Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
12-[[[(2R)-1-[1-[(4-CHLORO-3-METHYLPHENYL)METHYL]-4- PIPERIDINYL]-5-OXO-2-PYRROLIDINYL]CARBONYL]AMINO]- N,N,6-TRIMETHYL-4-PYRIDINECARBOXAMIDE,DIHYDROCHLORIDE----[2] 6, 162
2AC-203 1% Topical Ointment----[1] 162
3Acetate[1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
4AKST4290----[2] 6, 162
5Apremilast[1] Apremilast[1] D08860 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[7] 46, 50, 56, 97, 107, 162, 271
6ARAVA[1] Leflunomide[1] D00749 [1] DHODH 💬[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[3] 46, 53, 162
7Avdoralimab[1] Avdoralimab---[1] 162
8Avdoralimab (IPH5401)[1] Avdoralimab---[1] 162
9Azathioprine[1] Azathioprine[2] D00238 ,
D03033 		--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162
10Azathioprine or Mycophenolate mofetil[3] Azathioprine,
Mycophenolate mofetil,
Mycophenolic acid		[6] D00238 ,
D00752 ,
D03033 ,
D05094 ,
D05095 ,
D05096 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 162
11Baricitinib[1] Baricitinib[1] D10308 [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
12Baricitinib 2 MG [Olumiant][1] Baricitinib[1] D10308 [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[1] 162
13Benralizumab[1] Benralizumab[1] D09874 [1] IL5RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[5] 44, 45, 98, 162, 299
14Bertilimumab----[2] 97, 162
15BIV009----[2] 61, 162
16Blood test----[6] 36, 51, 86, 113, 162, 299
17Bone densitometry----[2] 49, 162
18Carboxymethylcellulose[1] Carboxymethylcellulose[1] D07622 --[2] 35, 162
19Carboxymethylcellulose with ionic silver (Aquacel Ag)[2] Carboxymethylcellulose,
Silver		[1] D07622 --[2] 35, 162
20CC----[14] 13, 28, 46, 49, 51, 56, 84, 85, 96, 97, 98, 162, 202, 271
21CC-10004----[5] 46, 56, 97, 162, 271
22Cellcept® in autoimmune bullous dermatoses----[2] 35, 162
23Cellulose[1] Microcrystalline cellulose[1] D00093 --[4] 35, 53, 96, 162
24Cellulose acetate with petrolatum[3] Acetate,
Microcrystalline cellulose,
Petrolatum		[2] D00093 ,
D05331 		--[2] 35, 162
25Clobetasol[1] Clobetasol[1] D07715 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[4] 39, 46, 51, 162
26Clobetasol 0.05% Topical Ointment[1] Clobetasol[1] D07715 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 162
27Clobetasol Propionate[2] Clobetasol,
Clobetasol propionate		[2] D01272 ,
D07715 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 46, 162
28Clobetasol propionate + Methotrexate[3] Clobetasol,
Clobetasol propionate,
Methotrexate		[4] D00142 ,
D01272 ,
D02115 ,
D07715 		[3] DHFR,
DHFR2,
NR3C1 💬		[6] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Neuroactive ligand-receptor interaction, One carbon pool by folate 💬[1] 162
29Clobetasol propionate alone[2] Clobetasol,
Clobetasol propionate		[2] D01272 ,
D07715 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 162
30Clobetasol Propionate cream treatment[2] Clobetasol,
Clobetasol propionate		[2] D01272 ,
D07715 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 162
31Collagenase[1] Collagenase clostridium histolyticum[1] D09596 --[1] 162
32Cortancyl[1] Prednisone acetate[1] D08416 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[3] 35, 41, 162
33CORTANCYL 20 mg[1] Prednisone acetate[1] D08416 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 35, 162
34Cotton[1] Cotton---[2] 35, 162
35Cotton gauze with petrolatum[2] Cotton,
Petrolatum		[1] D05331 --[2] 35, 162
36Cultivated oral mucosal epithelial sheet transplantation----[2] 38, 162
37Cyclophosphamide[1] Cyclophosphamide[2] D00287 ,
D07760 		--[45] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
38Cyclophosphamide 50Mg Oral Tablet[1] Cyclophosphamide[2] D00287 ,
D07760 		--[1] 162
39Cyclosporine[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
40Dapsone[1] Dapsone[1] D00592 --[5] 35, 42, 60, 84, 162
41Data report----[1] 162
42Dermoval----[2] 35, 162
43Dexamethasone[1] Dexamethasone[9] D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[25] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
44Dexamethasone 0.5mg/5ml solution[1] Dexamethasone[9] D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 35, 162
45Dexamethasone 0.5mg/5ml solution in Mucolox™[1] Dexamethasone[9] D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 35, 162
46DF2156A----[1] 162
47Doxycycline[1] Doxycycline[5] D00307 ,
D02129 ,
D03903 ,
D03904 ,
D07876 		--[16] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
48Dupilumab[1] Dupilumab[1] D10354 [1] IL4R 💬[8] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[4] 51, 98, 160, 162
49Dupixent[1] Dupilumab[1] D10354 [1] IL4R 💬[8] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[3] 98, 160, 162
50EFG PH20 SC----[1] 162
51Fasenra[1] Benralizumab[1] D09874 [1] IL5RA 💬[4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[5] 44, 45, 98, 162, 299
52Gold[1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318
53Halometasone[1] Halometasone[1] D07202 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 162
54Imatinib[1] Imatinib[2] D01441 ,
D08066 		[3] ABL1,
KIT,
PDGFRA 💬		[32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
55Impedance analysis----[1] 162
56Infliximab[1] Infliximab[1] D02598 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[26] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
57INTERLEUKIN-2[1] Human interleukin-2---[8] 2, 35, 49, 55, 65, 96, 97, 162
58IPH5401----[1] 162
59Ixekizumab[1] Ixekizumab[1] D10071 [1] IL17A 💬[6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[6] 36, 37, 107, 162, 269, 271
60Ladarixin[1] Ladarixin---[1] 162
61Large dose of prednisolone plus intra-lesional of Triamcinolone Acetonide followed the systemic combination of mycophenolate mofetil (MMF), dapsone and low dose prednisolone in treatment of MMP[5] Dapsone,
Mycophenolate mofetil,
Mycophenolic acid,
Prednisolone,
Triamcinolone		[18] D00385 ,
D00472 ,
D00592 ,
D00752 ,
D00980 ,
D00981 ,
D00982 ,
D00983 ,
D00984 ,
D00985 ,
D01239 ,
D01998 ,
D02156 ,
D03301 ,
D05094 ,
D05095 ,
D05096 ,
D06216 		[3] IMPDH1,
IMPDH2,
NR3C1 💬		[4] Drug metabolism - other enzymes, Metabolic pathways, Neuroactive ligand-receptor interaction, Purine metabolism 💬[1] 162
62Leflunomide[1] Leflunomide[1] D00749 [1] DHODH 💬[3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[12] 11, 40, 46, 49, 53, 66, 107, 162, 224, 270, 271, 300
63MabThera[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[22] 11, 13, 14, 19, 35, 43, 44, 46, 49, 50, 51, 52, 53, 61, 63, 64, 65, 83, 93, 162, 222, 271
64Mabthéra----[2] 35, 162
65Mathéra----[2] 35, 162
66MEDI-563----[5] 44, 45, 98, 162, 299
67Medrone----[4] 46, 51, 83, 162
68MEPOLIZUMAB[1] Mepolizumab[1] D04923 [1] IL5 💬[13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[4] 44, 45, 98, 162
69Mepolizumab (a-IL-5 antibody)[1] Mepolizumab[1] D04923 [1] IL5 💬[13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[1] 162
70Methotrexate[1] Methotrexate[2] D00142 ,
D02115 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
71Methylprednisolone[1] Methylprednisolone[6] D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
72Minocycline[1] Minocycline[2] D00850 ,
D05045 		--[13] 2, 6, 8, 13, 46, 85, 90, 94, 162, 201, 206, 280, 299
73MMF----[15] 13, 35, 40, 46, 49, 50, 51, 60, 65, 66, 162, 222, 224, 226, 299
74Mometasone[1] Mometasone[3] D00690 ,
D03325 ,
D08227 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 98, 162
75MOMETASONE FUROATE[2] Mometasone,
Mometasone furoate		[3] D00690 ,
D03325 ,
D08227 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 98, 162
76MTX----[14] 13, 35, 40, 46, 49, 50, 51, 60, 84, 96, 97, 107, 162, 271
77Mycophenolate[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
78Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[4] D00752 ,
D05094 ,
D05095 ,
D05096 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
79Myfortic[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[5] 49, 66, 162, 222, 228
80Myfortic 180 mg[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 162
81Myfortic 180 mg Filmtabletten[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[1] 162
82Nanocrystalline silver (Acticoat)[1] Silver---[2] 35, 162
83Nicotinamide[1] Nicotinamide[1] D00036 --[8] 2, 6, 18, 49, 65, 107, 162, 191
84NNC0215-0384----[2] 46, 162
85NOMACOPAN[1] Nomacopan[1] D11473 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 162
86Nomacopan (rVA576)[1] Nomacopan[1] D11473 [1] C5 💬[10] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 162
87NPB-01----[3] 13, 14, 162
88OMALIZUMAB[1] Omalizumab[1] D05251 [1] FCER1A 💬[4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299
89Oral corticosteroids (OCS)----[1] 162
90Otezla[1] Apremilast[1] D08860 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[3] 56, 107, 162
91Other: Blood sample and cotton skin swabs[1] Cotton---[1] 162
92Other: Control----[9] 6, 19, 67, 70, 75, 85, 97, 162, 193
93Other: PBO----[1] 162
94Petrolatum[1] Petrolatum[1] D05331 --[3] 35, 158, 162
95PREDNISOLONE[1] Prednisolone[8] D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[43] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
96Prednisone[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
97QGE031----[1] 162
98Radiographs of the thoracic and lumbar spine----[1] 162
99Restasis----[2] 53, 162
100Riboflavin[1] Riboflavin[3] D00050 ,
D01622 ,
D01913 		--[8] 13, 38, 46, 96, 97, 162, 168, 265
101Rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[49] 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
102Rituximab 1g IV[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 162
103Rituximab combined with Omalizumab[2] Omalizumab,
Rituximab		[2] D02994 ,
D05251 		[2] FCER1A,
MS4A1 💬		[5] Asthma, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[1] 162
104RVA576----[3] 62, 109, 162
105Silver[1] Silver---[2] 35, 162
106Simvastatin[1] Simvastatin[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
107Simvastatin-ratiopharm[1] Simvastatin[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 162
108Simvastatin-ratiopharm®[1] Simvastatin[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 162
109Solu-Medrone----[3] 51, 83, 162
110Tildrakizumab[1] Tildrakizumab[1] D10400 [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[2] 162, 271
111Tildrakizumab Prefilled Syringe[1] Tildrakizumab[1] D10400 [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[1] 162
112Topical infliximab[1] Infliximab[1] D02598 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[3] 38, 39, 162
113Treatment systemic therapy (prednisone)[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 162
114Treatment with systemic therapy (doxycycline)[1] Doxycycline[5] D00307 ,
D02129 ,
D03903 ,
D03904 ,
D07876 		--[1] 162
115Treatment with systemic therapy (methotrexate)[1] Methotrexate[2] D00142 ,
D02115 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 162
116Treatment with systemic therapy (prednisone)[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 162
117Treatment with topical superpotent corticosteroid therapy----[1] 162
118Triamcinolone[1] Triamcinolone[5] D00385 ,
D00983 ,
D00984 ,
D00985 ,
D06216 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
119Tripterygium[1] Tripterygium wilfordii whole---[8] 46, 66, 67, 96, 162, 222, 224, 271
120Ustekinumab[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271