Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Synonym: Trendar Pms Tablets)		5件: Acetaminophen; Oxycodone/Acetaminophen; PARACETAMOL; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬18件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Acetic acid
(Synonym: Treagan Otic)		1件: Acetic acid1件: D00010 --1件: 97
3 Adenosine
(Synonym: MISSHA Time Revolution The First Treatment Essence Intensive)		2件: Adenosine; Ginseng1件: D00045 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65
4 Alitretinoin
(Synonym: 9-cis-Tretinoin)		2件: ALITRETINOIN; Toctino1件: D02815 5件: RARA,
RARB,
RXRA,
RXRB,
RXRG 💬		19件: Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬1件: 49
5 Allantoin
(Synonym: Zzip Cold Sore Treatment)		1件: ALLANTOIN1件: D00121 --1件: 36
6 Antihemophilic factor human
(Synonym: Profilate Heat Treated-wet Method Inj)		6件: Alphanate; Factor VIII; HUMAN COAGULATION FACTOR VIII; Humate-P; Voncento; WILATE---1件: 288
7 Bendamustine
(Synonym: Treanda)		2件: Bendamustine; BENDAMUSTINE HYDROCHLORIDE1件: D07501 (Name: Treanda (TN))--2件: 28, 61
8 Biotin
(Synonym: Bonogen Activator hair loss treatment)		4件: BIOTIN; Biotina; D-BIOTIN; Vitamin B71件: D00029 --5件: 2, 8, 10, 13, 20
9 Butylene glycol
(Synonym: Buddate Reges Intensive Treatment)		0件: 1件: D10695 --2件: 28, 46
10 Caffeine
(Synonym: Trezix)		1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
11 Calcium
(Synonym: Restoration Treatment)		2件: Calcio; Calcium---30件: 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
12 Catridecacog
(Synonym: Tretten)		1件: Catridecacog1件: D10532 --2件: 97, 288
13 Chlorpheniramine
(Synonym: Anakit Insect Sting Treatment Kit)		1件: Clorfenamina4件: D00665 ,
D00668 ,
D07398 ,
D07803 		1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
14 Clindamycin
(Synonym: Clindamycin Phosphate and Tretinoin)		2件: CLINDAMYCIN; Dalacin C phosphate4件: D00277 ,
D01073 ,
D01990 ,
D02132 		--2件: 46, 299
15 Clotrimazole
(Synonym: Terrasil Jock-Itch Treatment MAX)		1件: Clotrimazole1件: D00282 --1件: 97
16 Dihydrocodeine
(Synonym: Trezix)		0件: 2件: D01481 ,
D07831 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 310
17 Epinephrine
(Synonym: Anakit Insect Sting Treatment Kit)		3件: Epinephrine; Lidocaine; Xylocaine3件: D00095 ,
D00996 ,
D02149 		9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 46, 70, 96
18 Esomeprazole
(Synonym: Berkley and Jensen Heartburn Treatment)		3件: Esomeprazole; Nexium; Omeprazole4件: D01984 ,
D04056 ,
D07917 ,
D09339 		2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299
19 Ethanol
(Synonym: Anti-Bacterial Hand Peppermint and Tea Tree)		3件: Alcohol; Ethanol; Prednisone4件: D00068 ,
D02798 ,
D04855 ,
D06542 		--7件: 13, 51, 58, 97, 279, 280, 298
20 Ginkgo biloba
(Synonym: Maidenhair tree leaf)		3件: Ginkgo; Ginkgo biloba; Tanakan---5件: 6, 13, 18, 47, 90
21 Glycerin
(Synonym: Phyto Therapy Treatment)		3件: Bee venom; Glycerine; Glycerol1件: D00028 --6件: 6, 13, 79, 265, 316, 317
22 Glycine
(Synonym: CAREDO Treating Gingivitis Toothpastes 100g)		1件: Glycine1件: D00011 --5件: 35, 60, 86, 226, 299
23 Guselkumab
(Synonym: Tremfya)		2件: Guselkumab; TREMFYA1件: D10438 (Name: Tremfya (TN))1件: IL23A 💬9件: C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬5件: 37, 41, 51, 96, 97
24 Histidine
(Synonym: Trepoxen-250)		2件: Histidine; L-Histidine1件: D00032 --3件: 13, 169, 170
25 Horse chestnut 1件: Horse chestnut1件: D12028 (Name: Conker tree)--1件: 210
26 Hydrocortisone
(Synonym: Post Treatment Balm)		6件: Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
27 Hydrocortisone acetate
(Synonym: Irritated Skin Treatment)		2件: Hydrocortisone; HYDROCORTISONE ACETATE1件: D00165 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 97
28 Lansoprazole
(Synonym: Rugby Heartburn Treatment)		1件: Lansoprazole1件: D00355 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299
29 Lidocaine
(Synonym: Family Medic First-aid Treatment Lotion)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine3件: D00358 ,
D02086 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
30 Methotrexate
(Synonym: Trexall)		6件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; Metoject; METOTREXATO; Méthotrexate2件: D00142 ,
D02115 (Name: Trexall (TN))		2件: DHFR,
DHFR2 💬		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
31 Minoxidil
(Synonym: Club Roots - Topical Solution Hair Regrowth Treatment)		1件: MINOXIDIL1件: D00418 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬1件: 179
32 Naproxen
(Synonym: Trepoxen-250)		5件: Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid1件: D00118 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 13, 46, 107, 271
33 Nicotinamide
(Synonym: do good Deep Aqua Treatment Toner)		4件: Ginseng; Multivitamin; Niacinamide; NICOTINAMIDE1件: D00036 --11件: 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
34 Olive oil
(Synonym: Intensive Treatment Bodyoil for Mommy To Be All Skin)		1件: Olive Oil1件: D03311 --3件: 13, 49, 53
35 Pentoxifylline
(Synonym: Trental)		1件: Pentoxifylline1件: D00501 (Name: Trental (TN))--10件: 26, 56, 84, 93, 96, 113, 220, 222, 296, 298
36 Petrolatum
(Synonym: Shopko Lip Treatment)		1件: Petrolatum1件: D05331 --3件: 35, 158, 162
37 Phenylephrine
(Synonym: Trexbrom)		1件: Phenylephrine2件: D00511 ,
D08365 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
38 Salicylic acid
(Synonym: Ultra Clear Treatment)		2件: 2-Hydroxybenzoic acid; Salicylic acid1件: D00097 --1件: 97
39 Sodium fluoride
(Synonym: Crest 3D White Whitening Therapy Charcoal with Tea Tree Oil)		2件: Beam; Sodium fluoride1件: D00943 --1件: 51
40 Threonine
(Synonym: Treonina)		1件: Threonine1件: D00041 --3件: 86, 96, 97
41 Thymol
(Synonym: Acne Vanish Synergy for treatment of Acnes)		1件: Thymol1件: D01039 --1件: 13
42 Tregalizumab 1件: Tregalizumab---1件: 46
43 Trehalose 2件: Cabaletta; Trehalose---3件: 2, 18, 113
44 Tremelimumab 1件: Ticilimumab1件: D06657 (Name: Tremelimumab)1件: CTLA4 💬4件: Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬1件: 96
45 Treosulfan 2件: OVASTAT; Treosulfan1件: D07253 (Name: Treosulfan)--6件: 13, 19, 62, 65, 283, 286
46 Treprostinil 4件: Remodulin; Treprostinil; Treprostinilo; Tyvaso1件: D06213 (Name: Treprostinil)1件: PTGIR 💬3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬6件: 51, 84, 85, 86, 88, 210
47 Tretinoin 5件: ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID1件: D00094 (Name: Tretinoin)3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231
48 Triamcinolone
(Synonym: Treziopak)		4件: Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide5件: D00385 ,
D00983 ,
D00984 ,
D00985 ,
D06216 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
49 Triptorelin
(Synonym: Trelstar)		2件: GnRH; TRIPTORELIN1件: D06247 1件: GNRHR 💬2件: GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬2件: 49, 76