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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
15-[4-[2-(5-(1-hydroxyethyl)-2- pyridinyl)ethoxy]benzyl]-2,4- thiazolidinedione hydrochloride[1] 2,4-thiazolidinedione---[1] 20
25-[4-[2-(5-(1-hydroxyethyl)-2-pyridinyl)ethoxy]benzyl]-2,4-thiazolidinedione hydrochloride[1] 2,4-thiazolidinedione---[1] 20
35-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY]PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE HYDROCHLORIDE[1] 2,4-thiazolidinedione---[1] 20
4Acetylcysteine[1] Acetylcysteine[1] D00221 --[20] 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
5Albumin----[3] 2, 20, 51
6Albumin solution----[1] 20
7Albunorm® 5%,----[1] 20
8ALEMTUZUMAB[1] Alemtuzumab[1] D02802 [1] CD52 💬-[17] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284
9Allogeneic stem cell transplantation----[5] 19, 20, 49, 62, 84
10AUTOLOGOUS CD34+ CELLS TRANSDUCED WITH LENTI-D VECTOR ENCODING ABCD1 CDNA----[1] 20
11Autologous haematopoietic stem cells transduced with lentiviral vector Lenti-D encoding the human ABCD1 cDNA----[1] 20
12Bezafibrate[1] Bezafibrate[1] D01366 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[7] 20, 93, 94, 160, 296, 316, 324
13BIOTIN[1] Biotin[1] D00029 --[5] 2, 8, 10, 13, 20
14Busulfan[1] Busulfan[1] D00248 --[13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326
15Busulfan, Cyclophosphamide, Antithymocyte Globulin[2] Busulfan,
Cyclophosphamide		[3] D00248 ,
D00287 ,
D07760 		--[2] 19, 20
16CALD HR-D (High-Risk, Regimen C)----[5] 19, 20, 125, 234, 326
17CALD HR-D (High-Risk, Regimen D)----[5] 19, 20, 125, 234, 326
18CALD SR-A (Standard-Risk, Regimen A)----[5] 19, 20, 125, 234, 326
19CALD SR-B (Standard-Risk, Regimen B)----[5] 19, 20, 125, 234, 326
20Campath[1] Alemtuzumab[1] D02802 [1] CD52 💬-[12] 19, 20, 49, 51, 60, 62, 65, 164, 234, 283, 285, 326
21Campath-1H[1] Alemtuzumab[1] D02802 [1] CD52 💬-[6] 19, 20, 60, 234, 285, 326
22Chenodeoxycholic acid[1] Chenodeoxycholic acid[1] D00163 [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 96, 234, 263
23Cholic Acid[1] Cholic Acid[1] D10699 [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 234, 265, 310
24Cholic Acids----[2] 20, 234
25Clofarabine[1] Clofarabine[1] D03546 [3] POLA1,
POLA2,
RRM1 💬		[6] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[9] 19, 20, 40, 46, 49, 60, 96, 234, 326
26Cyclophosphamide[1] Cyclophosphamide[2] D00287 ,
D07760 		--[45] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
27Cyclosporine[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
28Cyclosporine A[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[11] 19, 20, 36, 49, 50, 53, 58, 60, 107, 234, 283
29D-BIOTIN[1] Biotin[1] D00029 --[3] 10, 13, 20
30DUOC-01----[3] 13, 19, 20
31Elivaldogene autotemcel[1] Elivaldogene autotemcel[1] D12150 [1] ABCD1 💬[2] ABC transporters, Peroxisome 💬[1] 20
32Elivaldogenum tavalentivecum----[1] 20
33Glyceryl Trierucate[1] Glyceryl Trierucate---[1] 20
34Glyceryl trierucate/glyceryl trioleate[2] Glyceryl Trierucate,
Glyceryl Trioleate		---[1] 20
35Glyceryl Trioleate[1] Glyceryl Trioleate---[1] 20
36Hematopoietic stem cell infusion----[2] 19, 20
37Hematopoietic Stem Cell Transplantation----[13] 11, 13, 14, 19, 20, 35, 46, 49, 51, 65, 96, 234, 285
38Human Placental Derived Stem Cell----[4] 19, 20, 60, 284
39Hydroxyurea[1] Hydroxyurea[1] D00341 [1] RRM2 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284
40IMD----[5] 19, 20, 125, 234, 326
41IMD Preparative Regimen----[5] 19, 20, 125, 234, 326
42Interferon Beta[1] Human interferon beta---[6] 13, 20, 26, 50, 96, 97
43Lenti-D Drug Product----[1] 20
44Leriglitazone[1] Leriglitazone[1] D11603 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 20
45Lipoic acid[1] Lipoic acid[2] D00048 ,
D00086 		--[5] 2, 5, 13, 14, 20
46Lorenzo's Oil----[1] 20
47MD1003----[5] 2, 10, 13, 14, 20
48MD1003 100 mg capsule----[1] 20
49Melphalan[1] Melphalan[1] D00369 --[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299
50Mesenchymal stem cells----[11] 2, 6, 13, 20, 49, 51, 60, 96, 222, 274, 299
51MIN-102----[2] 18, 20
52Modified cobratoxin----[1] 20
53Mycophenolate[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
54Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[4] D00752 ,
D05094 ,
D05095 ,
D05096 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
55Mycophenylate mofetil----[2] 19, 20
56N-Acetylcysteine[1] Acetylcysteine[1] D00221 --[11] 6, 13, 19, 20, 49, 58, 85, 111, 164, 299, 337
57NV1205----[1] 20
58Osteopetrosis Haploidentical Only Preparative Regimen----[5] 19, 20, 125, 234, 326
59Osteopetrosis Only Preparative Regimen----[5] 19, 20, 125, 234, 326
60Pioglitazone[1] Pioglitazone[2] D00945 ,
D08378 		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
61PLERIXAFOR[1] Plerixafor[1] D08971 [1] CXCR4 💬[12] Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral protein interaction with cytokine and cytokine receptor 💬[5] 20, 51, 65, 285, 299
62Pramipexole[1] Pramipexole[2] D00559 ,
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20
63PXL065----[1] 20
64PXL770----[1] 20
65QTXEW2-04-AF, EW2, GC-1, QRX-431----[1] 20
66RPI78M for injection----[1] 20
67Sobetirome[1] Sobetirome[1] D09381 [1] THRB 💬[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[1] 20
68Sobetirome (NV1205)[1] Sobetirome[1] D09381 [1] THRB 💬[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[1] 20
69Stem Cell Transplant----[6] 19, 20, 60, 65, 164, 284
70Stem Cell Transplantation----[13] 13, 19, 20, 46, 51, 60, 62, 65, 90, 125, 164, 234, 326
71Thalidomide[1] Thalidomide[1] D00754 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
72Thiazolidinedione[1] 2,4-thiazolidinedione---[1] 20
73Thiotepa[1] Thiotepa[1] D00583 --[12] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285
74Thiotepa--escalated dose[1] Thiotepa[1] D00583 --[4] 19, 20, 65, 284
75Thiotepa--single daily dose[1] Thiotepa[1] D00583 --[4] 19, 20, 65, 284
76Total body Irradiation----[6] 19, 20, 51, 60, 65, 285
77Ursodiol[1] Ursodeoxycholic acid[1] D00734 [1] NR1H4 💬[1] Bile secretion 💬[6] 8, 20, 93, 97, 234, 299
78Vitamin D3[1] Cholecalciferol[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[12] 6, 13, 20, 46, 49, 51, 53, 60, 65, 96, 97, 299
79Vitamin E[1] Vitamin E[1] D02331 --[11] 2, 6, 13, 20, 46, 90, 96, 97, 206, 299, 317
80VK0214----[1] 20