DDrare: Database of Drug Development for Rare Diseases

Dupilumab (blinded) (DrugBank: Dupilumab)

4 diseases

ID	Disease name (Link within this page)	Number of trials
51	Scleroderma	0
98	Eosinophilic gastrointestinal disease	1
160	Congenital ichthyosis	0
162	Pemphigoid	0

51. Scleroderma [ 466 clinical trials, 536 drugs, (DrugBank: 142 drugs), 110 drug target genes, 210 drug target pathways]

Searched query = "Scleroderma", "Systemic sclerosis", "SSc", "dcSSc", "lcSSc"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 466 trial found

98. Eosinophilic gastrointestinal disease [ 128 clinical trials, 147 drugs, (DrugBank: 40 drugs), 34 drug target genes, 132 drug target pathways]

Searched query = "Eosinophilic gastrointestinal disease", "Eosinophilic gastroenteritis", "Eosinophilic esophagitis", "Eosinophilic colitis", "Eosinophilic gastro-intestinal disorder", "EGID", "Neonatal food-protein induced enterocolitis", "N-FPIES"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 128 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03678545 (ClinicalTrials.gov)	September 1, 2020	6/8/2018	Dupilumab in Eosinophilic Gastritis	A Randomized, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy of Dupilumab (Anti-IL4a) in Subjects With Eosinophilic Gastritis	Eosinophilic Gastritis;Eosinophilic Gastroenteritis	Drug: Dupilumab (blinded);Drug: Placebo (blinded);Drug: Dupilumab (open-label)	Children's Hospital Medical Center, Cincinnati	Regeneron Pharmaceuticals	Not yet recruiting	12 Years	70 Years	All	40	Phase 2	United States

160. Congenital ichthyosis [ 32 clinical trials, 62 drugs, (DrugBank: 18 drugs), 15 drug target genes, 107 drug target pathways]

Searched query = "Congenital ichthyosis", "Keratinopathic ichthyosis", "Epidermolytic ichthyosis", "Harlequin ichthyosis", "Congenital Ichthyosiform Erythroderma", "Foliate ichthyosis", "Ichthyosis syndrome", "Netherton syndrome", "Sjogren-Larsson syndrome", "Sjögren-Larsson syndrome", "Keratitis-ichtyosis-deafness syndrome", "Dorfman-Chanarin syndrome", "Neutral lipid storage disease", "NLSD", "Multiple sulfatase deficiency", "Austin disease", "Recessive X-linked ichthyosis", "RXLI", "X-linked recessive ichthyosis", "Ichthyosis, brittle hair, impaired intelligence, decreased fertility and short stature", "IBID", "Trichothiodystrophy", "Follicular ichthyosis", "Congenital hemidysplasia, ichthyosiform erythroderma or nevus, and limb defects syndrome", "CHILD syndrome", "Conradi-Hunermann-Happle syndrome", "Conradi-Hünermann-Happle syndrome", "CHHS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 32 trial found

162. Pemphigoid [ 70 clinical trials, 117 drugs, (DrugBank: 46 drugs), 30 drug target genes, 128 drug target pathways]

Searched query = "Pemphigoid", "Epidermolysis bullosa acquisita"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 70 trial found