Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Acthar high dose (80 U)1件: Corticotropin1件: D00146 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 49
2Administration of a high dose of desipramine1件: Desipramine2件: D00812 ,
D07791 		2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬1件: 156
3Ambrisentan - high dose1件: Ambrisentan1件: D07077 1件: EDNRA 💬7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86
4AXO-AAV-GM2 High Dose----1件: 19
5BI 655064 high dose----1件: 46
6BIIL 284 BS high dose----1件: 46
7BIIL 284 BS, high dose----1件: 299
8BIIL 284 BS, high dose, adult patients----1件: 299
9BIIL 284 BS, high dose, pediatric patients----1件: 299
10BIRB 796 BS, high dose----1件: 46
11BLI-1300 high dose----1件: 96
12Brazikumab high dose1件: Brazikumab1件: D10912 1件: IL23A 💬9件: C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬1件: 96
13Clobazam High Dose1件: Clobazam1件: D01253 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 144
14CVN424 High Dose----1件: 6
15CVT-301 High Dose----1件: 6
16DNS-7801 (high dose)----1件: 6
17Elamipretide (high dose)1件: Elamipretide1件: D10925 --1件: 21
18EUR-1008 (APT-1008) High Dose----1件: 298
19Fentanyl (High Dose)1件: Fentanyl2件: D00320 ,
D01399 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 215
20High dose----1件: 97
21High dose AFFITOPE® PD03A + Adjuvant----1件: 6
22High dose ANAVEX2-73----1件: 6
23High Dose Aspirin (1300 mg/day)1件: Acetylsalicylic acid1件: D00109 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 13
24High dose BIBF 1120 twice daily----1件: 85
25High Dose Budesonide1件: Budesonide1件: D00246 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 97
26High dose budesonide suspension1件: Budesonide1件: D00246 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 98
27High dose budesonide tablet1件: Budesonide1件: D00246 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 98
28High dose Dexamethasone pulses1件: Dexamethasone9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 63
29High dose lactulose1件: Lactulose1件: D00352 --1件: 291
30High dose levodopa1件: Levodopa1件: D00059 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
31High Dose Mesenchymal Stem Cells (MSCs)----1件: 49
32High Dose MT-1303----1件: 97
33High dose of BIIL 284 BS tablets----1件: 46
34High dose of budesonide1件: Budesonide1件: D00246 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 299
35High dose ORTD-1----1件: 46
36High dose TSO----1件: 96
37High dose vehicle control----1件: 46
38High Dose-VIS649----1件: 66
39High doses of Thiamine y Biotin2件: Biotin,
Thiamine		2件: D00029 ,
D08580 		--1件: 8
40HMPL-004 high dose----1件: 97
41IgPro20 (high dose)----1件: 14
42KPS-0373, High dose----1件: 18
43KW-6356 High Dose----1件: 6
44LiRIS low dose and LiRIS high dose----1件: 226
45LX3305 high dose----1件: 46
46M5049 high dose----1件: 49
47MEDI7183 high dose----1件: 97
48MMX Mesalamine/Mesalazine (High Dose)1件: Mesalazine1件: D00377 --1件: 97
49MT-1303 High dose----1件: 49
50MT-7117 High Dose----1件: 254
51MultiStem high dose1件: MultiStem---1件: 97
52Non-myeloablative high dose immunosuppressive therapy conditioning (HDIT)----1件: 49
53OCU400 High Dose----1件: 90
54PF-06649751 high dose (15 mg QD)1件: Tavapadon1件: D11431 2件: DRD1,
DRD5 💬		10件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬1件: 6
55PXT3003 High Dose----1件: 10
56Ravicti high dose1件: Glycerol phenylbutyrate1件: D10127 --1件: 299
57SA001 High dose----1件: 53
58SEN0014196 (High Dose)----1件: 8
59SHR1459 High Dose----1件: 222
60TAS5315 high dose----1件: 46
61Vitamin D3 - high dose1件: Cholecalciferol1件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬1件: 6
62YRA-1909 high dose----1件: 46