Isis 443139 10 mg    (DrugBank: -)

1 disease
IDDisease name (Link within this page)Number of trials
8Huntington disease1

8. Huntington disease    [ 197 clinical trials,   171 drugs,   (DrugBank: 54 drugs),   82 drug target genes,   144 drug target pathways]
Searched query = "Huntington disease", "Huntington chorea"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 197 trial found
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PhaseCountries
1NCT02519036
(ClinicalTrials.gov)
August 6, 20151/8/2015Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 443139 in Participants With Early Manifest Huntington's DiseaseA Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses of Intrathecally Administered ISIS 443139 in Patients With Early Manifest Huntington's DiseaseHuntington's DiseaseDrug: ISIS 443139 10 mg;Drug: ISIS 443139 30 mg;Drug: ISIS 443139 60 mg;Drug: ISIS 443139 90 mg;Drug: ISIS 443139 120 mg;Other: PlaceboIonis Pharmaceuticals, Inc.NULLCompleted25 Years65 YearsAll46Phase 1;Phase 2Canada;Germany;United Kingdom