Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Adherens junction 💬 Related to 9 target genes, 18 drugs (DrugBank) and 24 diseases in DDrare |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 2 | Bladder cancer 💬 Related to 10 target genes, 21 drugs (DrugBank) and 23 diseases in DDrare |
FGFR3 1件: FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 3 | Breast cancer 💬 Related to 21 target genes, 57 drugs (DrugBank) and 71 diseases in DDrare |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 4 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 5 | Central carbon metabolism in cancer 💬 Related to 18 target genes, 26 drugs (DrugBank) and 56 diseases in DDrare |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 6 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
NPR2 1件: NPR2 💬 |
D11190 D11190 💬 |
Vosoritide | 276 1件: 276 💬 |
| 7 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 23件: 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
| 8 | EGFR tyrosine kinase inhibitor resistance 💬 Related to 25 target genes, 50 drugs (DrugBank) and 84 diseases in DDrare |
FGFR2 2件: FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 9 | Endocytosis 💬 Related to 21 target genes, 28 drugs (DrugBank) and 53 diseases in DDrare |
FGFR2 2件: FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 10 | Gastric cancer 💬 Related to 21 target genes, 31 drugs (DrugBank) and 59 diseases in DDrare |
FGFR2 1件: FGFR2 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 11 | Growth hormone synthesis, secretion and action 💬 Related to 23 target genes, 39 drugs (DrugBank) and 85 diseases in DDrare |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 23件: 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
| 12 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 23件: 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
| 13 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 14 | Melanoma 💬 Related to 16 target genes, 26 drugs (DrugBank) and 35 diseases in DDrare |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 15 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
NPR2 1件: NPR2 💬 |
D11190 D11190 💬 |
Vosoritide | 276 1件: 276 💬 |
| 16 | MicroRNAs in cancer 💬 Related to 31 target genes, 62 drugs (DrugBank) and 85 diseases in DDrare |
FGFR3 1件: FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 17 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 328 drugs (DrugBank) and 158 diseases in DDrare |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 23件: 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
| 18 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
NPR2 1件: NPR2 💬 |
D11190 D11190 💬 |
Vosoritide | 276 1件: 276 💬 |
| 19 | Parathyroid hormone synthesis, secretion and action 💬 Related to 20 target genes, 44 drugs (DrugBank) and 64 diseases in DDrare |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 20 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 21 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 22 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 23件: 2 , 3 , 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299 💬 |
| 23 | Prostate cancer 💬 Related to 22 target genes, 48 drugs (DrugBank) and 80 diseases in DDrare |
FGFR1 2件: FGFR1, FGFR2 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 24 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 25 | Purine metabolism 💬 Related to 30 target genes, 35 drugs (DrugBank) and 74 diseases in DDrare |
NPR2 1件: NPR2 💬 |
D11190 D11190 💬 |
Vosoritide | 276 1件: 276 💬 |
| 26 | Rap1 signaling pathway 💬 Related to 42 target genes, 96 drugs (DrugBank) and 85 diseases in DDrare |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 27 | Ras signaling pathway 💬 Related to 35 target genes, 49 drugs (DrugBank) and 61 diseases in DDrare |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 28 | Regulation of actin cytoskeleton 💬 Related to 27 target genes, 54 drugs (DrugBank) and 57 diseases in DDrare |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 29 | Signaling pathways regulating pluripotency of stem cells 💬 Related to 20 target genes, 25 drugs (DrugBank) and 48 diseases in DDrare |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 30 | Thermogenesis 💬 Related to 17 target genes, 28 drugs (DrugBank) and 81 diseases in DDrare |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
| 31 | Vascular smooth muscle contraction 💬 Related to 30 target genes, 76 drugs (DrugBank) and 70 diseases in DDrare |
NPR2 1件: NPR2 💬 |
D11190 D11190 💬 |
Vosoritide | 276 1件: 276 💬 |