DDrare: Database of Drug Development for Rare Diseases

Pioglitazone and tretinoin (DrugBank: Tretinoin, Pioglitazone)

5 diseases

ID	Disease name (Link within this page)	Number of trials
2	Amyotrophic lateral sclerosis	1
63	Idiopathic thrombocytopenic purpura	0
75	Cushing disease	0
94	Primary sclerosing cholangitis	0
231	Alpha-1-antitrypsin deficiency	0

2. Amyotrophic lateral sclerosis [ 508 clinical trials, 530 drugs, (DrugBank: 146 drugs), 170 drug target genes, 221 drug target pathways]

Searched query = "Amyotrophic lateral sclerosis", "ALS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 508 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00919555 (ClinicalTrials.gov)	June 2008	8/6/2009	Combination Therapy in Amyotrophic Lateral Sclerosis (ALS)	Phase IIA Trial: Tretinoin and Pioglitazone HCL Combination Therapy in Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	Drug: Pioglitazone and Tretinoin;Drug: Tretinoin and Pioglitazone HCL;Drug: Placebo	Phoenix Neurological Associates, LTD	NULL	Completed	18 Years	85 Years	Both	28	Phase 1;Phase 2	United States

63. Idiopathic thrombocytopenic purpura [ 311 clinical trials, 185 drugs, (DrugBank: 39 drugs), 43 drug target genes, 132 drug target pathways]

Searched query = "Idiopathic thrombocytopenic purpura", "Primary immune thrombocytopenia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 311 trial found

75. Cushing disease [ 191 clinical trials, 172 drugs, (DrugBank: 48 drugs), 61 drug target genes, 121 drug target pathways]

Searched query = "Cushing disease", "Cushing"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 191 trial found

94. Primary sclerosing cholangitis [ 134 clinical trials, 105 drugs, (DrugBank: 37 drugs), 18 drug target genes, 131 drug target pathways]

Searched query = "Primary sclerosing cholangitis", "PSC"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 134 trial found

231. Alpha-1-antitrypsin deficiency [ 83 clinical trials, 89 drugs, (DrugBank: 16 drugs), 35 drug target genes, 46 drug target pathways]

Searched query = "Alpha-1-antitrypsin deficiency", "AATD"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 83 trial found