Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells 1件: Orbcel-C---2件: 94, 95
2 Ascorbic acid
(Synonym: Cda-21 Vitamins With Non-medicinal Probiotic Complex)		4件: Acidum ascorbicum; Ascorbic acid; Iron; Vitamin C1件: D00018 --8件: 10, 97, 192, 206, 210, 211, 212, 298
3 Biotin
(Synonym: Cda-21 Vitamins With Non-medicinal Probiotic Complex)		4件: BIOTIN; Biotina; D-BIOTIN; Vitamin B71件: D00029 --5件: 2, 8, 10, 13, 20
4 CDP323 1件: CDP323---1件: 13
5 Chenodeoxycholic acid
(Synonym: CDCA)		3件: CDCA; Chenodeoxycholic acid; Chenodiol1件: D00163 1件: NR1H4 💬1件: Bile secretion 💬4件: 20, 96, 234, 263
6 Chlorpheniramine
(Synonym: Maxi-Tuss CD)		1件: Clorfenamina4件: D00665 ,
D00668 ,
D07398 ,
D07803 		1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
7 Cisplatin
(Synonym: CDDP)		1件: Cisplatin1件: D00275 --1件: 28
8 Citicoline
(Synonym: CDP-colina)		1件: Citicolina1件: D00057 --1件: 6
9 Cladribine
(Synonym: 2-CdA)		4件: 2-CdA; CLADRIBINA; Cladribine; MAVENCLAD1件: D01370 1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬3件: 11, 13, 94
10 Clindamycin
(Synonym: 7-CDL)		2件: CLINDAMYCIN; Dalacin C phosphate4件: D00277 ,
D01073 ,
D01990 ,
D02132 		--2件: 46, 299
11 Cyanocobalamin
(Synonym: Cda-21 Vitamins With Non-medicinal Probiotic Complex)		2件: Cianocobalamina; Vitamin B124件: D00166 ,
D03615 ,
D03616 ,
D03617 		--5件: 6, 13, 201, 229, 299
12 Dextromethorphan
(Synonym: Safetussin CD)		4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta3件: D00848 ,
D03742 ,
D03744 		6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
13 Diltiazem
(Synonym: Nu-diltiaz-CD Capsules)		2件: Diltiazem; Diltiazem Hydrochloride3件: D00616 (Name: Dilt-CD (TN)),
D03830 ,
D07845 		4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 51, 58, 86
14 Diphenhydramine
(Synonym: Endal CD)		2件: Diphenhydramine; Diphenhydramine hydrochloride6件: D00300 ,
D00669 ,
D02419 ,
D03285 ,
D03360 ,
D03854 		1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬10件: 11, 13, 49, 51, 70, 86, 96, 222, 256, 300
15 Efalizumab
(Synonym: anti-CD11a)		2件: EFALIZUMAB; Raptiva1件: D03959 1件: ITGAL 💬12件: Cell adhesion molecules, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬9件: 11, 13, 37, 46, 49, 53, 61, 95, 96
16 Ethanol
(Synonym: Hand Sanitizer CDS Office Products)		3件: Alcohol; Ethanol; Prednisone4件: D00068 ,
D02798 ,
D04855 ,
D06542 		--7件: 13, 51, 58, 97, 279, 280, 298
17 Folic acid
(Synonym: Cda-21 Vitamins With Non-medicinal Probiotic Complex)		5件: Acide folique; Folate; Folic acid; Multivitamin; Nicotinamide1件: D00070 --6件: 6, 13, 41, 46, 49, 84
18 Inebilizumab
(Synonym: inebilizumab-cdon)		2件: Inebilizumab; Uplizna1件: D11757 (Name: Inebilizumab-cdon)1件: CD19 💬5件: B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬4件: 11, 13, 51, 300
19 Leniolisib
(Synonym: Cdz173 free base)		1件: Leniolisib1件: D11158 3件: PIK3CA,
PIK3CB,
PIK3CD 💬		106件: AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, Metabolic pathways, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Platinum drug resistance, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬2件: 53, 65
20 Methylcellulose
(Synonym: CDMA Fiber Therapy)		1件: Methyl cellulose1件: D04996 --1件: 53
21 Methylphenidate
(Synonym: Metadate CD)		3件: Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin2件: D01296 (Name: METHYLPHENIDATE HYDROCHLORIDE CD),
D04999 		2件: SLC6A2,
SLC6A3 💬		7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬7件: 6, 13, 34, 84, 113, 179, 206
22 Muromonab
(Synonym: Anti-CD3)		3件: Anti-CD3; Muromonab; Muromonab-CD31件: D05092 (Name: Muromonab-CD3)3件: CD3D,
CD3E,
CD3G 💬		11件: Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬3件: 60, 96, 97
23 Niacin
(Synonym: Cda-21 Vitamins With Non-medicinal Probiotic Complex)		2件: Niacin; Nicotinic acid1件: D00049 --4件: 6, 78, 79, 265
24 Obeticholic acid
(Synonym: 6-Ethyl-CDCA)		4件: 6-ECDCA; 6-ethylchenodeoxycholic acid; OBETICHOLIC ACID; Ocaliva1件: D09360 1件: NR1H4 💬1件: Bile secretion 💬3件: 93, 265, 296
25 Ofatumumab
(Synonym: HuMax-CD20)		4件: Arzerra; HuMax-CD20; Kesimpta; Ofatumumab1件: D09314 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬3件: 13, 35, 46
26 Phenylephrine
(Synonym: Safetussin CD)		1件: Phenylephrine2件: D00511 ,
D08365 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
27 Pseudoephedrine
(Synonym: Dicel CD)		1件: Pseudoephedrine4件: D00485 ,
D05648 ,
D05649 ,
D08449 		9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17
28 Pyridoxine
(Synonym: Cda-21 Vitamins With Non-medicinal Probiotic Complex)		2件: PYRIDOXINE; Vitamin B62件: D02179 ,
D08454 		--5件: 6, 93, 145, 206, 320
29 Riboflavin
(Synonym: Cda-21 Vitamins With Non-medicinal Probiotic Complex)		2件: RIBOFLAVIN; Vitamin B23件: D00050 ,
D01622 ,
D01913 		--8件: 13, 38, 46, 96, 97, 162, 168, 265
30 Thiamine
(Synonym: Cda-21 Vitamins With Non-medicinal Probiotic Complex)		2件: THIAMINE; Vitamin B11件: D08580 --5件: 8, 13, 93, 145, 265
31 Toralizumab
(Synonym: Anti-CD40L)		1件: Anti-CD40L1件: D06193 1件: CD40LG 💬14件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬1件: 63