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24 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  68ga-neb  [3] 46, 89, 280 💬 
 2  Bevacizumab  Bevacizumab  [1] D06409 💬  [1] VEGFA 💬  [22] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway  [9] 13, 34, 85, 86, 87, 89, 227, 280, 331 💬 
 3  Bleomycin  Bleomycin  [3] D02177, D03229, D07535 💬  [4] 96, 278, 279, 280 💬 
 4  Dexmedetomidine  Dexmedetomidine  [2] D00514, D01205 💬  [3] ADRA2A, ADRA2B, ADRA2C 💬  [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [12]  2 ,  4 ,  6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬 
 5  Dexmedetomidine 1  Dexmedetomidine  [2] D00514, D01205 💬  [3] ADRA2A, ADRA2B, ADRA2C 💬  [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [1] 280 💬 
 6  Dexmedetomidine 2  Dexmedetomidine  [2] D00514, D01205 💬  [3] ADRA2A, ADRA2B, ADRA2C 💬  [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [1] 280 💬 
 7  Dexmedetomidine 3  Dexmedetomidine  [2] D00514, D01205 💬  [3] ADRA2A, ADRA2B, ADRA2C 💬  [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [1] 280 💬 
 8  Doxycycline  Doxycycline  [5] D00307, D02129, D03903, D03904, D07876 💬  [15] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 162, 167, 227, 280, 299 💬 
 9  Ethanol  Ethanol  [4] D00068, D02798, D04855, D06542 💬  [4] 51, 97, 279, 280 💬 
 10  Heparin  Heparin  [1] D07510 💬  [1] SERPINC1 💬  [1] Complement and coagulation cascades  [11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬 
 11  Heparin sodium  Heparin  [1] D07510 💬  [1] SERPINC1 💬  [1] Complement and coagulation cascades  [2] 280, 299 💬 
 12  L04aa10  [2] 278, 280 💬 
 13  Lipiodol  [1] 280 💬 
 14  Lipiodol® ultra fluid with surgical glues  [1] 280 💬 
 15  Lovastatin  Lovastatin  [1] D00359 💬  [1] HMGCR 💬  [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis  [11]  6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 
 16  Mekinist  [2] 34, 280 💬 
 17  Minocycline  Minocycline  [2] D00850, D05045 💬  [13]  2 ,  6 ,  8 , 13, 46, 85, 90, 94, 162, 201, 206, 280, 299 💬 
 18  Other: normal saline  [4] 13, 222, 226, 280 💬 
 19  Rapamune  [8]  2 , 60, 66, 67, 84, 158, 278, 280 💬 
 20  Sirolimus  Sirolimus  [1] D00753 💬  [1] MTOR 💬  [50] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway  [35]  6 , 13, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 89, 98, 127, 137, 157, 158, 192, 222, 277, 278, 279, 280, 281, 283, 285, 331 💬 
 21  Sirolimus 0,1% crème  Sirolimus  [1] D00753 💬  [1] MTOR 💬  [50] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway  [2] 278, 280 💬 
 22  Sirolimus 1mg/ml  Sirolimus  [1] D00753 💬  [1] MTOR 💬  [50] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway  [2] 278, 280 💬 
 23  Sufentanil  Sufentanil  [2] D00845, D05938 💬  [1] OPRM1 💬  [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [2] 70, 280 💬 
 24  Thalidomide  Thalidomide  [1] D00754 💬  [1] TNF 💬  [65] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway  [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 

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