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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1(R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE1件: Pyrazole---1件: 58
2(R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1METHYL-1H-PYRAZOLE-4-CARBOXAMIDE1件: Pyrazole---1件: 58
3(R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1METHYL-1HPYRAZOLE-4-CARBOXAMIDE----1件: 58
41-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride1件: Piperazine6件: D00807 ,
D01393 ,
D02127 ,
D02145 ,
D05486 ,
D06224 		--1件: 58
53D electrocardiographic mapping (ECM)----1件: 58
6Acetylcysteine1件: Acetylcysteine1件: D00221 --20件: 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
7Adenosine1件: Adenosine1件: D00045 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65
8Air----8件: 3, 13, 51, 58, 85, 97, 193, 299
9Alcohol1件: Ethanol4件: D00068 ,
D02798 ,
D04855 ,
D06542 		--4件: 13, 58, 279, 298
10Alcohol Septal Ablation1件: Ethanol4件: D00068 ,
D02798 ,
D04855 ,
D06542 		--1件: 58
11Amyl Nitrite2件: Amyl Nitrite,
Nitrite		1件: D00517 3件: GUCY1A1,
GUCY1A2,
GUCY1B1 💬		11件: Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
12Amyl nitrite inhalation2件: Amyl Nitrite,
Nitrite		1件: D00517 3件: GUCY1A1,
GUCY1A2,
GUCY1B1 💬		11件: Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
13Antiarrhythmic drugs----1件: 58
14Arginina1件: Arginine1件: D02982 --2件: 58, 78
15Arginine1件: Arginine1件: D02982 --11件: 46, 58, 67, 78, 96, 97, 98, 113, 210, 251, 299
16Aspirin1件: Acetylsalicylic acid1件: D00109 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬12件: 13, 22, 34, 46, 49, 51, 58, 86, 113, 158, 210, 231
17Atorvastatin1件: Atorvastatin3件: D00258 ,
D00887 ,
D07474 		1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
18B-lines SE----3件: 58, 86, 215
19Behavioral: Lifestyle----1件: 58
20Bluefish1件: Bluefish---1件: 58
21BNP----2件: 46, 58
22BNP blood sample test----1件: 58
23C01EB18----1件: 58
24Candesartan1件: Candesartan1件: D00522 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 58, 67
25Carnitine1件: Levocarnitine3件: D02030 ,
D02176 ,
D04713 		--9件: 5, 13, 58, 86, 96, 97, 265, 298, 316
26CAS Name: 1,4-Benzoxazepin-5(2H)-one, 3,4-dihydro-4-(2-pyrimidinylmethyl)-7-[4- (trifluoromethoxy)phenyl] IUPAC Name: 4-(Pyrimidin-2-ylmethyl)-7-[4- (trifluoromethoxy)phenyl]-3,4-dihydro-1,4-benzoxazepin-5(2H)-one----1件: 58
27CAS Name: 1,4-Benzoxazepin-5(2H)-one, 3,4-dihydro-4-(2-pyrimidinylmethyl)-7-[4-(trifluoromethoxy)phenyl] IUPAC Name: 4-(Pyrimidin-2-ylmethyl)-7-[4-(trifluoromethoxy)phenyl]-3,4-dihydro-1,4-benzoxazepin-5(2H)-one----1件: 58
28Cibenzoline1件: Cibenzoline1件: D03492 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 58
29CK-3773274----1件: 58
30CK-3773274 (10 - 30 mg)----1件: 58
31CK-3773274 (5 - 15 mg)----1件: 58
32CK-3773274 (5 - 20 mg)----1件: 58
33CK-3773274 (5 mg, 10 mg, 15 mg and 20 mg)----1件: 58
34CK-3773274 - Granules in Capsule----1件: 58
35CK-3773274 - Tablets----1件: 58
36Coronary flow reserve SE----3件: 58, 86, 215
37CT-G20----1件: 58
38Cufence1件: Triethylenetetramine---2件: 58, 171
39Cyclosporine1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
40Cyclosporine A1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬11件: 19, 20, 36, 49, 50, 53, 58, 60, 107, 234, 283
41Diagnostic Test: Air venous plethysmography----1件: 58
42Diagnostic Test: Echocardiography----1件: 58
43Diagnostic Test: Electrocardiogram----1件: 58
44Diagnostic Test: Exercise Stress Transthoracic Echocardiogram----1件: 58
45Diagnostic Test: Holter ECG----1件: 58
46Diagnostic Test: Phosphorous Magnetic Resonance Spectroscopy1件: Phosphorus---1件: 58
47Diagnostic Test: Upper member arterial Doppler echography with analysis of FMD----1件: 58
48Diastolic function SE----3件: 58, 86, 215
49Diltiazem1件: Diltiazem3件: D00616 ,
D03830 ,
D07845 		4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 51, 58, 86
50Diovan1件: Valsartan1件: D00400 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
51Diovan 160 mg1件: Valsartan1件: D00400 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
52Diovan 40 mg1件: Valsartan1件: D00400 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
53Diovan 80 mg1件: Valsartan1件: D00400 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
54Dobutamine1件: Dobutamine4件: D00632 ,
D03879 ,
D03880 ,
D03881 		1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 57, 58, 215
55Echo and myocardial contrast echocardiography perfusion imaging----1件: 58
56Echocardiography (TEE)----1件: 58
57Eleclazine1件: Eleclazine1件: D11155 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 58
58Endothelial function biomarkers----1件: 58
59Entresto1件: Valsartan1件: D00400 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
60Esmolol1件: Esmolol2件: D00644 ,
D07916 		1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 58
61Gadolinium1件: Gadolinium---6件: 13, 34, 46, 58, 65, 86
62Gold1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318
63Gradient----4件: 58, 86, 149, 215
64GS-6615 3 mg----1件: 58
65GS-6615 3 mg Pink----1件: 58
66GS-6615 3 mg White----1件: 58
67GS-6615 6 mg----1件: 58
68GS-6615 6 mg White----1件: 58
69Gutron 2,5mg----1件: 58
70Gutron 5mg----1件: 58
71Hyperpolarized 13C-Pyruvate----1件: 58
72IMB-1018972----1件: 58
73Imukin----3件: 18, 58, 228
74IMUKIN - 6 FLACONI 0.5 ML 100 MCG----2件: 18, 58
75Insertable cardiac monitor1件: Methamidophos---1件: 58
76LCZ696----1件: 58
77LCZ696 100 mg----1件: 58
78LCZ696 200 mg----1件: 58
79LCZ696 50 mg----1件: 58
80Left ventricular contractile reserve SE----3件: 58, 86, 215
81Left ventricular outflow tract gradient SE----3件: 58, 86, 215
82Losartan1件: Losartan2件: D00357 ,
D08146 		1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
83Losartan Bluefish 50 mg2件: Bluefish,
Losartan		2件: D00357 ,
D08146 		1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
84Magnetic resonance imaging (MRI) with gadolinium enhancement1件: Gadolinium---1件: 58
85Magnetic resonance imaging (MRI) without gadolinium enhancement1件: Gadolinium---1件: 58
86Mangafodipir1件: Mangafodipir1件: D08262 --2件: 13, 58
87MAVACAMTEN1件: Mavacamten1件: D12265 1件: MYH7 💬7件: Adrenergic signaling in cardiomyocytes, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Thyroid hormone signaling pathway, Viral myocarditis, cGMP-PKG signaling pathway 💬1件: 58
88MEK162----2件: 58, 195
89Metoprolol1件: Metoprolol3件: D00601 ,
D02358 ,
D05011 		1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226
90Metoprolol succinate1件: Metoprolol3件: D00601 ,
D02358 ,
D05011 		1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 57, 58, 113, 193
91Metoprololsuccinat----1件: 58
92Midodrine1件: Midodrine2件: D01307 ,
D08220 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬3件: 6, 17, 58
93MIDODRINE HYDROCHLORIDE1件: Midodrine2件: D01307 ,
D08220 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
94Mitral regurgitation SE----3件: 58, 86, 215
95MONITOR1件: Methamidophos---20件: 2, 11, 13, 19, 28, 46, 49, 58, 65, 70, 81, 85, 86, 98, 113, 118, 129, 298, 299, 300
96MYK-461----1件: 58
97N-Acetylcysteine1件: Acetylcysteine1件: D00221 --11件: 6, 13, 19, 20, 49, 58, 85, 111, 164, 299, 337
98Nitrate1件: Nitrate1件: D02313 --3件: 58, 113, 299
99Nitrite1件: Nitrite---3件: 58, 86, 299
100NO----12件: 6, 13, 46, 58, 62, 86, 96, 97, 222, 226, 299, 321
101Other: Exercise echocardiography----1件: 58
102Other: Mangafodipir trisodium1件: Mangafodipir1件: D08262 --1件: 58
103Other: Squat-to-stand maneuver----1件: 58
104Other: Valsalva----1件: 58
105Other: Walk distance test----1件: 58
106Perhexiline1件: Perhexiline2件: D05442 ,
D08340 		8件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CPT1A,
CPT1B,
CPT1C,
CPT2 💬		47件: AMPK signaling pathway, Adipocytokine signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Dopaminergic synapse, Fatty acid degradation, Fatty acid metabolism, GABAergic synapse, Glucagon signaling pathway, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin resistance, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, PPAR signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Thermogenesis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 58, 272
107Perindopril1件: Perindopril2件: D00624 ,
D03753 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬4件: 58, 113, 167, 222
108PERINDOPRIL ARGININA2件: Arginine,
Perindopril		3件: D00624 ,
D02982 ,
D03753 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 58
109Perindopril arginine2件: Arginine,
Perindopril		3件: D00624 ,
D02982 ,
D03753 		1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 58
110Perxexiline----1件: 58
111Pexsig----1件: 58
112Phosphorous1件: Phosphorus---1件: 58
113Piperazine1件: Piperazine6件: D00807 ,
D01393 ,
D02127 ,
D02145 ,
D05486 ,
D06224 		--2件: 58, 272
114Pirfenidone1件: Pirfenidone1件: D01583 6件: CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬		84件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
115Post-CPB Drug: Dobutamine Hydrochloride1件: Dobutamine4件: D00632 ,
D03879 ,
D03880 ,
D03881 		1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 58
116Pre and post-CPB Drug: Dobutamine Hydrochloride1件: Dobutamine4件: D00632 ,
D03879 ,
D03880 ,
D03881 		1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 58
117Procaptan----1件: 58
118PROCAPTAN - 10 MG COMPRESSE RIVESTITE CON FILM 60 COMPRESSE IN CONTENITORE PER COMPRESSE PP----1件: 58
119PROCAPTAN - 5 MG COMPRESSE RIVESTITE CON FILM 10 COMPRESSE IN CONTENITORE PER COMPRESSE PP----1件: 58
120Pulmonary hemodynamics SE----3件: 58, 86, 215
121Pyrazole1件: Pyrazole---1件: 58
122RANEXA1件: Ranolazine2件: D05700 ,
D05701 		--1件: 58
123RANEXA - 750 MG - COMPRESSA A RILASCIO PROLUNGATO- USO ORALE - BLISTER (PVC/PVDC/ALLUMINIO) 60 COMPRESSE1件: Ranolazine2件: D05700 ,
D05701 		--1件: 58
124RANEXA*60CPR 500MG R.P.1件: Ranolazine2件: D05700 ,
D05701 		--1件: 58
125RANEXA*60CPR 750MG R.P.1件: Ranolazine2件: D05700 ,
D05701 		--1件: 58
126Ranolazina1件: Ranolazine2件: D05700 ,
D05701 		--1件: 58
127Ranolazina Ranexa1件: Ranolazine2件: D05700 ,
D05701 		--1件: 58
128Ranolazine1件: Ranolazine2件: D05700 ,
D05701 		--6件: 2, 58, 86, 96, 113, 114
129Ranolazine 1000 mg PR tablets1件: Ranolazine2件: D05700 ,
D05701 		--1件: 58
130Ranolazine 500 mg PR tablets1件: Ranolazine2件: D05700 ,
D05701 		--1件: 58
131Ranolazine 750 mg PR tablets1件: Ranolazine2件: D05700 ,
D05701 		--1件: 58
132Ranolazine PR (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die1件: Ranolazine2件: D05700 ,
D05701 		--1件: 58
133RAS----4件: 6, 13, 58, 66
134Regadenoson1件: Regadenoson1件: D05711 1件: ADORA2A 💬7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 58
135RF catheter ablation----1件: 58
136Sacubitril1件: Sacubitril1件: D10225 1件: MME 💬4件: Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬1件: 58
137SACUBITRIL VALSARTAN2件: Sacubitril,
Valsartan		2件: D00400 ,
D10225 		2件: AGTR1,
MME 💬		19件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hematopoietic cell lineage, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Protein digestion and absorption, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
138Sacubitril/Valsartan2件: Sacubitril,
Valsartan		2件: D00400 ,
D10225 		2件: AGTR1,
MME 💬		19件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hematopoietic cell lineage, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Protein digestion and absorption, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 58
139Sodium Nitrate2件: Nitrate,
Sodium nitrate		1件: D02313 --2件: 58, 113
140Spironolactone1件: Spironolactone1件: D00443 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬7件: 58, 67, 86, 113, 210, 218, 225
141Surgical Septal Myectomy----1件: 58
142Trans-right ventricular alcohol septal ablation (TRVASA)1件: Ethanol4件: D00068 ,
D02798 ,
D04855 ,
D06542 		--1件: 58
143Treatment BX1514M----1件: 58
144Trientine1件: Triethylenetetramine---2件: 58, 171
145Trientine Dihydrochloride1件: Triethylenetetramine---2件: 58, 171
146Triethylinetetramine dihydrochloride----1件: 58
147Trimetazidine1件: Trimetazidine1件: D08642 --3件: 2, 58, 86
148Trimetazidine Dihydrochloride1件: Trimetazidine1件: D08642 --2件: 2, 58
149Trimetazidine Dihydrochloride 20mg1件: Trimetazidine1件: D08642 --1件: 58
150TY-0305----1件: 58
151Use of bioanalytical assay to monitor plasma levels of perhexiline2件: Methamidophos,
Perhexiline		2件: D05442 ,
D08340 		8件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
CPT1A,
CPT1B,
CPT1C,
CPT2 💬		47件: AMPK signaling pathway, Adipocytokine signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Dopaminergic synapse, Fatty acid degradation, Fatty acid metabolism, GABAergic synapse, Glucagon signaling pathway, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin resistance, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, PPAR signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Thermogenesis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 58
152Valsartan1件: Valsartan1件: D00400 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 57, 58, 66, 75, 218, 222, 224
153Vastarel----2件: 2, 58
154Vastarel 20mg film coated tablets----1件: 58