DDrare: Database of Drug Development for Rare Diseases

Choline supplementation (DrugBank: Choline)

4 diseases

ID	Disease name (Link within this page)	Number of trials
93	Primary biliary cholangitis [Primary biliary cirrhosis (~Mar 2017)]	0
171	Wilson disease	0
193	Prader-Willi syndrome	0
299	Cystic fibrosis	1

93. Primary biliary cholangitis [Primary biliary cirrhosis (~Mar 2017)] [ 230 clinical trials, 215 drugs, (DrugBank: 51 drugs), 34 drug target genes, 107 drug target pathways]

Searched query = "Primary biliary cholangitis", "Primary biliary cirrhosis", "PBC"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 230 trial found

171. Wilson disease [ 50 clinical trials, 59 drugs, (DrugBank: 17 drugs), 3 drug target genes, 28 drug target pathways]

Searched query = "Wilson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 50 trial found

193. Prader-Willi syndrome [ 95 clinical trials, 104 drugs, (DrugBank: 27 drugs), 50 drug target genes, 63 drug target pathways]

Searched query = "Prader-Willi syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 95 trial found

299. Cystic fibrosis [ 1,592 clinical trials, 1,539 drugs, (DrugBank: 255 drugs), 81 drug target genes, 162 drug target pathways]

Searched query = "Cystic fibrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 1,592 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00686361 (ClinicalTrials.gov)	October 2007	26/5/2008	Choline Nutrition in Children With Cystic Fibrosis (CF)	To Investigate Whether Choline Supplementation in Children With CF Will Correct Biochemical Markers of Choline Deficiency and Improve Plasma Indices of Methylation Capacity and Redox Status and Result in Decreased Pro-inflammatory Cytokines	Cystic Fibrosis	Drug: Choline supplementation	University of British Columbia	Cystic Fibrosis Foundation Therapeutics	Completed	5 Years	17 Years	Both	34	N/A	Canada