Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
111C-flumazenil[1] Flumazenil[1] D00697 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 206
218F-FTC-146----[1] 206
35-Hydroxytryptophan / Vitamin B6[1] Pyridoxine[2] D02179 ,
D08454 		--[1] 206
4[18F]flumazenil[1] Flumazenil[1] D00697 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 206
5[18F]FPEB----[3] 6, 8, 206
6[18F]FPEB PET imaging----[1] 206
7Acamprosate[1] Acamprosate[2] D02780 ,
D07058 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 6, 206
8Acetate[1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
9Acidum ascorbicum[1] Ascorbic acid[1] D00018 --[1] 206
10ACIDUM ASCORBICUM D6[1] Ascorbic acid[1] D00018 --[1] 206
11AF056----[1] 206
12AFQ056----[3] 6, 8, 206
13Alpha-tocopherol[2] Tocopherol,
Vitamin E		[2] D02331 ,
D02332 		--[2] 49, 206
14Ampalex----[1] 206
15Arbaclofen[1] Arbaclofen[1] D09791 [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[2] 13, 206
16Aripiprazole[1] Aripiprazole[1] D01164 [4] DRD2,
DRD3,
HTR1A,
HTR2A 💬		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 206
17Ascorbic acid[1] Ascorbic acid[1] D00018 --[4] 10, 97, 206, 298
18Ascorbic Acid (Vitamin C) and Alpha-tocopherol (Vitamin E)[3] Ascorbic acid,
Tocopherol,
Vitamin E		[3] D00018 ,
D02331 ,
D02332 		--[1] 206
19AZD7325----[1] 206
20AZD7325 (High-Dose)----[1] 206
21AZD7325 (Low-Dose)----[1] 206
22Baclofen[1] Baclofen[1] D00241 [2] GABBR1,
GABBR2 💬		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[7] 2, 10, 13, 18, 65, 149, 206
23BPN14770----[1] 206
24Cannabidiol[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[18] 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
25CBD----[12] 2, 6, 8, 13, 36, 46, 140, 144, 145, 156, 158, 206
26CCD 1042, MD 9150000, Mepalon 1042, SPT316----[2] 152, 206
27CX516[1] CX516---[1] 206
28CX516 (Ampalex®)[1] CX516---[1] 206
29Donepezil[1] Donepezil[2] D00670 ,
D07869 		[1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206
30EGCG[1] Epigallocatechin gallate---[9] 6, 8, 13, 17, 28, 85, 113, 206, 299
31EGCG FontUp[1] Epigallocatechin gallate---[1] 206
32Ergoloid Mesylate[1] Ergoloid mesylate[1] D02268 [6] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 206
33Flumazenil[1] Flumazenil[1] D00697 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206
34Fluoxetin[1] Fluoxetine[2] D00326 ,
D00823 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 13, 179, 206
35Gaboxadol[1] Gaboxadol[1] D04282 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 201, 206
36Ganaxolone[1] Ganaxolone[1] D04300 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[4] 145, 152, 158, 206
37Lovastatin[1] Lovastatin[1] D00359 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
38Lovastatin, then Minocycline/Lovastatin[2] Lovastatin,
Minocycline		[3] D00359 ,
D00850 ,
D05045 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 206
39Mavoglurant[1] Mavoglurant---[2] 6, 206
40Metformin[1] Metformin[2] D00944 ,
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
41Methylphenidate[1] Methylphenidate[2] D01296 ,
D04999 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206
42Methylphenidate, fluoxetin, risperidone[3] Fluoxetine,
Methylphenidate,
Risperidone		[5] D00326 ,
D00426 ,
D00823 ,
D01296 ,
D04999 		[5] DRD2,
HTR2A,
SLC6A2,
SLC6A3,
SLC6A4 💬		[14] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Serotonergic synapse, Synaptic vesicle cycle, cAMP signaling pathway 💬[2] 179, 206
43MG01CI extended-release tablet[1] Manganese citrate---[1] 206
44MGlu5 antagonist----[1] 206
45Minocycline[1] Minocycline[2] D00850 ,
D05045 		--[13] 2, 6, 8, 13, 46, 85, 90, 94, 162, 201, 206, 280, 299
46Minocycline Hydrochloride[1] Minocycline[2] D00850 ,
D05045 		--[4] 13, 201, 206, 299
47Minocycline, then Minocycline/Lovastatin[2] Lovastatin,
Minocycline		[3] D00359 ,
D00850 ,
D05045 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 206
48NNZ-2566----[2] 156, 206
49NPL-2009----[1] 206
50Other: Biological samples----[1] 206
51Other: Cognitive training----[1] 206
52Other: Language Intervention----[1] 206
53Other: MRI----[3] 6, 127, 206
54OV101----[2] 201, 206
55OV101 (gaboxadol)[1] Gaboxadol[1] D04282 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 206
56Oxytocin[1] Oxytocin[1] D00089 [1] OXTR 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[6] 6, 72, 127, 193, 206, 226
57Oxytocin 24IU[1] Oxytocin[1] D00089 [1] OXTR 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[1] 206
58Oxytocin 48IU[1] Oxytocin[1] D00089 [1] OXTR 💬[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[1] 206
59Release[1] Manganese citrate---[12] 6, 8, 13, 46, 65, 78, 81, 96, 97, 206, 226, 299
60RILUZOLE[1] Riluzole[1] D00775 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206
61Risperidone[1] Risperidone[1] D00426 [2] DRD2,
HTR2A 💬		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[5] 8, 156, 179, 187, 206
62Ro 491-7523/F18----[1] 206
63Ro 491-7523/F19----[1] 206
64RO4917523----[1] 206
65RO4917523 0.5 mg----[1] 206
66RO4917523 1.5 mg----[1] 206
67Sertraline[1] Sertraline[2] D00825 ,
D02360 		[1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 206
68STX107----[1] 206
69STX209----[1] 206
70Sugar pill----[8] 5, 6, 49, 67, 70, 86, 206, 210
71Sulindac[1] Sulindac[1] D00120 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 206
72Sulindac, dose strength 1[1] Sulindac[1] D00120 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 206
73Sulindac, dose strength 2[1] Sulindac[1] D00120 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 206
74Tocopherol[1] Tocopherol[1] D02332 --[5] 13, 49, 206, 257, 298
75TOCOPHERYL ACETATE[2] Acetate,
alpha-Tocopherol acetate		---[1] 206
76Vitamin B6[1] Pyridoxine[2] D02179 ,
D08454 		--[2] 6, 206
77Vitamin C[1] Ascorbic acid[1] D00018 --[6] 10, 192, 206, 210, 211, 212
78Vitamin C 10mg/Kg Vitamin E 10 mg/Kg[2] Ascorbic acid,
Vitamin E		[2] D00018 ,
D02331 		--[1] 206
79Vitamin E[1] Vitamin E[1] D02331 --[11] 2, 6, 13, 20, 46, 90, 96, 97, 206, 299, 317
80Zatolmilast----[1] 206
81ZYN002----[2] 203, 206
82ZYN002 - CBD Transdermal Gel----[1] 206
83ZYN002 - transdermal gel----[1] 206