DDrare: Database of Drug Development for Rare Diseases

Doxycycline hyclate (DrugBank: Doxycycline)

3 diseases

ID	Disease name (Link within this page)	Number of trials
23	Prion disease	1
96	Crohn disease	0
227	Osler disease	1

23. Prion disease [ 4 clinical trials, 5 drugs, (DrugBank: 2 drugs), 0 drug target gene, 0 drug target pathway]

Searched query = "Prion disease", "Creutzfeldt-Jakob disease", "CJD", "Gerstmann-Straussler-Scheinker syndrome", "Fatal familial insomnia", "Kuru disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 4 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2010-022233-28-IT (EUCTR)	20/06/2011	05/03/2012		Fatal familial insomnia: preventive treatment with doxycycline of at risk individuals - Doxycycline in FFI individuals	Subjects born between 1958 and 1969 belonging to the Treviso FFI family, tested previously for Prion D178N/129M mutation MedDRA version: 14.1;Level: SOC;Classification code 10029205;Term: Nervous system disorders;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Trade Name: BASSADO INN or Proposed INN: DOXYCYCLINE HYCLATE	IST. DI RICERCHE FARMACOLOG. M. NEGRI	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Italy

96. Crohn disease [ 2,209 clinical trials, 1,276 drugs, (DrugBank: 240 drugs), 166 drug target genes, 210 drug target pathways]

Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 2,209 trial found

227. Osler disease [ 49 clinical trials, 69 drugs, (DrugBank: 21 drugs), 23 drug target genes, 132 drug target pathways]

Searched query = "Osler disease", "Hereditary hemorrhagic telangiectasia", "Osler-Weber-Rendu disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 49 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03397004 (ClinicalTrials.gov)	September 12, 2018	21/11/2017	Doxycycline for Hereditary Hemorrhagic Telangiectasia	Doxycycline Crossover Trial for Hereditary Hemorrhagic Telangiectasia	Hereditary Hemorrhagic Telangiectasia (HHT)	Drug: Doxycycline Hyclate;Drug: Placebo	St. Michael's Hospital, Toronto	Barrow Neurological Institute;Duke University;Feinstein Institute for Medical Research;University of Pittsburgh;Sunnybrook Health Sciences Centre	Recruiting	18 Years	N/A	All	30	Phase 2	Canada