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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Acetate1件: Acetate---43件: 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
2ADVATE1件: Antihemophilic factor, human recombinant1件: D02958 --1件: 288
3ADVATE (rAHF - PFM)1件: Antihemophilic factor, human recombinant1件: D02958 --1件: 288
4ADVATE (rAHF-PFM)1件: Antihemophilic factor, human recombinant1件: D02958 --1件: 288
5ADVATE 1000 IU powder and solvent for solution for injection1件: Antihemophilic factor, human recombinant1件: D02958 --1件: 288
6ADVATE 1000IU powder and solvent for solution for injection1件: Antihemophilic factor, human recombinant1件: D02958 --1件: 288
7ADVATE 500 IU powder and solvent for solution for injection1件: Antihemophilic factor, human recombinant1件: D02958 --1件: 288
8Alphanate1件: Von Willebrand factor human---1件: 288
9Alphanate 1000 I.U.1件: Von Willebrand factor human---1件: 288
10Alphanate 1500 I.U.1件: Von Willebrand factor human---1件: 288
11Alphanate SD/HT1件: Von Willebrand factor human---1件: 288
12ALPHANATE*INF 1F 1000UI+F 10ML1件: Von Willebrand factor human---1件: 288
13ALPHANATE*INF 1F 1500UI+F 10ML1件: Von Willebrand factor human---1件: 288
14ALPHANATE*INF 1F 250UI+F 5ML1件: Von Willebrand factor human---1件: 288
15ALPHANATE*INF 1F 500UI+F 5ML1件: Von Willebrand factor human---1件: 288
16Antihemophilic Factor (Recombinant)----1件: 288
17APCC, aPCC + TXA----1件: 288
18ARC 1779----2件: 64, 288
19ARC1779----2件: 64, 288
20ARC1779 Injection----2件: 64, 288
21BAX 111----1件: 288
22BAX111----1件: 288
23Biostate----1件: 288
24Biostate®----1件: 288
25BIVV001 (rFVIIIFc-VWF-XTEN)----1件: 288
26Blood coagulation Factor VIII and vWF, human1件: Beroctocog alfa---1件: 288
27Blood sample----18件: 8, 13, 46, 49, 51, 53, 61, 65, 66, 84, 96, 97, 107, 127, 235, 274, 288, 299
28BORTEZOMIB1件: Bortezomib1件: D03150 1件: PSMB5 💬8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬16件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331
29Catridecacog1件: Catridecacog1件: D10532 --2件: 97, 288
30Chloride1件: Chloride ion---29件: 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 271, 288, 296, 297, 299, 338
31Cluvot----1件: 288
32Coagadex1件: Coagulation factor X human---1件: 288
33Coagulación factor VIII1件: Beroctocog alfa---1件: 288
34Coagulation factor VIII1件: Beroctocog alfa---1件: 288
35Coagulation factor X1件: Coagulation factor X human---1件: 288
36Coagulation factor XIII1件: Factor XIII (human)---1件: 288
37CoFactor----3件: 6, 265, 288
38Cyclophosphamide1件: Cyclophosphamide2件: D00287 ,
D07760 		--45件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
39DDAVP1件: Desmopressin2件: D00291 ,
D02235 		2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 75, 288
40DDAVP (Desmopressin)1件: Desmopressin2件: D00291 ,
D02235 		2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬1件: 288
41Desmopressin1件: Desmopressin2件: D00291 ,
D02235 		2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬5件: 6, 64, 72, 225, 288
42Desmopressin acetate2件: Acetate,
Desmopressin		2件: D00291 ,
D02235 		2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 64, 288
43Desmopressine1件: Desmopressin2件: D00291 ,
D02235 		2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 225, 288
44Diagnostic Test: blood sample , doppler of uterine vessel and placenta----1件: 288
45Diagnostic Test: fibrinogen plasma concentration, coagulation factor XIII activity2件: Factor XIII (human),
Fibrinogen human		---1件: 288
46Efanesoctocog alfa1件: Efanesoctocog alfa---1件: 288
47Efanesoctocog alfa (BIVV001)1件: Efanesoctocog alfa---1件: 288
48Emicizumab1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
49Emicizumab (ACE910, RO5534262)1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
50Emicizumab Injection1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
51Eqwilate----1件: 288
52F13CD----1件: 288
53F8VR----1件: 288
54FACTANE 200 IU/ml----1件: 288
55Factor VIII1件: Beroctocog alfa---1件: 288
56Factor VIII concentrate1件: Beroctocog alfa---1件: 288
57Factor von Willebrand1件: Von Willebrand factor human---1件: 288
58FACTOR X1件: Coagulation factor X human---1件: 288
59Factor XIII1件: Factor XIII (human)---3件: 51, 97, 288
60Factor XIII Concentrate (Human)1件: Factor XIII (human)---1件: 288
61Factor XIII Concentrate (Human), Pasteurized1件: Factor XIII (human)---1件: 288
62Fanhdi----1件: 288
63FANHDI 100 UI----1件: 288
64Fanhdi 100 UI FVIII-120 UI FVW----1件: 288
65FANHDI 25 UI----1件: 288
66Fanhdi 25 UI FVIII-30 UI FVW----1件: 288
67FANHDI 250UI*1F 250UI+F 10ML----1件: 288
68FANHDI 50 UI----1件: 288
69Fanhdi 50 UI FVIII-60 UI FVW----1件: 288
70FANHDI*INF FL 250UI+SIR SOLV+S----1件: 288
71FANHDI*INF FL 500UI+SIR SOLV+S----1件: 288
72FANHDI*INF FL1000UI+SIR SOLV+S----1件: 288
73FANHDI*INF FL250UI+SIR SOLV+S----1件: 288
74Fibrinogen1件: Fibrinogen human---3件: 14, 65, 288
75Fibrogammin P----1件: 288
76Fibrogammin® P----1件: 288
77Fibrogammin®P----1件: 288
78FXIII Concentrate (Human)----1件: 288
79FXIII Concentrate (Human) (FXIII)----1件: 288
80Haemate P----1件: 288
81Haemate P® (Human Coagulation Factor VIII)2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288
82Haemate-P, Wilate1件: Von Willebrand factor human---1件: 288
83Haemate® P 250----1件: 288
84Hemlibra1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
85Hemlibra®1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
86HEMOFIX----1件: 288
87HUMAN COAGULATION FACTOR VIII2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288
88Human coagulation Factor VIII / von Willebrand Factor3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288
89Human coagulation factor VIII associated with Von Willebrand factor (VWF)2件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288
90HUMAN COAGULATION FACTOR VIII, VON WILLEBRAND FACTOR COMPLEX3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288
91Human Coagulation FACTOR X1件: Coagulation factor X human---1件: 288
92Human factor X1件: Coagulation factor X human---1件: 288
93HUMAN VON WILLEBRAND FACTOR1件: Von Willebrand factor human---1件: 288
94Human von Willebrand factor (VWF) and coagulation factor VIII (FVIII)2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288
95Human VWF/FVIII concentrate----1件: 288
96Humate-P1件: Von Willebrand factor human---1件: 288
97IL-111件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
98Interleukin 111件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
99Interleukin-111件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬2件: 96, 288
100Marketed plasma-derived VWF/FVIII concentrate----1件: 288
101Minirin1件: Desmopressin2件: D00291 ,
D02235 		2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 64, 288
102Minrin----1件: 288
103Natriumchlorid1件: Sodium chloride1件: D02056 --1件: 288
104Natriumchlorid 0,9 %1件: Sodium chloride1件: D02056 --1件: 288
105Neumega (Oprelvekin, Interleukin 11, IL-11)1件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
106NN 1841----1件: 288
107NN1841----1件: 288
108OBI-1----1件: 288
109OBIZUR1件: Susoctocog alfa1件: D10831 --1件: 288
110Obyoctocog alfa----1件: 288
111Octanate1件: Beroctocog alfa---1件: 288
112OCTANATE 100 UI/ml, poudre et solvant pour solution injectable1件: Beroctocog alfa---1件: 288
113OCTANATE 50 UI/ml, poudre et solvant pour solution injectable1件: Beroctocog alfa---1件: 288
114OCTOCOG ALFA1件: Antihemophilic factor, human recombinant1件: D02958 --1件: 288
115Octostim----2件: 64, 288
116Oprelvekin1件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
117Oprelvekin, Interleukin 11, IL-111件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
118Optivate----1件: 288
119Optivate® (Human Coagulation Factor VIII)1件: Antihemophilic factor human---1件: 288
120Other: Use of a postpartum diary and additional blood draws----1件: 288
121Other: Use of a postpartum diary and additional blood draws.----1件: 288
122Physiologische Kochsalzlösung Fresenius - Infusionslösung----1件: 288
123Phytomenadione1件: Phylloquinone1件: D00148 --1件: 288
124Plasma-derived FVIII/VWF concentrate----1件: 288
125Prednisone1件: Prednisone1件: D00473 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
126Prothrombin1件: Prothrombin---1件: 288
127Prothrombin Complex Concentrate2件: Factor IX Complex (Human),
Prothrombin		---1件: 288
128RAHF1件: Antihemophilic factor, human recombinant1件: D02958 --1件: 288
129Recombinant coagulation FVIII Fc – von Willebrand factor – XTEN fusion protein1件: Von Willebrand factor human---1件: 288
130Recombinant coagulation FVIII Fc –von Willebrand factor – XTEN fusion protein1件: Von Willebrand factor human---1件: 288
131Recombinant factor VIIII (rFVIII)----1件: 288
132Recombinant Factor XIII1件: Factor XIII (human)---1件: 288
133Recombinant Factor XIII (rFXIII)1件: Factor XIII (human)---2件: 97, 288
134RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTO2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288
135RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR -2件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288
136RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR - XTEN FUSION PROTEIN3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288
137RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR -XTEN FUSION PROTEIN2件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288
138Recombinant human von Willebrand Factor2件: Von Willebrand factor human,
Vonicog alfa		1件: D08681 --1件: 288
139Recombinant interleukin-111件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
140Recombinant porcine coagulation factor VIII (B domain deleted)1件: Beroctocog alfa---1件: 288
141Recombinant porcine coagulation factor VIII (B-domain deleted)1件: Beroctocog alfa---1件: 288
142Recombinant Von Willebrand factor1件: Von Willebrand factor human---1件: 288
143Recombinant von Willebrand Factor (rVWF)1件: Von Willebrand factor human---1件: 288
144Recombinant von Willebrand Factor 1300IU1件: Vonicog alfa1件: D08681 --1件: 288
145Recombinant von Willebrand Factor 650IU1件: Vonicog alfa1件: D08681 --1件: 288
146Recombinant von Willebrand factor : recombinant FVIII (rVWF:rFVIII)1件: Von Willebrand factor human---1件: 288
147Recomibnant human Von Willebrand Factor2件: Von Willebrand factor human,
Vonicog alfa		1件: D08681 --1件: 288
148RFVIIa1件: Coagulation factor VIIa Recombinant Human1件: D00172 --1件: 288
149RFVIIa, rFVIIa + TXA1件: Coagulation factor VIIa Recombinant Human1件: D00172 --1件: 288
150RFVIII----1件: 288
151Rituxan1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬4件: 46, 60, 256, 288
152Rituximab1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬49件: 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
153RO5534262 EMICIZUMAB1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
154Rurioctocog alfa pegol1件: Rurioctocog alfa pegol1件: D10760 --1件: 288
155RVWF----1件: 288
156Saline solution----4件: 2, 34, 288, 299
157Simvastatin1件: Simvastatin1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
158Simvastatine1件: Simvastatin1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 6, 13, 288
159Sodium chloride2件: Chloride ion,
Sodium chloride		1件: D02056 --21件: 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 168, 193, 227, 228, 271, 288, 299
160SODIUM CHLORIDE SOLUTION 0.9%2件: Chloride ion,
Sodium chloride		1件: D02056 --3件: 60, 288, 299
161Standard of Care for Haemophilia A----1件: 288
162Standard of Care FVIII Replacement therapy----1件: 288
163Steroid----1件: 288
164Sublingual videomicroscopy----1件: 288
165TAK-672----1件: 288
166Tranexamic acid1件: Tranexamic acid1件: D01136 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬6件: 46, 70, 215, 227, 288, 299
167Tranexamic Acid Injection [Cyklokapron]1件: Tranexamic acid1件: D01136 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬1件: 288
168Uterine----3件: 118, 280, 288
169Vessel----4件: 13, 51, 271, 288
170VEYONDI 650IU powder and solvent for solution for injection----1件: 288
171Veyvondi1件: Vonicog alfa1件: D08681 --1件: 288
172VEYVONDI 1300I IU powder and solvent for solution for injection1件: Vonicog alfa1件: D08681 --1件: 288
173VEYVONDI 1300IU powder and solvent for solution for injection1件: Vonicog alfa1件: D08681 --1件: 288
174VEYVONDI 650IU powder and solvent for solution for injection1件: Vonicog alfa1件: D08681 --1件: 288
175Von willebrand factor1件: Von Willebrand factor human---2件: 64, 288
176Von Willebrand factor (Recombinant)1件: Von Willebrand factor human---1件: 288
177Von Willebrand factor and coagulation factor VIII in combination2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288
178Von Willebrand Factor Antigen1件: Von Willebrand factor human---1件: 288
179Von Willebrand Factor Ristocetin Cofactor1件: Von Willebrand factor human---1件: 288
180Von Willebrand Faktor----1件: 288
181Voncento1件: Von Willebrand factor human---1件: 288
182Voncento, Biostate®1件: Von Willebrand factor human---1件: 288
183Voncento®1件: Von Willebrand factor human---1件: 288
184VONICOG ALFA1件: Vonicog alfa1件: D08681 --1件: 288
185VWD factor VIII concentrate1件: Beroctocog alfa---1件: 288
186VWF replacement therapy with Wilate1件: Von Willebrand factor human---1件: 288
187VWF SD-35-DH----1件: 288
188VWF-containing products----1件: 288
189VWF/FVIII products----1件: 288
190WILATE1件: Von Willebrand factor human---1件: 288
191Wilate 10001件: Von Willebrand factor human---1件: 288
192WILATE 1000 I.U.1件: Von Willebrand factor human---1件: 288
193WILATE 4501件: Von Willebrand factor human---1件: 288
194Wilate 5001件: Von Willebrand factor human---1件: 288
195WILATE 500 I.U.1件: Von Willebrand factor human---1件: 288
196WILATE 9001件: Von Willebrand factor human---1件: 288
197WILATE® 4501件: Von Willebrand factor human---1件: 288
198WILFACTIN----1件: 288
199Willfact----1件: 288
200Wiloctin----1件: 288