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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Acetate[1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
2ADVATE[1] Antihemophilic factor, human recombinant[1] D02958 --[1] 288
3ADVATE (rAHF - PFM)[1] Antihemophilic factor, human recombinant[1] D02958 --[1] 288
4ADVATE (rAHF-PFM)[1] Antihemophilic factor, human recombinant[1] D02958 --[1] 288
5ADVATE 1000 IU powder and solvent for solution for injection[1] Antihemophilic factor, human recombinant[1] D02958 --[1] 288
6ADVATE 1000IU powder and solvent for solution for injection[1] Antihemophilic factor, human recombinant[1] D02958 --[1] 288
7ADVATE 500 IU powder and solvent for solution for injection[1] Antihemophilic factor, human recombinant[1] D02958 --[1] 288
8Alphanate[1] Von Willebrand factor human---[1] 288
9Alphanate 1000 I.U.[1] Von Willebrand factor human---[1] 288
10Alphanate 1500 I.U.[1] Von Willebrand factor human---[1] 288
11Alphanate SD/HT[1] Von Willebrand factor human---[1] 288
12ALPHANATE*INF 1F 1000UI+F 10ML[1] Von Willebrand factor human---[1] 288
13ALPHANATE*INF 1F 1500UI+F 10ML[1] Von Willebrand factor human---[1] 288
14ALPHANATE*INF 1F 250UI+F 5ML[1] Von Willebrand factor human---[1] 288
15ALPHANATE*INF 1F 500UI+F 5ML[1] Von Willebrand factor human---[1] 288
16Antihemophilic Factor (Recombinant)----[1] 288
17APCC, aPCC + TXA----[1] 288
18ARC 1779----[2] 64, 288
19ARC1779----[2] 64, 288
20ARC1779 Injection----[2] 64, 288
21BAX 111----[1] 288
22BAX111----[1] 288
23Biostate----[1] 288
24Biostate®----[1] 288
25BIVV001 (rFVIIIFc-VWF-XTEN)----[1] 288
26Blood coagulation Factor VIII and vWF, human[1] Beroctocog alfa---[1] 288
27Blood sample----[18] 8, 13, 46, 49, 51, 53, 61, 65, 66, 84, 96, 97, 107, 127, 235, 274, 288, 299
28BORTEZOMIB[1] Bortezomib[1] D03150 [1] PSMB5 💬[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[16] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 228, 256, 283, 288, 331
29Catridecacog[1] Catridecacog[1] D10532 --[2] 97, 288
30Chloride[1] Chloride ion---[29] 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 271, 288, 296, 297, 299, 338
31Cluvot----[1] 288
32Coagadex[1] Coagulation factor X human---[1] 288
33Coagulación factor VIII[1] Beroctocog alfa---[1] 288
34Coagulation factor VIII[1] Beroctocog alfa---[1] 288
35Coagulation factor X[1] Coagulation factor X human---[1] 288
36Coagulation factor XIII[1] Factor XIII (human)---[1] 288
37CoFactor----[3] 6, 265, 288
38Cyclophosphamide[1] Cyclophosphamide[2] D00287 ,
D07760 		--[45] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
39DDAVP[1] Desmopressin[2] D00291 ,
D02235 		[2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[2] 75, 288
40DDAVP (Desmopressin)[1] Desmopressin[2] D00291 ,
D02235 		[2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 288
41Desmopressin[1] Desmopressin[2] D00291 ,
D02235 		[2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[5] 6, 64, 72, 225, 288
42Desmopressin acetate[2] Acetate,
Desmopressin		[2] D00291 ,
D02235 		[2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[2] 64, 288
43Desmopressine[1] Desmopressin[2] D00291 ,
D02235 		[2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[2] 225, 288
44Diagnostic Test: blood sample , doppler of uterine vessel and placenta----[1] 288
45Diagnostic Test: fibrinogen plasma concentration, coagulation factor XIII activity[2] Factor XIII (human),
Fibrinogen human		---[1] 288
46Efanesoctocog alfa[1] Efanesoctocog alfa---[1] 288
47Efanesoctocog alfa (BIVV001)[1] Efanesoctocog alfa---[1] 288
48Emicizumab[1] Emicizumab[1] D10821 [2] F10,
F9 💬		[1] Complement and coagulation cascades 💬[1] 288
49Emicizumab (ACE910, RO5534262)[1] Emicizumab[1] D10821 [2] F10,
F9 💬		[1] Complement and coagulation cascades 💬[1] 288
50Emicizumab Injection[1] Emicizumab[1] D10821 [2] F10,
F9 💬		[1] Complement and coagulation cascades 💬[1] 288
51Eqwilate----[1] 288
52F13CD----[1] 288
53F8VR----[1] 288
54FACTANE 200 IU/ml----[1] 288
55Factor VIII[1] Beroctocog alfa---[1] 288
56Factor VIII concentrate[1] Beroctocog alfa---[1] 288
57Factor von Willebrand[1] Von Willebrand factor human---[1] 288
58FACTOR X[1] Coagulation factor X human---[1] 288
59Factor XIII[1] Factor XIII (human)---[3] 51, 97, 288
60Factor XIII Concentrate (Human)[1] Factor XIII (human)---[1] 288
61Factor XIII Concentrate (Human), Pasteurized[1] Factor XIII (human)---[1] 288
62Fanhdi----[1] 288
63FANHDI 100 UI----[1] 288
64Fanhdi 100 UI FVIII-120 UI FVW----[1] 288
65FANHDI 25 UI----[1] 288
66Fanhdi 25 UI FVIII-30 UI FVW----[1] 288
67FANHDI 250UI*1F 250UI+F 10ML----[1] 288
68FANHDI 50 UI----[1] 288
69Fanhdi 50 UI FVIII-60 UI FVW----[1] 288
70FANHDI*INF FL 250UI+SIR SOLV+S----[1] 288
71FANHDI*INF FL 500UI+SIR SOLV+S----[1] 288
72FANHDI*INF FL1000UI+SIR SOLV+S----[1] 288
73FANHDI*INF FL250UI+SIR SOLV+S----[1] 288
74Fibrinogen[1] Fibrinogen human---[3] 14, 65, 288
75Fibrogammin P----[1] 288
76Fibrogammin® P----[1] 288
77Fibrogammin®P----[1] 288
78FXIII Concentrate (Human)----[1] 288
79FXIII Concentrate (Human) (FXIII)----[1] 288
80Haemate P----[1] 288
81Haemate P® (Human Coagulation Factor VIII)[2] Antihemophilic factor human,
Beroctocog alfa		---[1] 288
82Haemate-P, Wilate[1] Von Willebrand factor human---[1] 288
83Haemate® P 250----[1] 288
84Hemlibra[1] Emicizumab[1] D10821 [2] F10,
F9 💬		[1] Complement and coagulation cascades 💬[1] 288
85Hemlibra®[1] Emicizumab[1] D10821 [2] F10,
F9 💬		[1] Complement and coagulation cascades 💬[1] 288
86HEMOFIX----[1] 288
87HUMAN COAGULATION FACTOR VIII[1] Antihemophilic factor human---[1] 288
88Human coagulation Factor VIII / von Willebrand Factor[2] Antihemophilic factor human,
Von Willebrand factor human		---[1] 288
89Human coagulation factor VIII associated with Von Willebrand factor (VWF)[3] Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---[1] 288
90HUMAN COAGULATION FACTOR VIII, VON WILLEBRAND FACTOR COMPLEX[2] Antihemophilic factor human,
Von Willebrand factor human		---[1] 288
91Human Coagulation FACTOR X[1] Coagulation factor X human---[1] 288
92Human factor X[1] Coagulation factor X human---[1] 288
93HUMAN VON WILLEBRAND FACTOR[1] Von Willebrand factor human---[1] 288
94Human von Willebrand factor (VWF) and coagulation factor VIII (FVIII)[2] Beroctocog alfa,
Von Willebrand factor human		---[1] 288
95Human VWF/FVIII concentrate----[1] 288
96Humate-P[1] Von Willebrand factor human---[1] 288
97IL-11[1] Oprelvekin[1] D05266 [1] IL11RA 💬[3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[1] 288
98Interleukin 11[1] Oprelvekin[1] D05266 [1] IL11RA 💬[3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[1] 288
99Interleukin-11[1] Oprelvekin[1] D05266 [1] IL11RA 💬[3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[2] 96, 288
100Marketed plasma-derived VWF/FVIII concentrate----[1] 288
101Minirin[1] Desmopressin[2] D00291 ,
D02235 		[2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[2] 64, 288
102Minrin----[1] 288
103Natriumchlorid[1] Sodium chloride[1] D02056 --[1] 288
104Natriumchlorid 0,9 %[1] Sodium chloride[1] D02056 --[1] 288
105Neumega (Oprelvekin, Interleukin 11, IL-11)[1] Oprelvekin[1] D05266 [1] IL11RA 💬[3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[1] 288
106NN 1841----[1] 288
107NN1841----[1] 288
108OBI-1----[1] 288
109OBIZUR[1] Susoctocog alfa[1] D10831 --[1] 288
110Obyoctocog alfa----[1] 288
111Octanate[1] Beroctocog alfa---[1] 288
112OCTANATE 100 UI/ml, poudre et solvant pour solution injectable[1] Beroctocog alfa---[1] 288
113OCTANATE 50 UI/ml, poudre et solvant pour solution injectable[1] Beroctocog alfa---[1] 288
114OCTOCOG ALFA[1] Antihemophilic factor, human recombinant[1] D02958 --[1] 288
115Octostim----[2] 64, 288
116Oprelvekin[1] Oprelvekin[1] D05266 [1] IL11RA 💬[3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[1] 288
117Oprelvekin, Interleukin 11, IL-11[1] Oprelvekin[1] D05266 [1] IL11RA 💬[3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[1] 288
118Optivate----[1] 288
119Optivate® (Human Coagulation Factor VIII)[2] Antihemophilic factor human,
Beroctocog alfa		---[1] 288
120Other: Use of a postpartum diary and additional blood draws----[1] 288
121Other: Use of a postpartum diary and additional blood draws.----[1] 288
122Physiologische Kochsalzlösung Fresenius - Infusionslösung----[1] 288
123Phytomenadione[1] Phylloquinone[1] D00148 --[1] 288
124Plasma-derived FVIII/VWF concentrate----[1] 288
125Prednisone[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
126Prothrombin[1] Prothrombin---[1] 288
127Prothrombin Complex Concentrate[2] Factor IX Complex (Human),
Prothrombin		---[1] 288
128RAHF[1] Antihemophilic factor, human recombinant[1] D02958 --[1] 288
129Recombinant coagulation FVIII Fc – von Willebrand factor – XTEN fusion protein[1] Von Willebrand factor human---[1] 288
130Recombinant coagulation FVIII Fc –von Willebrand factor – XTEN fusion protein[1] Von Willebrand factor human---[1] 288
131Recombinant factor VIIII (rFVIII)----[1] 288
132Recombinant Factor XIII[1] Factor XIII (human)---[1] 288
133Recombinant Factor XIII (rFXIII)[1] Factor XIII (human)---[2] 97, 288
134RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTO[1] Antihemophilic factor human---[1] 288
135RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR -[3] Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---[1] 288
136RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR - XTEN FUSION PROTEIN[2] Antihemophilic factor human,
Von Willebrand factor human		---[1] 288
137RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR -XTEN FUSION PROTEIN[3] Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---[1] 288
138Recombinant human von Willebrand Factor[1] Vonicog alfa[1] D08681 --[1] 288
139Recombinant interleukin-11[1] Oprelvekin[1] D05266 [1] IL11RA 💬[3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[1] 288
140Recombinant porcine coagulation factor VIII (B domain deleted)[1] Beroctocog alfa---[1] 288
141Recombinant porcine coagulation factor VIII (B-domain deleted)[1] Beroctocog alfa---[1] 288
142Recombinant Von Willebrand factor[1] Von Willebrand factor human---[1] 288
143Recombinant von Willebrand Factor (rVWF)[1] Von Willebrand factor human---[1] 288
144Recombinant von Willebrand Factor 1300IU[1] Vonicog alfa[1] D08681 --[1] 288
145Recombinant von Willebrand Factor 650IU[1] Vonicog alfa[1] D08681 --[1] 288
146Recombinant von Willebrand factor : recombinant FVIII (rVWF:rFVIII)[1] Von Willebrand factor human---[1] 288
147Recomibnant human Von Willebrand Factor[1] Vonicog alfa[1] D08681 --[1] 288
148RFVIIa[1] Coagulation factor VIIa Recombinant Human[1] D00172 --[1] 288
149RFVIIa, rFVIIa + TXA[1] Coagulation factor VIIa Recombinant Human[1] D00172 --[1] 288
150RFVIII----[1] 288
151Rituxan[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[4] 46, 60, 256, 288
152Rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[49] 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
153RO5534262 EMICIZUMAB[1] Emicizumab[1] D10821 [2] F10,
F9 💬		[1] Complement and coagulation cascades 💬[1] 288
154Rurioctocog alfa pegol[1] Rurioctocog alfa pegol[1] D10760 --[1] 288
155RVWF----[1] 288
156Saline solution----[4] 2, 34, 288, 299
157Simvastatin[1] Simvastatin[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
158Simvastatine[1] Simvastatin[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 6, 13, 288
159Sodium chloride[2] Chloride ion,
Sodium chloride		[1] D02056 --[21] 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 168, 193, 227, 228, 271, 288, 299
160SODIUM CHLORIDE SOLUTION 0.9%[2] Chloride ion,
Sodium chloride		[1] D02056 --[3] 60, 288, 299
161Standard of Care for Haemophilia A----[1] 288
162Standard of Care FVIII Replacement therapy----[1] 288
163Steroid----[1] 288
164Sublingual videomicroscopy----[1] 288
165TAK-672----[1] 288
166Tranexamic acid[1] Tranexamic acid[1] D01136 [1] PLG 💬[4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬[6] 46, 70, 215, 227, 288, 299
167Tranexamic Acid Injection [Cyklokapron][1] Tranexamic acid[1] D01136 [1] PLG 💬[4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬[1] 288
168Uterine----[3] 118, 280, 288
169Vessel----[4] 13, 51, 271, 288
170VEYONDI 650IU powder and solvent for solution for injection----[1] 288
171Veyvondi[1] Vonicog alfa[1] D08681 --[1] 288
172VEYVONDI 1300I IU powder and solvent for solution for injection[1] Vonicog alfa[1] D08681 --[1] 288
173VEYVONDI 1300IU powder and solvent for solution for injection[1] Vonicog alfa[1] D08681 --[1] 288
174VEYVONDI 650IU powder and solvent for solution for injection[1] Vonicog alfa[1] D08681 --[1] 288
175Von willebrand factor[1] Von Willebrand factor human---[2] 64, 288
176Von Willebrand factor (Recombinant)[1] Von Willebrand factor human---[1] 288
177Von Willebrand factor and coagulation factor VIII in combination[2] Beroctocog alfa,
Von Willebrand factor human		---[1] 288
178Von Willebrand Factor Antigen[1] Von Willebrand factor human---[1] 288
179Von Willebrand Factor Ristocetin Cofactor[1] Von Willebrand factor human---[1] 288
180Von Willebrand Faktor----[1] 288
181Voncento[1] Von Willebrand factor human---[1] 288
182Voncento, Biostate®[1] Von Willebrand factor human---[1] 288
183Voncento®[1] Von Willebrand factor human---[1] 288
184VONICOG ALFA[1] Vonicog alfa[1] D08681 --[1] 288
185VWD factor VIII concentrate[1] Beroctocog alfa---[1] 288
186VWF replacement therapy with Wilate[1] Von Willebrand factor human---[1] 288
187VWF SD-35-DH----[1] 288
188VWF-containing products----[1] 288
189VWF/FVIII products----[1] 288
190WILATE[1] Von Willebrand factor human---[1] 288
191Wilate 1000[1] Von Willebrand factor human---[1] 288
192WILATE 1000 I.U.[1] Von Willebrand factor human---[1] 288
193WILATE 450[1] Von Willebrand factor human---[1] 288
194Wilate 500[1] Von Willebrand factor human---[1] 288
195WILATE 500 I.U.[1] Von Willebrand factor human---[1] 288
196WILATE 900[1] Von Willebrand factor human---[1] 288
197WILATE® 450[1] Von Willebrand factor human---[1] 288
198WILFACTIN----[1] 288
199Willfact----[1] 288
200Wiloctin----[1] 288