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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1A042917017----[1] 21
2Alpha-tocotrienol quinone[1] Tocotrienol---[2] 21, 156
3Bupropion[1] Bupropion[3] D00817 ,
D07591 ,
D07938 		[2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
4Caffeine[1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 2, 6, 13, 21, 46, 78, 96, 97, 265
5CoenzymeQ10----[1] 21
6Creatine[1] Creatine---[16] 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 113, 156, 201, 256
7Cysteamine[1] Cysteamine[2] D03634 ,
D03635 		--[4] 8, 19, 21, 299
8Cysteamine Bitartrate[1] Cysteamine[2] D03634 ,
D03635 		--[4] 8, 19, 21, 299
9DEXMEDETOMIDINE[1] Dexmedetomidine[2] D00514 ,
D01205 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[13] 2, 4, 6, 21, 34, 46, 70, 107, 113, 212, 215, 226, 280
10Dextromethorphan[1] Dextromethorphan[3] D00848 ,
D03742 ,
D03744 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
11Diagnostic Test: Creatine Chemical Exchange Saturation Transfer (CrCEST) Imaging Sequence[1] Creatine---[1] 21
12ELAMIPRETIDE[1] Elamipretide[1] D10925 --[2] 21, 324
13Elamipretide (high dose)[1] Elamipretide[1] D10925 --[1] 21
14Elamipretide (intermediate dose)[1] Elamipretide[1] D10925 --[1] 21
15Elamipretide (low dose)[1] Elamipretide[1] D10925 --[1] 21
16EPI-743----[3] 21, 156, 337
17EPI743----[1] 21
18Feburane----[1] 21
19FLURBIPROFEN[1] Flurbiprofen[3] D00330 ,
D01475 ,
D02290 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46
20Fluzone[1] Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated)---[2] 21, 49
21Fluzone®[1] Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated)---[1] 21
22KH176----[1] 21
23KL1333----[1] 21
24Low Residue Diet Intervention----[1] 21
25Midazolam[1] Midazolam[3] D00550 ,
D00696 ,
D05028 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
26Midazolam injection[1] Midazolam[3] D00550 ,
D00696 ,
D05028 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 21
27MTP-131----[1] 21
28Omeprazole[1] Omeprazole[4] D00455 ,
D01207 ,
D05259 ,
D05261 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
29Pheburane[1] Phenylbutyric acid---[1] 21
30PROPOFOL[1] Propofol[1] D00549 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[9] 6, 21, 22, 34, 46, 70, 84, 98, 296
31PTC743----[2] 18, 21
32Reagila[1] Cariprazine[1] D09997 [3] DRD2,
HTR1A,
HTR2A 💬		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 21
33Repaglinide[1] Repaglinide[1] D00594 [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[3] 6, 21, 299
34RG2133 (2',3',5'-tri-O-acetyluridine)[1] Uridine triacetate[1] D09985 --[1] 21
35Sevoflurane[1] Sevoflurane[1] D00547 --[7] 6, 21, 22, 34, 98, 225, 296
36Sonlicromanol[1] Sonlicromanol---[1] 21
37SPP-004----[1] 21
38Tocotrienol[1] Tocotrienol---[3] 21, 156, 299
39Tri-O-acetyluridine[1] Uridine triacetate[1] D09985 --[1] 21
40VATIQUINONE[1] Vatiquinone[1] D10407 --[2] 18, 21