Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Azithromycin
(Synonym: Azithromycin Monohydrate)		5件: AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; Zithromax3件: D02134 ,
D06390 (Name: AZITHROMYCIN MONOHYDRATE),
D07486 		--6件: 13, 84, 85, 96, 228, 299
2 Caffeine 1件: Caffeine2件: D00528 ,
D01453 (Name: Caffeine monohydrate)		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
3 Calcifediol 2件: 25-Hydroxyvitamin D3; CALCIFEDIOL1件: D00122 (Name: Calcifediol monohydrate)1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬2件: 113, 299
4 Cefadroxil 0件: 2件: D00257 ,
D02353 (Name: Cefadroxil monohydrate)		--2件: 222, 240
5 Cephalexin 2件: CEFALEXIN; Cephalexin2件: D00263 ,
D00906 (Name: Cephalexin monohydrate)		--1件: 299
6 Cisapride 1件: CISAPRIDE2件: D00274 ,
D02092 (Name: Cisapride monohydrate)		3件: HTR2A,
HTR3A,
HTR4 💬		7件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬1件: 13
7 Citric acid 1件: Citric acid2件: D00037 ,
D01222 (Name: Citric acid monohydrate)		--2件: 53, 291
8 Cytarabine 1件: Cytarabine3件: D00168 ,
D03046 (Name: Fosteabine sodium monohydrate),
D03637 		--7件: 11, 13, 14, 25, 49, 60, 65
9 D-glucose
(Synonym: Dextrose Monohydrate)		2件: D-glucose; Glucose1件: D00009 --3件: 49, 86, 88
10 Doxycycline
(Synonym: Vibramycin Monohydrate)		4件: Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets5件: D00307 (Name: DOXYCYCLINE MONOHYDRATE),
D02129 ,
D03903 ,
D03904 ,
D07876 		--16件: 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
11 Isoniazid 1件: Isoniazid3件: D00346 ,
D01501 ,
D02002 (Name: Isoniazid sodium methanesulfonate monohydrate)		--2件: 65, 254
12 Lactose 1件: Lactose2件: D00046 ,
D03226 (Name: Lactose monohydrate (NF))		--6件: 2, 6, 13, 97, 228, 310
13 Lapatinib 1件: Lapatinib2件: D04024 (Name: Lapatinib ditosylate monohydrate),
D08108 		2件: EGFR,
ERBB2 💬		50件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction 💬3件: 34, 74, 75
14 Lidocaine
(Synonym: Lidocaine Hydrochloride Monohydrate)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine3件: D00358 ,
D02086 ,
D08127 (Name: Lidocaine hydrochloride monohydrate)		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
15 Metoclopramide 1件: METOCLOPRAMIDE3件: D00726 ,
D02213 (Name: Metoclopramide dihydrochloride monohydrate),
D05008 (Name: Metoclopramide monohydrochloride monohydrate)		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 51
16 Mometasone 1件: Mometasone3件: D00690 ,
D03325 (Name: Mometasone furoate monohydrate),
D08227 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 162
17 Mometasone furoate
(Synonym: Mometasone Furoate Monohydrate)		3件: Mometasone; Mometasone furoate; Nasonex1件: D00690 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 162
18 Nitrofurantoin
(Synonym: Nitrofurantoin monohydrate macrocrystals)		1件: Nitrofurantoin1件: D00439 (Name: NITROFURANTOIN MONOHYDRATE MACROCRYSTALLINE)--1件: 13
19 Olanzapine 2件: OLANZAPINE; Zyprexa2件: D00454 ,
D06623 (Name: Olanzapine pamoate monohydrate)		11件: ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 8
20 Pramipexole 7件: Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL2件: D00559 (Name: Pramipexole dihydrochloride monohydrate),
D05575 		3件: DRD2,
DRD3,
DRD4 💬		8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 2, 6, 20
21 Prednisone 3件: PREDNISONA; PREDNISONE; RAYOS1件: D00473 (Name: Prednisone monohydrate)1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
22 Pyridoxal phosphate 0件: 1件: D00006 (Name: Pyridoxal phosphate monohydrate)--1件: 13
23 Theophylline 1件: Theophylline5件: D00371 ,
D01712 ,
D02017 ,
D06103 (Name: Theophylline monohydrate),
D06104 		19件: ADORA1,
ADORA2A,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		24件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 236, 299