Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Administration of Methylprednisolone + Prednisone + Mycophenolate mofetil
(Synonym: Methylprednisolone hemisuccinate)		4件: Methylprednisolone,
Mycophenolate mofetil,
Mycophenolic acid,
Prednisone		11件: D00407 ,
D00473 ,
D00751 ,
D00752 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 ,
D05094 ,
D05095 ,
D05096 		3件: IMPDH1,
IMPDH2,
NR3C1 💬		4件: Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Purine metabolism 💬1件: 49
2Administration of methylprednisolone, paracetamol and dexchlorpheniramine
(Synonym: Methylprednisolone hemisuccinate)		3件: Acetaminophen,
Dexchlorpheniramine,
Methylprednisolone		8件: D00217 ,
D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 ,
D07803 		4件: HRH1,
NR3C1,
PTGS1,
PTGS2 💬		26件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Calcium signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 49
3Administration of rituximab and methylprednisolone
(Synonym: Methylprednisolone hemisuccinate)		2件: Methylprednisolone,
Rituximab		7件: D00407 ,
D00751 ,
D00979 ,
D02994 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		2件: MS4A1,
NR3C1 💬		2件: Hematopoietic cell lineage, Neuroactive ligand-receptor interaction 💬1件: 51
4Corticosteroid treatment (Methylprednisolone or prednisolone)
(Synonym: Methylprednisolone hemisuccinate)		2件: Methylprednisolone,
Prednisolone		14件: D00407 ,
D00472 ,
D00751 ,
D00979 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 64
5Cyclophosphamide, Azathioprine,prednisone,methylprednisolone
(Synonym: Methylprednisolone hemisuccinate)		4件: Azathioprine,
Cyclophosphamide,
Methylprednisolone,
Prednisone		11件: D00238 ,
D00287 ,
D00407 ,
D00473 ,
D00751 ,
D00979 ,
D03033 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 ,
D07760 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 42, 43, 45
6Infliximab, methylprednisolone, methotrexate
(Synonym: Methylprednisolone hemisuccinate)		3件: Infliximab,
Methotrexate,
Methylprednisolone		9件: D00142 ,
D00407 ,
D00751 ,
D00979 ,
D02115 ,
D02598 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		4件: DHFR,
DHFR2,
NR3C1,
TNF 💬		72件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Biosynthesis of cofactors, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Folate biosynthesis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Metabolic pathways, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease, One carbon pool by folate, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 46
7Interferon-beta-1a (Avonex) plus methylprednisolone
(Synonym: Methylprednisolone hemisuccinate)		3件: Human interferon beta,
Interferon beta-1a,
Methylprednisolone		7件: D00407 ,
D00751 ,
D00979 ,
D04554 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		3件: IFNAR1,
IFNAR2,
NR3C1 💬		19件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 13
8Intravenous (i.v.) methylprednisolone 1000 mg, total 9
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 222
9Intravenous Methylprednisolone
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 13, 145
10IV methylprednisolone
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
11IV methylprednisolone (steroids)
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
12Megadose oral methylprednisolone
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
13Methotrexate + Methylprednisolone
(Synonym: Methylprednisolone hemisuccinate)		2件: Methotrexate,
Methylprednisolone		8件: D00142 ,
D00407 ,
D00751 ,
D00979 ,
D02115 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		3件: DHFR,
DHFR2,
NR3C1 💬		6件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Neuroactive ligand-receptor interaction, One carbon pool by folate 💬1件: 46
14Methylprednisolone
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
15Methylprednisolone (drug)
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
16Methylprednisolone (MP)
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 60, 285
17Methylprednisolone (MP) or prednisone (pred)
(Synonym: Methylprednisolone hemisuccinate)		2件: Methylprednisolone,
Prednisone		7件: D00407 ,
D00473 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 66
18Methylprednisolone (or other glucocorticoid)
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 43
19Methylprednisolone (Solu-Medrol)
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 14
20Methylprednisolone 1250 mg/24h x3 days
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
21METHYLPREDNISOLONE ACETATE
(Synonym: Methylprednisolone hemisuccinate)		2件: Acetate,
Methylprednisolone		6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 46, 51
22Methylprednisolone and azathioprine
(Synonym: Methylprednisolone hemisuccinate)		2件: Azathioprine,
Methylprednisolone		8件: D00238 ,
D00407 ,
D00751 ,
D00979 ,
D03033 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 93, 95
23Methylprednisolone and Mycophenolate mofetil
(Synonym: Methylprednisolone hemisuccinate)		3件: Methylprednisolone,
Mycophenolate mofetil,
Mycophenolic acid		10件: D00407 ,
D00751 ,
D00752 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 ,
D05094 ,
D05095 ,
D05096 		3件: IMPDH1,
IMPDH2,
NR3C1 💬		4件: Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Purine metabolism 💬2件: 93, 95
24Methylprednisolone bolus IV 15 mg/kg/d for 3 days.
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 84
25Methylprednisolone hemisuccinate2件: Methylprednisolone,
Methylprednisolone hemisuccinate		6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
26Methylprednisolone IV
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
27METHYLPREDNISOLONE MYLAN Générique
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 66
28Methylprednisolone or budesonide
(Synonym: Methylprednisolone hemisuccinate)		2件: Budesonide,
Methylprednisolone		7件: D00246 ,
D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 96
29Methylprednisolone or Prednisolone
(Synonym: Methylprednisolone hemisuccinate)		2件: Methylprednisolone,
Prednisolone		14件: D00407 ,
D00472 ,
D00751 ,
D00979 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 65
30Methylprednisolone PO
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
31Methylprednisolone pulse
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 66, 220
32METHYLPREDNISOLONE SODIUM HEMISUCCINATE
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 13, 97
33METHYLPREDNISOLONE SODIUM SUCCINATE
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬6件: 13, 46, 49, 50, 51, 211
34Methylprednisolone succinate
(Synonym: Methylprednisolone hemisuccinate)		2件: Methylprednisolone,
Methylprednisolone hemisuccinate		6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
35Methylprednisolone(intravenously in the 1st-2nd-3rd month )
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 66
36Methylprednisolone(intravenously in the 1st-3rd-5th month)
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 66
37Oral 5-ASA+/-topical 5-ASA+IV corticosteroids / PO Methylprednisolone
(Synonym: Methylprednisolone hemisuccinate)		2件: Mesalazine,
Methylprednisolone		7件: D00377 ,
D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 97
38Oral Methylprednisolone 625 mg/24h x3 days
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
39Other: Exposure to methylprednisolone during pregnancy
(Synonym: Methylprednisolone hemisuccinate)		1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 13
40Prednisone (and methylprednisolone)
(Synonym: Methylprednisolone hemisuccinate)		2件: Methylprednisolone,
Prednisone		7件: D00407 ,
D00473 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 43
41Prednisone, methylprednisolone,cyclophosphamides
(Synonym: Methylprednisolone hemisuccinate)		2件: Methylprednisolone,
Prednisone		7件: D00407 ,
D00473 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 42, 43, 45
42Ursodeoxycholic acid+Low Dose Glucocorticoid(Methylprednisolone)
(Synonym: Methylprednisolone hemisuccinate)		2件: Methylprednisolone,
Ursodeoxycholic acid		7件: D00407 ,
D00734 ,
D00751 ,
D00979 ,
D05000 (Name: Methylprednisolone hemisuccinate),
D05001 ,
D05002 		2件: NR1H4,
NR3C1 💬		2件: Bile secretion, Neuroactive ligand-receptor interaction 💬1件: 93