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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1AAV BBP-631----1件: 81
2Abiraterone1件: Abiraterone---2件: 75, 81
3Abiraterone Acetate2件: Abiraterone,
Acetate		---2件: 75, 81
4Acetate1件: Acetate---43件: 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
5ATR-101----2件: 75, 81
6Balance1件: Isoxaflutole---8件: 6, 11, 13, 81, 113, 122, 149, 299
7Behavioral: quality of life assessment----1件: 81
8Bone balance measurements1件: Isoxaflutole---1件: 81
9Chronocort----1件: 81
10Chronocort 10mg----1件: 81
11Chronocort 5mg----1件: 81
12Chronocort®----1件: 81
13Chronocort® 10 mg----1件: 81
14Chronocort® 20 mg----1件: 81
15Chronocort® 5 mg----1件: 81
16CI-984, 17AA70, PD 132301-2----1件: 81
17Conventional Glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone)6件: Acetate,
Cortisone acetate,
Dexamethasone,
Hydrocortisone,
Prednisolone,
Prednisone		20件: D00088 ,
D00292 ,
D00472 ,
D00473 ,
D00973 ,
D00975 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D01998 ,
D02156 ,
D02174 ,
D02591 ,
D02592 ,
D03301 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
18Cortef1件: Hydrocortisone cypionate1件: D00976 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 81, 83
19Corticotropin1件: Corticotropin1件: D00146 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬9件: 2, 13, 46, 75, 78, 81, 84, 205, 222
20Cortisol1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 81, 98
21Cortison----1件: 81
22Cortisone1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
23Cortisone acetate3件: Acetate,
Cortisone acetate,
Hydrocortisone		2件: D00088 ,
D00973 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
24Crinecerfont----1件: 81
25Crinecerfont is a novel non-peptide selective corticotropin releasing factor 1 (CRF1 ) receptor antagonist.1件: Corticotropin1件: D00146 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 81
26Dectancyl----1件: 81
27Dexamethasone1件: Dexamethasone9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
28Dexamethasone 0,1 mg Tablets1件: Dexamethasone9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
29Dexamethasone 0.5mg Tablet1件: Dexamethasone9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
30Dexamethasone 1,5 mg Tablets1件: Dexamethasone9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
31Dexamethasone 2mg Tablets1件: Dexamethasone9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
32DIURF-006----1件: 81
33Dual release hydrocortisone (plenadren)1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
34Efmody 10 mg modified release hard capsules1件: Manganese citrate---1件: 81
35Efmody 5 mg modified release hard capsules1件: Manganese citrate---1件: 81
36Fludrocortisone1件: Fludrocortisone2件: D00986 ,
D07967 		1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬3件: 6, 17, 81
37Flutamide1件: Flutamide1件: D00586 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 81
38Hormonal balance measurements1件: Isoxaflutole---1件: 81
39Hydrocortisone1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
40Hydrocortisone (Solucortef)1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
41Hydrocortisone 10mg Tablet1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
42Hydrocortisone 10mg Tablets1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
43Hydrocortisone 20mg Tablets1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
44HYDROCORTISONE MICRONIZED1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
45Hydrocortisone Modified Release Capsules1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
46Hydrocortisone sodium acetate3件: Acetate,
Hydrocortisone,
Sodium acetate		2件: D00088 ,
D01779 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
47HYDROCORTISONE SODIUM PHOSPHATE2件: Hydrocortisone,
Phosphate ion		1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 53, 81, 83
48HYDROCORTISONE SODIUM SUCCINATE1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 81, 83, 97
49Hydrocortisone tablet 2.5 mg1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
50Hydrocortisone withdrawal1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
51HYDROCORTISONE- hydrocortisone tablet1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
52IDROCORTISONE----1件: 81
53Infacort----1件: 81
54Infacort®----1件: 81
55Insulin pump (Medtronic)----1件: 81
56Letrozole1件: Letrozole1件: D00964 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬2件: 81, 89
57Metabolic balance measurements1件: Isoxaflutole---1件: 81
58Metformin1件: Metformin2件: D00944 ,
D04966 		2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
59METFORMIN HYDROCHLORIDE1件: Metformin2件: D00944 ,
D04966 		2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬5件: 81, 158, 265, 299, 301
60Metformine1件: Metformin2件: D00944 ,
D04966 		2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬3件: 46, 81, 299
61Metformine Sandoz 850 mg filmomhulde tabletten1件: Metformin2件: D00944 ,
D04966 		2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬1件: 81
62MONITOR1件: Methamidophos---20件: 2, 11, 13, 19, 28, 46, 49, 58, 65, 70, 81, 85, 86, 98, 113, 118, 129, 298, 299, 300
63National Drug Code: 59762-0074----1件: 81
64NBI-74788----1件: 81
65NBI-77860----1件: 81
66Nevanimibe1件: Nevanimibe1件: D11300 --2件: 75, 81
67Nevanimibe hydrochloride1件: Nevanimibe1件: D11300 --2件: 75, 81
68Nifedipine1件: Nifedipine1件: D00437 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 50, 81
69Phosphate1件: Phosphate ion---33件: 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
70Pioglitazone1件: Pioglitazone2件: D00945 ,
D08378 		1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
71PREDNISOLONE1件: Prednisolone8件: D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬43件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
72Prednisolone 1mg Tablets1件: Prednisolone8件: D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
73Prednisolone 2,5 mg Tablets1件: Prednisolone8件: D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
74Prednisolone 5 mg Tablets1件: Prednisolone8件: D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
75Prednisolone 5mg Tablet1件: Prednisolone8件: D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
76Prednisone1件: Prednisone1件: D00473 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
77Release1件: Manganese citrate---12件: 6, 8, 13, 46, 65, 78, 81, 96, 97, 206, 226, 299
78Sodium acetate2件: Acetate,
Sodium acetate		1件: D01779 --1件: 81
79Solu-Cortef2件: Hydrocortisone cypionate,
Hydrocortisone succinate		2件: D00976 ,
D01442 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 6, 81, 83
80SPR001----1件: 81
81Standard Care----2件: 81, 299
82Standard glucocorticoid therapy----1件: 81
83Subcutaneous hydrocortisone1件: Hydrocortisone1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 81
84TILDACERFONT----1件: 81