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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
100244301----[1] 274
2Aclasta----[3] 13, 271, 274
3Actonel 5mg Film Coated Tablets[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
4Actonel Once a Week 35 mg film-coated tablets[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
5Actonel/Optinate 5mg film-coated tablets[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
6Alendronate[1] Alendronic acid[2] D00939 ,
D07119
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 19, 41, 46, 50, 271, 274, 299
7ALENDRONIC ACID[1] Alendronic acid[2] D00939 ,
D07119
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[2] 46, 274
8Alternative osteoporosis medications----[1] 274
9AMG 162----[2] 46, 274
10AMG 785----[1] 274
11ANTI-SCLEROSTIN MONOCLONAL ANTIBODY----[1] 274
12Bisphosphonates----[2] 6, 274
13Blood sample----[18] 8, 13, 46, 49, 51, 53, 61, 65, 66, 84, 96, 97, 107, 127, 235, 274, 288, 299
14Bone Marrow Transplant----[2] 60, 274
15Bonefos[1] Clodronic acid[2] D03544 ,
D03545
--[1] 274
16BOOST cells----[1] 274
17BPS804----[2] 172, 274
18Busulfan[1] Busulfan[1] D00248 --[13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326
19Calcichew D3----[1] 274
20Calcichew tablets----[1] 274
21Calcio[1] Calcium---[4] 13, 96, 97, 274
22Calcio carbonato[2] Calcium,
Calcium carbonate
[2] D00932 ,
D10802
--[1] 274
23CALCIO CARBONATO/COLECALCIFEROLO[2] Calcium,
Calcium carbonate
[2] D00932 ,
D10802
--[1] 274
24Calcium[1] Calcium---[30] 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
25Calcium D3[1] Calcium---[1] 274
26CALCIUM D3 SANDOZ - 1000 MG + 880 U.I. COMPRESSE EFFERVESCENTI 30 COMPRESSE DIVISIBILI[1] Calcium---[1] 274
27Celulas madre mesenquimales troncales adultas alogenicas de médula ósea no expandida----[1] 274
28Clasteon[1] Clodronic acid[2] D03544 ,
D03545
--[1] 274
29Cyclophosphamide[1] Cyclophosphamide[2] D00287 ,
D07760
--[45] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
30Cyclosporin[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[17] 38, 46, 49, 50, 53, 56, 60, 62, 63, 93, 95, 97, 113, 164, 222, 274, 326
31Células mesenquimales troncales adultas alogénicas de médula ósea no expandidas----[1] 274
32Células mesenquimales troncales adultas alogénicas de médula ósea no expandidas(ref cruzada PEI nº 12-088)----[1] 274
33Denosumab[1] Denosumab[1] D03684 [1] TNFSF11 💬[8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[7] 46, 50, 93, 95, 96, 274, 299
34Denosumab - - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand[1] Denosumab[1] D03684 [1] TNFSF11 💬[8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[1] 274
35Denosumab - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand[1] Denosumab[1] D03684 [1] TNFSF11 💬[8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[1] 274
36Denusomab----[1] 274
37Disodium Pamidronate 15mg (15mg strength)[1] Pamidronic acid[2] D00941 ,
D07281
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
38Evenity[1] Romosozumab[1] D10156 [1] SOST 💬[2] Parathyroid hormone synthesis, secretion and action, Wnt signaling pathway 💬[1] 274
39Evenity 105mg[1] Romosozumab[1] D10156 [1] SOST 💬[2] Parathyroid hormone synthesis, secretion and action, Wnt signaling pathway 💬[1] 274
40Expanded human first trimester fetal liver-derived mesenchymal stem cells----[1] 274
41Forsteo[1] Teriparatide[1] D06078 [1] PTH1R 💬[3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬[3] 70, 235, 274
42Fresolimumab[1] Fresolimumab[1] D09620 [3] TGFB1,
TGFB2,
TGFB3 💬
[35] AGE-RAGE signaling pathway in diabetic complications, Amoebiasis, Cell cycle, Cellular senescence, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Diabetic cardiomyopathy, Dilated cardiomyopathy, FoxO signaling pathway, Gastric cancer, Hepatitis B, Hepatocellular carcinoma, Hippo signaling pathway, Human T-cell leukemia virus 1 infection, Hypertrophic cardiomyopathy, Inflammatory bowel disease, Intestinal immune network for IgA production, Leishmaniasis, MAPK signaling pathway, Malaria, MicroRNAs in cancer, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, TGF-beta signaling pathway, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[3] 51, 222, 274
43Fultium-D3 800IU capsules----[1] 274
44GENOTROPIN*1TBF 5,3MG (16UI)[1] Somatotropin[1] D02691 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[1] 274
45H05AA02----[1] 274
46High-dose vitamin D (2000 IU per day)[1] Vitamin D---[1] 274
47Humatrope----[2] 78, 274
48Ibandronic acid[1] Ibandronate[1] D08056 [1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
49Mesenchymal stem cell transplantation----[2] 36, 274
50Mesenchymal stem cells----[11] 2, 6, 13, 20, 49, 51, 60, 96, 222, 274, 299
51Mesenchymal Stromal Cells[1] Human Umbilical Cord Mesenchymal Stem Cells---[10] 2, 36, 49, 51, 60, 96, 97, 107, 274, 284
52NERIXIA*INFUS IV CONC 2F 100MG----[1] 274
53Optinate 5 mg filmcoated tablets----[1] 274
54Other: Bone Marrow Cell Transplantation----[1] 274
55Other: No active treatment----[1] 274
56Other: No treatment----[2] 53, 274
57Other: Saline----[8] 2, 6, 46, 97, 98, 256, 274, 301
58Pamidronate[1] Pamidronic acid[2] D00941 ,
D07281
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 270, 271, 274
59Pamidronate (Aredia)[1] Pamidronic acid[2] D00941 ,
D07281
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
60PLASMASAFE----[1] 274
61PLASMASAFE - SOLUZIONE PER INFUSIONE 1 SACCA DA 200 ML----[1] 274
62Prolia[1] Denosumab[1] D03684 [1] TNFSF11 💬[8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[1] 274
63Radiation: Irradiation, Total Body----[1] 274
64REF CRUZADA PEI Nº 12-088----[1] 274
65Risedronate[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[7] 46, 50, 66, 96, 107, 113, 274
66Risedronate Oral Tablet[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
67RISEDRONATE SODIUM[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[4] 50, 107, 113, 274
68Risedronate sodium (Actonel)[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
69Risedronate sodium 2.5mg[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
70Risedronate sodium 5mg[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
71Risedronato sódico 2.5mg----[1] 274
72Risedronato sódico 5mg----[1] 274
73Risedronic acid[1] Risedronic acid[3] D00942 ,
D03234 ,
D08484
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 93, 95, 274
74Rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[49] 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
75ROMOSOZUMAB[1] Romosozumab[1] D10156 [1] SOST 💬[2] Parathyroid hormone synthesis, secretion and action, Wnt signaling pathway 💬[1] 274
76SAR439459----[1] 274
77Setrusumab[1] Setrusumab---[1] 274
78Somatropin[1] Somatotropin[1] D02691 [1] GHR 💬[5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬[19] 2, 3, 19, 46, 65, 74, 75, 78, 96, 107, 113, 187, 193, 195, 238, 265, 274, 276, 299
79Standard-dose vitamin D (400IU per day)[1] Vitamin D---[1] 274
80Teriparatide[1] Teriparatide[1] D06078 [1] PTH1R 💬[3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬[6] 46, 68, 70, 71, 235, 274
81Teriparatide (FORTEO)[1] Teriparatide[1] D06078 [1] PTH1R 💬[3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬[1] 274
82Teriparatide Pen Injector[1] Teriparatide[1] D06078 [1] PTH1R 💬[3] Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬[1] 274
83VARI----[2] 62, 274
84Vitamin D[1] Vitamin D---[24] 3, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299
85Vitamina D e calcio[1] Calcium---[1] 274
86XGEVA[1] Denosumab[1] D03684 [1] TNFSF11 💬[8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[1] 274
87XGEVA - 120 MG - SOLUZIONE INIETTABILE - USO SOTTOCUTANEO - FLACONCINO (VETRO) - 1.7 ML 4 FLACONCINI[1] Denosumab[1] D03684 [1] TNFSF11 💬[8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[1] 274
88ZOL446----[1] 274
89Zoledronic acid[1] Zoledronic acid[4] D01968 ,
D06378 ,
D06379 ,
D08689
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[12] 5, 6, 13, 17, 46, 93, 95, 96, 270, 274, 299, 333
90Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion, generic medicinal product[1] Zoledronic acid[4] D01968 ,
D06378 ,
D06379 ,
D08689
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
91Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion, generic medicinal product.[1] Zoledronic acid[4] D01968 ,
D06378 ,
D06379 ,
D08689
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
92Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion,generic medicinal product[1] Zoledronic acid[4] D01968 ,
D06378 ,
D06379 ,
D08689
[1] FDPS 💬[4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 274
93Zometa----[1] 274
94Ácido risedrónico----[1] 274