteriovenous malformation with cervicofacial or limb lesion	0

2. Amyotrophic lateral sclerosis [ 508 clinical trials, 530 drugs, (DrugBank: 146 drugs), 170 drug target genes, 221 drug target pathways]

Searched query = "Amyotrophic lateral sclerosis", "ALS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 508 trial found

34. Neurofibromatosis [ 120 clinical trials, 182 drugs, (DrugBank: 72 drugs), 84 drug target genes, 194 drug target pathways]

Searched query = "Neurofibromatosis", "NF1", "von Recklinghausen disease", "NF2"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 120 trial found

279. Huge venous malformation with cervical, oral and pharyngeal diffuse lesion [ 12 clinical trials, 23 drugs, (DrugBank: 9 drugs), 3 drug target genes, 103 drug target pathways]

Searched query = "Huge venous malformation with cervical, oral and pharyngeal diffuse lesion", "Huge venous malformation", "Venous malformation"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 12 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04258046 (ClinicalTrials.gov)	March 31, 2020	16/1/2020	Trametinib in the Treatment of Complicated Extracranial Arterial Venous Malformation	Phase II Clinical Trial of MEK Inhibitor Trametinib in the Treatment of Complicated Extracranial Arterial Venous Malformation (VM)	Venous Malformation;Arterial Disease	Drug: Trametinib tablet	Stanford University	Boston Children's Hospital	Not yet recruiting	12 Years	60 Years	All	30	Phase 2	United States

280. Huge arteriovenous malformation with cervicofacial or limb lesion [ 22 clinical trials, 26 drugs, (DrugBank: 13 drugs), 11 drug target genes, 147 drug target pathways]

Searched query = "Huge arteriovenous malformation with cervicofacial or limb lesion", "Huge arteriovenous malformation", "Arteriovenous malformation"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 22 trial found