Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 TNFSF13B 4件: Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Intestinal immune network for IgA production, Rheumatoid arthritis D03068 Belimumab 12件: 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300
2 CHRM1 8件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases D00765 Rocuronium 1件: 296
3 CHRM2 6件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton D00765 Rocuronium 1件: 296
4 CHRM3 11件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases D00765 Rocuronium 1件: 296
5 CHRM4 3件: Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton D00765 Rocuronium 1件: 296
6 CHRM5 6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases D00765 Rocuronium 1件: 296
7 CHRNA2 1件: Neuroactive ligand-receptor interaction D00765 Rocuronium 1件: 296
8 CHRNA3 3件: Neuroactive ligand-receptor interaction, Cholinergic synapse, Chemical carcinogenesis - receptor activation D00765 Rocuronium 1件: 296
9 CHRNA4 4件: Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation D00765 Rocuronium 1件: 296
10 CHRNA5 1件: Neuroactive ligand-receptor interaction D00765 Rocuronium 1件: 296
11 CHRNA7 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Cholinergic synapse, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Nicotine addiction, Chemical carcinogenesis - receptor activation D00765 Rocuronium 1件: 296
12 CHRNB2 4件: Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction, Chemical carcinogenesis - receptor activation D00765 Rocuronium 1件: 296
13 CHRNB3 1件: Neuroactive ligand-receptor interaction D00765 Rocuronium 1件: 296
14 CHRNB4 3件: Neuroactive ligand-receptor interaction, Cholinergic synapse, Chemical carcinogenesis - receptor activation D00765 Rocuronium 1件: 296
15 CSF3R 5件: Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Hematopoietic cell lineage, Pathways in cancer D03235 Filgrastim 34件: 2, 6, 11, 13, 16, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331
16 ADRB1 11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy D00483 Propranolol 7件: 6, 158, 167, 215, 227, 278, 296
17 ADRB1 11件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy D08443 Propranolol 7件: 6, 158, 167, 215, 227, 278, 296
18 ADRB2 9件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation D00483 Propranolol 7件: 6, 158, 167, 215, 227, 278, 296
19 ADRB2 9件: Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation D08443 Propranolol 7件: 6, 158, 167, 215, 227, 278, 296
20 ADRB3 8件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation D00483 Propranolol 7件: 6, 158, 167, 215, 227, 278, 296
21 ADRB3 8件: Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation D08443 Propranolol 7件: 6, 158, 167, 215, 227, 278, 296
22 GABRA1 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
23 GABRA2 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
24 GABRA3 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
25 GABRA4 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
26 GABRA5 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
27 GABRA6 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
28 GABRB1 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
29 GABRB2 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
30 GABRB3 6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
31 GABRD 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
32 GABRE 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
33 GABRG1 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
34 GABRG2 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
35 GABRG3 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
36 GABRP 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
37 NR3C1 1件: Neuroactive ligand-receptor interaction D00292 Dexamethasone 2件: 296, 299
38 NR3C1 1件: Neuroactive ligand-receptor interaction D00407 Methylprednisolone 2件: 296, 300
39 NR3C1 1件: Neuroactive ligand-receptor interaction D00472 Prednisolone 4件: 296, 299, 300, 307
40 NR3C1 1件: Neuroactive ligand-receptor interaction D00751 Methylprednisolone 2件: 296, 300
41 NR3C1 1件: Neuroactive ligand-receptor interaction D00975 Dexamethasone 2件: 296, 299
42 NR3C1 1件: Neuroactive ligand-receptor interaction D00979 Methylprednisolone 2件: 296, 300
43 NR3C1 1件: Neuroactive ligand-receptor interaction D00980 Prednisolone 4件: 296, 299, 300, 307
44 NR3C1 1件: Neuroactive ligand-receptor interaction D00981 Prednisolone 4件: 296, 299, 300, 307
45 NR3C1 1件: Neuroactive ligand-receptor interaction D00982 Prednisolone 4件: 296, 299, 300, 307
46 NR3C1 1件: Neuroactive ligand-receptor interaction D01239 Prednisolone 4件: 296, 299, 300, 307
47 NR3C1 1件: Neuroactive ligand-receptor interaction D01510 Dexamethasone 2件: 296, 299
48 NR3C1 1件: Neuroactive ligand-receptor interaction D01615 Dexamethasone 2件: 296, 299
49 NR3C1 1件: Neuroactive ligand-receptor interaction D01632 Dexamethasone 2件: 296, 299
50 NR3C1 1件: Neuroactive ligand-receptor interaction D01948 Dexamethasone 2件: 296, 299
51 NR3C1 1件: Neuroactive ligand-receptor interaction D01998 Prednisolone 4件: 296, 299, 300, 307
52 NR3C1 1件: Neuroactive ligand-receptor interaction D02156 Prednisolone 4件: 296, 299, 300, 307
53 NR3C1 1件: Neuroactive ligand-receptor interaction D02174 Dexamethasone 2件: 296, 299
54 NR3C1 1件: Neuroactive ligand-receptor interaction D02591 Dexamethasone 2件: 296, 299
55 NR3C1 1件: Neuroactive ligand-receptor interaction D02592 Dexamethasone 2件: 296, 299
56 NR3C1 1件: Neuroactive ligand-receptor interaction D03301 Prednisolone 4件: 296, 299, 300, 307
57 NR3C1 1件: Neuroactive ligand-receptor interaction D05000 Methylprednisolone 2件: 296, 300
58 NR3C1 1件: Neuroactive ligand-receptor interaction D05001 Methylprednisolone 2件: 296, 300
59 NR3C1 1件: Neuroactive ligand-receptor interaction D05002 Methylprednisolone 2件: 296, 300
60 PPARA 10件: PPAR signaling pathway, cAMP signaling pathway, Adipocytokine signaling pathway, Glucagon signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, Alcoholic liver disease, Hepatitis C, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy D01366 Bezafibrate 7件: 20, 93, 94, 160, 296, 316, 324
61 CHRNA9 2件: Neuroactive ligand-receptor interaction, Chemical carcinogenesis - receptor activation D00765 Rocuronium 1件: 296
62 GABRQ 5件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction D00549 Propofol 10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
63 CHRNA10 1件: Neuroactive ligand-receptor interaction D00765 Rocuronium 1件: 296
64 PTGS2 22件: Arachidonic acid metabolism, Metabolic pathways, NF-kappa B signaling pathway, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer D00969 Meloxicam 4件: 46, 49, 271, 296
65 SLC10A1 2件: Bile secretion, Hepatitis B D10951 Maralixibat 3件: 296, 297, 338
66 SLC10A2 1件: Bile secretion D10951 Maralixibat 3件: 296, 297, 338
67 SLC10A2 1件: Bile secretion D11716 Odevixibat 3件: 296, 297, 338
68 CHRNA6 3件: Neuroactive ligand-receptor interaction, Cholinergic synapse, Nicotine addiction D00765 Rocuronium 1件: 296
69 MS4A1 1件: Hematopoietic cell lineage D02994 Rituximab 3件: 296, 300, 331
70 KEAP1 6件: Ubiquitin mediated proteolysis, Parkinson disease, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis D03846 Dimethyl fumarate 5件: 13, 49, 51, 86, 296
71 NR1H4 1件: Bile secretion D00734 Ursodeoxycholic acid 2件: 296, 299
72 NR1H4 1件: Bile secretion D09360 Obeticholic acid 1件: 296