Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1150-mg IVACAFTOR
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
2150mg IVACAFTOR
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
375-mg IVACAFTOR
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
4CF patients with a G551D mutation and treated with Ivacaftor
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
5Deuterated Ivacaftor
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
6Elexacaftor-tezacaftor-ivacaftor exposure
(Synonym: Kalydeco (TN))		3件: Elexacaftor,
Ivacaftor (Synonym: Kalydeco),
Tezacaftor		3件: D09916 (Name: Kalydeco (TN)),
D11041 ,
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
7Elexacaftor/tezacaftor/ivacaftor
(Synonym: Kalydeco (TN))		3件: Elexacaftor,
Ivacaftor (Synonym: Kalydeco),
Tezacaftor		3件: D09916 (Name: Kalydeco (TN)),
D11041 ,
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
8IVACAFTOR
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
9Ivacaftor (proposed INN)
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
10Ivacaftor 125mg tablet
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
11Ivacaftor 150 mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
12Ivacaftor 150 mg or 250 mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
13Ivacaftor 25 mg/75 mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
14IVACAFTOR 59,5mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
15IVACAFTOR 59.5mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
16Ivacaftor 75 mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
17Ivacaftor 75 mg/150 mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
18IVACAFTOR 75mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
19Ivacaftor Exposed
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
20Ivacaftor or elexacaftor/tezacaftor/ivacaftor
(Synonym: Kalydeco (TN))		3件: Elexacaftor,
Ivacaftor (Synonym: Kalydeco),
Tezacaftor		3件: D09916 (Name: Kalydeco (TN)),
D11041 ,
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
21Ivacaftor+lumacaftor
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
22Ivacaftor/Ataluren
(Synonym: Kalydeco (TN))		2件: Ataluren,
Ivacaftor (Synonym: Kalydeco)		2件: D09323 ,
D09916 (Name: Kalydeco (TN))		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
23Ivacaftor/Kalydeco1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
24Ivacaftor/Trikafta
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
25Kalydeco1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
26Kalydeco 150 mg film-c1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
27Kalydeco 150 mg film-coated tablets1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
28Kalydeco 150mg1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
29Lumacaftor / ivacaftor
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
30Lumacaftor plus Ivacaftor
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
31Lumacaftor Plus Ivacaftor Combination
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
32Lumacaftor, Ivacaftor Drug Combination
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
33Lumacaftor-ivacaftor
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
34Lumacaftor-Ivacaftor treatment
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
35Lumacaftor/Ivacaftor
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
36Lumacaftor/ivacaftor 100mg/125mg tablets
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
37Lumacaftor/ivacaftor 200mg/125mg
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
38Lumacaftor/ivacaftor 200mg/125mg tablets
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
39Lumacaftor/ivacaftor 200mg/83mg tablet
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
40Orkambi: contains lumacaftor and ivacaftor
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Lumacaftor		2件: D09916 (Name: Kalydeco (TN)),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
41Tezacaftor/Ivacaftor
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Tezacaftor		2件: D09916 (Name: Kalydeco (TN)),
D11041 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
42Tezacaftor/Ivacaftor + Ivacaftor
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Tezacaftor		2件: D09916 (Name: Kalydeco (TN)),
D11041 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
43Tezacaftor/Ivacaftor 100mg/150mg
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Tezacaftor		2件: D09916 (Name: Kalydeco (TN)),
D11041 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
44Tezacaftor/Ivacaftor/100mg/150mg
(Synonym: Kalydeco (TN))		2件: Ivacaftor (Synonym: Kalydeco),
Tezacaftor		2件: D09916 (Name: Kalydeco (TN)),
D11041 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
45Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor
(Synonym: Kalydeco (TN))		4件: Elexacaftor,
Ivacaftor (Synonym: Kalydeco),
Lumacaftor,
Tezacaftor		4件: D09916 (Name: Kalydeco (TN)),
D10134 ,
D11041 ,
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
46VX-659/Tezacaftor/Ivacaftor
(Synonym: Kalydeco (TN))		3件: Ivacaftor (Synonym: Kalydeco),
Tezacaftor,
VX-659		2件: D09916 (Name: Kalydeco (TN)),
D11041 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
47VX-661 Plus Ivacaftor Combination
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
48VX-661/Ivacaftor
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
49VX-661/ivacaftor (VX-770) 100mg/150 mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
50VX-661/ivacaftor 100 mg/ 150 mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
51VX-661/ivacaftor 100mg/150 mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
52VX-661/ivacaftor 100mg/150mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
53VX-661/ivacaftor 50 mg/ 75 mg
(Synonym: Kalydeco (TN))		1件: Ivacaftor (Synonym: Kalydeco)1件: D09916 (Name: Kalydeco (TN))1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299