Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Autophagy - animal 💬
1件: BCL2 💬 D10679 💬 Venetoclax 1件: 28 💬
2 Autophagy - animal 💬
1件: IGF1R 💬 D09925 💬 Linsitinib 1件: 232 💬
3 Autophagy - animal 💬
1件: IGF1R 💬 D03297 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
4 Autophagy - animal 💬
1件: IGF1R 💬 D04870 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
5 Autophagy - animal 💬
1件: IGF1R 💬 D09680 💬 Teprotumumab 1件: 51 💬
6 Autophagy - animal 💬
2件: MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib 1件: 34 💬
7 Autophagy - animal 💬
2件: MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib 1件: 280 💬
8 Autophagy - animal 💬
2件: MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib 1件: 34 💬
9 Autophagy - animal 💬
2件: MAP2K1, MAP2K2 💬 D10175 💬 Trametinib 4件:  2 , 34, 279, 280 💬
10 Autophagy - animal 💬
1件: MTOR 💬 D02714 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
11 Autophagy - animal 💬
1件: MTOR 💬 D00753 💬 Sirolimus 41件:  2 ,  6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬
12 Autophagy - animal 💬
1件: MTOR 💬 D06068 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
13 Autophagy - animal 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib 2件: 53, 65 💬
14 Autophagy - animal 💬
1件: PIK3CD 💬 D11437 💬 Parsaclisib 3件: 35, 53, 61 💬
15 Autophagy - animal 💬
2件: PRKAA1, PRKAA2 💬 D00944 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
16 Autophagy - animal 💬
2件: PRKAA1, PRKAA2 💬 D04966 💬 Metformin 24件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
17 Autophagy - animal 💬
2件: PRKCD, PRKCQ 💬 D09671 💬 Sotrastaurin 1件: 97 💬
18 Autophagy - animal 💬
1件: RAF1 💬 D06272 💬 Sorafenib 2件: 34, 86 💬
19 Autophagy - animal 💬
1件: RAF1 💬 D08524 💬 Sorafenib 2件: 34, 86 💬