DDrare: Database of Drug Development for Rare Diseases

Carbon monoxide (DrugBank: Carbon, Carbon monoxide)

7 diseases

ID	Disease name (Link within this page)	Number of trials
6	Parkinson disease	0
13	Multiple sclerosis/Neuromyelitis optica	0
53	Sjogren syndrome	0
70	Spinal stenosis	0
85	Idiopathic interstitial pneumonia	1
86	Pulmonary arterial hypertension	1
298	Hereditary pancreatitis	1

6. Parkinson disease [ 2,123 clinical trials, 2,046 drugs, (DrugBank: 324 drugs), 183 drug target genes, 198 drug target pathways]

Searched query = "Parkinson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 2,123 trial found

13. Multiple sclerosis/Neuromyelitis optica [ 3,050 clinical trials, 2,147 drugs, (DrugBank: 348 drugs), 244 drug target genes, 228 drug target pathways]

Searched query = "Multiple sclerosis/Neuromyelitis optica", "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 3,050 trial found

53. Sjogren syndrome [ 234 clinical trials, 270 drugs, (DrugBank: 85 drugs), 49 drug target genes, 174 drug target pathways]

Searched query = "Sjogren syndrome", "Sjögren syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 234 trial found

70. Spinal stenosis [ 91 clinical trials, 195 drugs, (DrugBank: 54 drugs), 60 drug target genes, 85 drug target pathways]

Searched query = "Spinal stenosis", "Extensive spinal canal stenosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 91 trial found

85. Idiopathic interstitial pneumonia [ 514 clinical trials, 377 drugs, (DrugBank: 108 drugs), 97 drug target genes, 204 drug target pathways]

Searched query = "Idiopathic interstitial pneumonia", "IIPs", "Idiopathic pulmonary fibrosis", "IPF", "Usual interstitial pneumonia", "UIP", "Non-specific interstitial pneumonia", "NSIP", "Acute interstitial pneumonia", "AIP", "Diffuse alveolar damage", "DAD", "COP", "Organizing pneumonia", "OP", "Desquamative interstitial pneumonia", "DIP", "Respiratory bronchiolitis - associated interstitial lung disease", "RB-ILD", "Lymphocytic interstitial pneumonia", "LIP"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 514 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01214187 (ClinicalTrials.gov)	July 2011	30/9/2010	Study of Inhaled Carbon Monoxide to Treat Idiopathic Pulmonary Fibrosis	Phase II Study of Inhaled CO for the Treatment of Idiopathic Pulmonary Fibrosis	Idiopathic Pulmonary Fibrosis	Drug: inhaled carbon monoxide;Other: Oxygen	Brigham and Women's Hospital	National Heart, Lung, and Blood Institute (NHLBI);University of California, San Francisco;University of Chicago;University of Illinois at Chicago;University of Michigan;Columbia University;Tulane University;University of Washington	Completed	18 Years	85 Years	All	58	Phase 2	United States

86. Pulmonary arterial hypertension [ 1,083 clinical trials, 667 drugs, (DrugBank: 122 drugs), 98 drug target genes, 185 drug target pathways]

Searched query = "Pulmonary arterial hypertension", "PAH", "IPAH", "HPAH", "Eisenmenger syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 1,083 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01523548 (ClinicalTrials.gov)	July 2012	27/1/2012	Carbon Monoxide Therapy for Severe Pulmonary Arterial Hypertension	Carbon Monoxide Therapy for Severe Pulmonary Arterial Hypertension	Hypertension, Pulmonary	Drug: Carbon Monoxide	University of Illinois at Chicago	National Institutes of Health (NIH);National Heart, Lung, and Blood Institute (NHLBI)	Withdrawn	18 Years	N/A	All	0	Phase 1;Phase 2	United States

298. Hereditary pancreatitis [ 93 clinical trials, 168 drugs, (DrugBank: 51 drugs), 48 drug target genes, 134 drug target pathways]

Searched query = "Hereditary pancreatitis", "Chronic pancreatitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 93 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02567240 (ClinicalTrials.gov)	January 2015	1/10/2015	Carbon Monoxide-Saturated Medium for Islet Isolation	A Novel Approach to Harvest Islets for Autologous Islet Transplantation	Chronic Pancreatitis	Other: Carbon monoxide-bubbled mediums	Medical University of South Carolina	NULL	Completed	18 Years	69 Years	All	16	Phase 1;Phase 2	United States