Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D00615 💬 Amlodipine 4件: 13, 51, 67, 298 💬
2 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D02914 💬 Amlodipine 4件: 13, 51, 67, 298 💬
3 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D07450 💬 Amlodipine 4件: 13, 51, 67, 298 💬
4 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D01173 💬 Cilnidipine 1件: 67 💬
5 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D00616 💬 Diltiazem 3件: 51, 58, 86 💬
6 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D03830 💬 Diltiazem 3件: 51, 58, 86 💬
7 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D07845 💬 Diltiazem 3件: 51, 58, 86 💬
8 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D00349 💬 Isradipine 1件:  6  💬
9 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D00617 💬 Nicardipine 2件: 70, 86 💬
10 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D08270 💬 Nicardipine 2件: 70, 86 💬
11 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D00437 💬 Nifedipine 2件: 50, 81 💬
12 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D01908 💬 Nilvadipine 1件: 90 💬
13 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D05442 💬 Perhexiline 2件: 58, 272 💬
14 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D08340 💬 Perhexiline 2件: 58, 272 💬
15 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D08441 💬 Propiverine 1件: 226 💬
16 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D00619 💬 Verapamil 3件: 96, 140, 167 💬
17 Circadian entrainment 💬
2件: CACNA1C, CACNA1D 💬 D02356 💬 Verapamil 3件: 96, 140, 167 💬
18 Circadian entrainment 💬
6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
19 Circadian entrainment 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D01303 💬 Flunarizine 4件: 58, 86, 149, 215 💬
20 Circadian entrainment 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D07971 💬 Flunarizine 4件: 58, 86, 149, 215 💬
21 Circadian entrainment 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D00399 💬 Valproic acid 17件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331 💬
22 Circadian entrainment 💬
3件: CACNA1G, CACNA1H, CACNA1I 💬 D00538 💬 Zonisamide 1件:  6  💬
23 Circadian entrainment 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 D08964 💬 Perampanel 3件:  2 ,  6 , 144 💬
24 Circadian entrainment 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 D02696 💬 Talampanel 2件:  2 ,  6  💬
25 Circadian entrainment 💬
9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
26 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D02780 💬 Acamprosate 2件:  6 , 206 💬
27 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07058 💬 Acamprosate 2件:  6 , 206 💬
28 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00777 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
29 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine 4件:  6 ,  8 , 13, 127 💬
30 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
31 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
32 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
33 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
34 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00711 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
35 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
36 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine 1件:  8  💬
37 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D04905 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
38 Circadian entrainment 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine 7件:  2 ,  6 ,  8 , 13, 49, 127, 205 💬
39 Circadian entrainment 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 D00517 💬 Amyl Nitrite 1件: 58 💬
40 Circadian entrainment 💬
3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 D09572 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬
41 Circadian entrainment 💬
2件: KCNJ3, KCNJ5 💬 D00636 💬 Amiodarone 2件: 28, 127 💬
42 Circadian entrainment 💬
2件: KCNJ3, KCNJ5 💬 D02910 💬 Amiodarone 2件: 28, 127 💬
43 Circadian entrainment 💬
2件: MTNR1A, MTNR1B 💬 D02578 💬 Agomelatine 1件:  6  💬
44 Circadian entrainment 💬
2件: MTNR1A, MTNR1B 💬 D08170 💬 Melatonin 12件:  6 ,  8 , 13, 37, 46, 49, 90, 97, 144, 145, 149, 202 💬
45 Circadian entrainment 💬
2件: MTNR1A, MTNR1B 💬 D02689 💬 Ramelteon 3件:  6 ,  8 , 46 💬
46 Circadian entrainment 💬
2件: MTNR1A, MTNR1B 💬 D09388 💬 Tasimelteon 1件: 202 💬