Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Amphotericin B
(Synonym: Amphotec 100 mg)		2件: ABELCET; Amphotericin B1件: D00203 --1件: 299
2 Ascorbic acid
(Synonym: Vitamin C 100 Mg Orange Chewable)		4件: Acidum ascorbicum; Ascorbic acid; Iron; Vitamin C1件: D00018 --8件: 10, 97, 192, 206, 210, 211, 212, 298
3 Atenolol
(Synonym: Riva-atenolol 100 mg)		1件: ATENOLOL1件: D00235 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 167
4 Carbamazepine
(Synonym: Tegretol Chewtabs 100 mg)		1件: Carbamazepine1件: D00252 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬2件: 13, 231
5 Carbidopa
(Synonym: Nu-levocarb - Tab 25 Mg/100 mg)		7件: CARBIDOPA; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00558 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬9件: 2, 4, 6, 13, 17, 90, 140, 164, 201
6 Celecoxib
(Synonym: Celecoxib 100 mg)		2件: Celebrex; Celecoxib1件: D00567 1件: PTGS2 💬22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
7 Ciprofloxacin
(Synonym: Ciprofloxacin Tablets USP - 100 mg)		2件: Ciprofloxacin; Ciprofloxacin hydrochloride2件: D00186 ,
D02216 		--5件: 2, 60, 96, 97, 299
8 Fenofibrate
(Synonym: Lipidil Supra 100 mg)		1件: Fenofibrate1件: D00565 1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬5件: 8, 79, 93, 94, 265
9 Flurbiprofen
(Synonym: Ansaid Tablets 100 mg)		1件: FLURBIPROFEN3件: D00330 ,
D01475 ,
D02290 		2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 13, 21, 46
10 Hydrochlorothiazide
(Synonym: Metoprolol Tartrate and Hydrochlorothiazide 100 mg-50 mg)		2件: Esidrix; Hydrochlorothiazide1件: D00340 1件: SLC12A3 💬-4件: 13, 67, 225, 235
11 Leflunomide
(Synonym: Arava 100 mg)		3件: ARAVA; Leflunomide; Leflunomidum1件: D00749 1件: DHODH 💬3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬12件: 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
12 Levodopa
(Synonym: Nu-levocarb - Tab 25 Mg/100 mg)		8件: DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00059 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬8件: 2, 4, 6, 17, 90, 140, 164, 201
13 Losartan
(Synonym: LOSARTAN POTASSIUM 100 mg)		3件: Cozaar; Losartan; LOSARTAN POTASSIUM2件: D00357 (Name: LOSARTAN POTASSIUM TABLETS, 100 MG),
D08146 		1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
14 Meperidine
(Synonym: Demerol 100 mg/ml)		1件: Pethidine2件: D01383 ,
D08343 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 298
15 Metoprolol
(Synonym: Metoprolol Tartrate and Hydrochlorothiazide 100 mg-25 mg)		2件: Metoprolol; METOPROLOL SUCCINATE3件: D00601 ,
D02358 ,
D05011 		1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226
16 Morphine
(Synonym: PMS-morphine Sulfate SR 100 mg)		2件: Morphine; Morphine Sulfate3件: D00842 ,
D02271 ,
D08233 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬6件: 36, 46, 70, 85, 86, 298
17 Niacin
(Synonym: Niacin 100 mg)		2件: Niacin; Nicotinic acid1件: D00049 --4件: 6, 78, 79, 265
18 Nicotinamide
(Synonym: Niacinamide 100 Mg Tablets)		4件: Ginseng; Multivitamin; Niacinamide; Nicotinamide1件: D00036 --11件: 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
19 Pyridoxine
(Synonym: Vitamin B6 100 mg)		2件: PYRIDOXINE; Vitamin B62件: D02179 ,
D08454 		--5件: 6, 93, 145, 206, 320
20 Riboflavin
(Synonym: Vitamin B2 100 mg)		2件: Riboflavin; Vitamin B23件: D00050 ,
D01622 ,
D01913 		--8件: 13, 38, 46, 96, 97, 162, 168, 265
21 Spironolactone
(Synonym: Aldactone 100 mg)		1件: SPIRONOLACTONE1件: D00443 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬7件: 58, 67, 86, 113, 210, 218, 225
22 Theophylline
(Synonym: Theo-dur 100 mg)		1件: Theophylline5件: D00371 ,
D01712 ,
D02017 ,
D06103 ,
D06104 		19件: ADORA1,
ADORA2A,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		24件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 236, 299
23 Thiamine
(Synonym: Vitamin B1 100 mg)		2件: Thiamine; Vitamin B11件: D08580 --5件: 8, 13, 93, 145, 265
24 Tranexamic acid
(Synonym: Cyklokapron 100 mg/ml)		1件: Tranexamic acid1件: D01136 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬6件: 46, 70, 215, 227, 288, 299
25 Ubidecarenone
(Synonym: Now Coq10 100 mg)		3件: Coenzyme Q-10; Coenzyme Q10; CoQ101件: D01065 --13件: 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 193, 214, 215