Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Bevantolol
(Synonym: 1--3-m-tolyloxy-propan-2-ol)		1件: Bevantolol---1件: 8
2 Clotrimazole
(Synonym: Terbinafine HCl Chlortimazole and Tolnaftate)		1件: Clotrimazole1件: D00282 --1件: 97
3 Dextrose, unspecified form
(Synonym: 100gm Glucose Tolerance Drink)		2件: Dextrose; Glucose---19件: 2, 6, 13, 49, 50, 56, 60, 65, 70, 75, 86, 88, 96, 160, 195, 226, 254, 257, 299
4 Digoxin
(Synonym: Toloxin)		1件: Digoxin1件: D00298 4件: ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		18件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 8, 46, 210
5 Hydrochlorothiazide
(Synonym: Tolucombi)		2件: Esidrix; Hydrochlorothiazide1件: D00340 1件: SLC12A3 💬-4件: 13, 67, 225, 235
6 Hydrocortisone
(Synonym: NU-DERM Tolereen Anti-pruritic)		6件: Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
7 Imatinib
(Synonym: α--p-toluidide)		4件: Gleevec; GLIVEC; Imatinib; Imatinib Mesylate2件: D01441 ,
D08066 		3件: ABL1,
KIT,
PDGFRA 💬		32件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
8 Itraconazole
(Synonym: Tolsura)		2件: Itraconazole; Sporanox1件: D00350 (Name: TOLSURA)--5件: 3, 65, 96, 227, 299
9 Lactose
(Synonym: Lac-tol Pwr 50gm/pck)		1件: Lactose2件: D00046 ,
D03226 		--6件: 2, 6, 13, 97, 228, 310
10 Procarbazine
(Synonym: N-Isopropyl-α--p-toluamide)		1件: Procarbazine2件: D00478 ,
D08423 		--1件: 65
11 Telmisartan
(Synonym: Tolucombi)		1件: Telmisartan1件: D00627 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 66, 67
12 Terbinafine
(Synonym: Terbinafine HCl Chlortimazole and Tolnaftate)		1件: Terbinafine2件: D02219 ,
D02375 		--3件: 96, 97, 271
13 Tolcapone 3件: Tasmar; Tolcapon; Tolcapone1件: D00786 (Name: Tolcapone)1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬3件: 6, 28, 127
14 Tolfenamic acid 1件: Tolfenamic Acid1件: D01183 (Name: Tolfenamic acid)2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5
15 Tolperisone 1件: Tolperisone1件: D08617 (Name: Tolperisone)--1件: 13
16 Tolterodine 1件: Tolterodine2件: D00646 (Name: Tolterodine),
D01148 (Name: Tolterodine tartrate)		1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 17, 53
17 Tolvaptan 3件: Jinarc; Samsca; Tolvaptan1件: D01213 (Name: Tolvaptan)1件: AVPR2 💬3件: Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬3件: 67, 72, 225
18 Xylose
(Synonym: Xylo-tol Pwr 25gm/pck)		1件: Xylose1件: D06346 --1件: 98