1 | (R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE | [1] Pyrazole Pyrazole | - | - | - | [1] 58 58 |
2 | (R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1METHYL-1H-PYRAZOLE-4-CARBOXAMIDE | [1] Pyrazole Pyrazole | - | - | - | [1] 58 58 |
3 | (R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1METHYL-1HPYRAZOLE-4-CARBOXAMIDE | - | - | - | - | [1] 58 58 |
4 | 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride | [1] Piperazine Piperazine | [6] D00807
D00807
,
D01393
,
D02127
,
D02145
,
D05486
,
D06224
| - | - | [1] 58 58 |
5 | 3D electrocardiographic mapping (ECM) | - | - | - | - | [1] 58 58 |
6 | Acetylcysteine | [1] Acetylcysteine Acetylcysteine | [1] D00221
D00221
| - | - | [20] 6 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 |
7 | Adenosine | [1] Adenosine Adenosine | [1] D00045
D00045
| [4] ADORA1 ADORA1, ADORA2A, ADORA2B, ADORA3 💬 | [12] Alcoholism Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [3] 13 13, 58, 65 |
8 | Air | - | - | - | - | [8] 3 3, 13, 51, 58, 85, 97, 193, 299 |
9 | Alcohol | [1] Ethanol Ethanol | [4] D00068
D00068
,
D02798
,
D04855
,
D06542
| - | - | [4] 13 13, 58, 279, 298 |
10 | Alcohol Septal Ablation | [1] Ethanol Ethanol | [4] D00068
D00068
,
D02798
,
D04855
,
D06542
| - | - | [1] 58 58 |
11 | Amyl Nitrite | [2] Amyl Nitrite Amyl Nitrite, Nitrite | [1] D00517
D00517
| [3] GUCY1A1 GUCY1A1, GUCY1A2, GUCY1B1 💬 | [11] Circadian entrainment Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
12 | Amyl nitrite inhalation | [2] Amyl Nitrite Amyl Nitrite, Nitrite | [1] D00517
D00517
| [3] GUCY1A1 GUCY1A1, GUCY1A2, GUCY1B1 💬 | [11] Circadian entrainment Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
13 | Antiarrhythmic drugs | - | - | - | - | [1] 58 58 |
14 | Arginina | [1] Arginine Arginine | [1] D02982
D02982
| - | - | [2] 58 58, 78 |
15 | Arginine | [1] Arginine Arginine | [1] D02982
D02982
| - | - | [11] 46 46, 58, 67, 78, 96, 97, 98, 113, 210, 251, 299 |
16 | Aspirin | [1] Acetylsalicylic acid Acetylsalicylic acid | [1] D00109
D00109
| [2] PTGS1 PTGS1, PTGS2 💬 | [23] Alzheimer disease Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬 | [12] 13 13, 22, 34, 46, 49, 51, 58, 86, 113, 158, 210, 231 |
17 | Atorvastatin | [1] Atorvastatin Atorvastatin | [3] D00258
D00258
,
D00887
,
D07474
| [1] HMGCR HMGCR 💬 | [4] AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | [18] 13 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 |
18 | B-lines SE | - | - | - | - | [3] 58 58, 86, 215 |
19 | Behavioral: Lifestyle | - | - | - | - | [1] 58 58 |
20 | Bluefish | [1] Bluefish Bluefish | - | - | - | [1] 58 58 |
21 | BNP | - | - | - | - | [2] 46 46, 58 |
22 | BNP blood sample test | - | - | - | - | [1] 58 58 |
23 | C01EB18 | - | - | - | - | [1] 58 58 |
24 | Candesartan | [1] Candesartan Candesartan | [1] D00522
D00522
| [1] AGTR1 AGTR1 💬 | [16] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [2] 58 58, 67 |
25 | Carnitine | [1] Levocarnitine Levocarnitine | [3] D02030
D02030
,
D02176
,
D04713
| - | - | [9] 5 5, 13, 58, 86, 96, 97, 265, 298, 316 |
26 | CAS Name: 1,4-Benzoxazepin-5(2H)-one, 3,4-dihydro-4-(2-pyrimidinylmethyl)-7-[4- (trifluoromethoxy)phenyl] IUPAC Name: 4-(Pyrimidin-2-ylmethyl)-7-[4- (trifluoromethoxy)phenyl]-3,4-dihydro-1,4-benzoxazepin-5(2H)-one | - | - | - | - | [1] 58 58 |
27 | CAS Name: 1,4-Benzoxazepin-5(2H)-one, 3,4-dihydro-4-(2-pyrimidinylmethyl)-7-[4-(trifluoromethoxy)phenyl] IUPAC Name: 4-(Pyrimidin-2-ylmethyl)-7-[4-(trifluoromethoxy)phenyl]-3,4-dihydro-1,4-benzoxazepin-5(2H)-one | - | - | - | - | [1] 58 58 |
28 | Cibenzoline | [1] Cibenzoline Cibenzoline | [1] D03492
D03492
| [5] SCN1A SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 | [3] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬 | [1] 58 58 |
29 | CK-3773274 | - | - | - | - | [1] 58 58 |
30 | CK-3773274 (10 - 30 mg) | - | - | - | - | [1] 58 58 |
31 | CK-3773274 (5 - 15 mg) | - | - | - | - | [1] 58 58 |
32 | CK-3773274 (5 - 20 mg) | - | - | - | - | [1] 58 58 |
33 | CK-3773274 (5 mg, 10 mg, 15 mg and 20 mg) | - | - | - | - | [1] 58 58 |
34 | CK-3773274 - Granules in Capsule | - | - | - | - | [1] 58 58 |
35 | CK-3773274 - Tablets | - | - | - | - | [1] 58 58 |
36 | Coronary flow reserve SE | - | - | - | - | [3] 58 58, 86, 215 |
37 | CT-G20 | - | - | - | - | [1] 58 58 |
38 | Cufence | [1] Triethylenetetramine Triethylenetetramine | - | - | - | [2] 58 58, 171 |
39 | Cyclosporine | [1] Cyclosporine Cyclosporine | [1] D00184
D00184
| [5] PPP3CA PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | [33] Alzheimer disease Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬 | [37] 11 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 |
40 | Cyclosporine A | [1] Cyclosporine Cyclosporine | [1] D00184
D00184
| [5] PPP3CA PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 | [33] Alzheimer disease Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬 | [11] 19 19, 20, 36, 49, 50, 53, 58, 60, 107, 234, 283 |
41 | Diagnostic Test: Air venous plethysmography | - | - | - | - | [1] 58 58 |
42 | Diagnostic Test: Echocardiography | - | - | - | - | [1] 58 58 |
43 | Diagnostic Test: Electrocardiogram | - | - | - | - | [1] 58 58 |
44 | Diagnostic Test: Exercise Stress Transthoracic Echocardiogram | - | - | - | - | [1] 58 58 |
45 | Diagnostic Test: Holter ECG | - | - | - | - | [1] 58 58 |
46 | Diagnostic Test: Phosphorous Magnetic Resonance Spectroscopy | [1] Phosphorus Phosphorus | - | - | - | [1] 58 58 |
47 | Diagnostic Test: Upper member arterial Doppler echography with analysis of FMD | - | - | - | - | [1] 58 58 |
48 | Diastolic function SE | - | - | - | - | [3] 58 58, 86, 215 |
49 | Diltiazem | [1] Diltiazem Diltiazem | [3] D00616
D00616
,
D03830
,
D07845
| [4] CACNA1C CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 | [37] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [3] 51 51, 58, 86 |
50 | Diovan | [1] Valsartan Valsartan | [1] D00400
D00400
| [1] AGTR1 AGTR1 💬 | [16] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
51 | Diovan 160 mg | [1] Valsartan Valsartan | [1] D00400
D00400
| [1] AGTR1 AGTR1 💬 | [16] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
52 | Diovan 40 mg | [1] Valsartan Valsartan | [1] D00400
D00400
| [1] AGTR1 AGTR1 💬 | [16] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
53 | Diovan 80 mg | [1] Valsartan Valsartan | [1] D00400
D00400
| [1] AGTR1 AGTR1 💬 | [16] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
54 | Dobutamine | [1] Dobutamine Dobutamine | [4] D00632
D00632
,
D03879
,
D03880
,
D03881
| [1] ADRB1 ADRB1 💬 | [11] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [3] 57 57, 58, 215 |
55 | Echo and myocardial contrast echocardiography perfusion imaging | - | - | - | - | [1] 58 58 |
56 | Echocardiography (TEE) | - | - | - | - | [1] 58 58 |
57 | Eleclazine | [1] Eleclazine Eleclazine | [1] D11155
D11155
| [5] SCN1A SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬 | [3] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬 | [1] 58 58 |
58 | Endothelial function biomarkers | - | - | - | - | [1] 58 58 |
59 | Entresto | [1] Valsartan Valsartan | [1] D00400
D00400
| [1] AGTR1 AGTR1 💬 | [16] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
60 | Esmolol | [1] Esmolol Esmolol | [2] D00644
D00644
,
D07916
| [1] ADRB1 ADRB1 💬 | [11] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
61 | Gadolinium | [1] Gadolinium Gadolinium | - | - | - | [6] 13 13, 34, 46, 58, 65, 86 |
62 | Gold | [1] Gold Gold | - | - | - | [43] 2 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318 |
63 | Gradient | - | - | - | - | [4] 58 58, 86, 149, 215 |
64 | GS-6615 3 mg | - | - | - | - | [1] 58 58 |
65 | GS-6615 3 mg Pink | - | - | - | - | [1] 58 58 |
66 | GS-6615 3 mg White | - | - | - | - | [1] 58 58 |
67 | GS-6615 6 mg | - | - | - | - | [1] 58 58 |
68 | GS-6615 6 mg White | - | - | - | - | [1] 58 58 |
69 | Gutron 2,5mg | - | - | - | - | [1] 58 58 |
70 | Gutron 5mg | - | - | - | - | [1] 58 58 |
71 | Hyperpolarized 13C-Pyruvate | - | - | - | - | [1] 58 58 |
72 | IMB-1018972 | - | - | - | - | [1] 58 58 |
73 | Imukin | - | - | - | - | [3] 18 18, 58, 228 |
74 | IMUKIN - 6 FLACONI 0.5 ML 100 MCG | - | - | - | - | [2] 18 18, 58 |
75 | Insertable cardiac monitor | [1] Methamidophos Methamidophos | - | - | - | [1] 58 58 |
76 | LCZ696 | - | - | - | - | [1] 58 58 |
77 | LCZ696 100 mg | - | - | - | - | [1] 58 58 |
78 | LCZ696 200 mg | - | - | - | - | [1] 58 58 |
79 | LCZ696 50 mg | - | - | - | - | [1] 58 58 |
80 | Left ventricular contractile reserve SE | - | - | - | - | [3] 58 58, 86, 215 |
81 | Left ventricular outflow tract gradient SE | - | - | - | - | [3] 58 58, 86, 215 |
82 | Losartan | [1] Losartan Losartan | [2] D00357
D00357
,
D08146
| [1] AGTR1 AGTR1 💬 | [16] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [18] 17 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
83 | Losartan Bluefish 50 mg | [2] Bluefish Bluefish, Losartan | [2] D00357
D00357
,
D08146
| [1] AGTR1 AGTR1 💬 | [16] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
84 | Magnetic resonance imaging (MRI) with gadolinium enhancement | [1] Gadolinium Gadolinium | - | - | - | [1] 58 58 |
85 | Magnetic resonance imaging (MRI) without gadolinium enhancement | [1] Gadolinium Gadolinium | - | - | - | [1] 58 58 |
86 | Mangafodipir | [1] Mangafodipir Mangafodipir | [1] D08262
D08262
| - | - | [2] 13 13, 58 |
87 | MAVACAMTEN | [1] Mavacamten Mavacamten | [1] D12265
D12265
| [1] MYH7 MYH7 💬 | [7] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Thyroid hormone signaling pathway, Viral myocarditis, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
88 | MEK162 | - | - | - | - | [2] 58 58, 195 |
89 | Metoprolol | [1] Metoprolol Metoprolol | [3] D00601
D00601
,
D02358
,
D05011
| [1] ADRB1 ADRB1 💬 | [11] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [6] 17 17, 57, 58, 113, 193, 226 |
90 | Metoprolol succinate | [1] Metoprolol Metoprolol | [3] D00601
D00601
,
D02358
,
D05011
| [1] ADRB1 ADRB1 💬 | [11] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [4] 57 57, 58, 113, 193 |
91 | Metoprololsuccinat | - | - | - | - | [1] 58 58 |
92 | Midodrine | [1] Midodrine Midodrine | [2] D01307
D01307
,
D08220
| [3] ADRA1A ADRA1A, ADRA1B, ADRA1D 💬 | [7] AMPK signaling pathway AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [3] 6 6, 17, 58 |
93 | MIDODRINE HYDROCHLORIDE | [1] Midodrine Midodrine | [2] D01307
D01307
,
D08220
| [3] ADRA1A ADRA1A, ADRA1B, ADRA1D 💬 | [7] AMPK signaling pathway AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
94 | Mitral regurgitation SE | - | - | - | - | [3] 58 58, 86, 215 |
95 | MONITOR | [1] Methamidophos Methamidophos | - | - | - | [20] 2 2, 11, 13, 19, 28, 46, 49, 58, 65, 70, 81, 85, 86, 98, 113, 118, 129, 298, 299, 300 |
96 | MYK-461 | - | - | - | - | [1] 58 58 |
97 | N-Acetylcysteine | [1] Acetylcysteine Acetylcysteine | [1] D00221
D00221
| - | - | [11] 6 6, 13, 19, 20, 49, 58, 85, 111, 164, 299, 337 |
98 | Nitrate | [1] Nitrate Nitrate | [1] D02313
D02313
| - | - | [3] 58 58, 113, 299 |
99 | Nitrite | [1] Nitrite Nitrite | - | - | - | [3] 58 58, 86, 299 |
100 | NO | - | - | - | - | [12] 6 6, 13, 46, 58, 62, 86, 96, 97, 222, 226, 299, 321 |
101 | Other: Exercise echocardiography | - | - | - | - | [1] 58 58 |
102 | Other: Mangafodipir trisodium | [1] Mangafodipir Mangafodipir | [1] D08262
D08262
| - | - | [1] 58 58 |
103 | Other: Squat-to-stand maneuver | - | - | - | - | [1] 58 58 |
104 | Other: Valsalva | - | - | - | - | [1] 58 58 |
105 | Other: Walk distance test | - | - | - | - | [1] 58 58 |
106 | Perhexiline | [1] Perhexiline Perhexiline | [2] D05442
D05442
,
D08340
| [8] CACNA1C CACNA1C, CACNA1D, CACNA1F, CACNA1S, CPT1A, CPT1B, CPT1C, CPT2 💬 | [47] AMPK signaling pathway AMPK signaling pathway, Adipocytokine signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Dopaminergic synapse, Fatty acid degradation, Fatty acid metabolism, GABAergic synapse, Glucagon signaling pathway, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin resistance, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, PPAR signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Thermogenesis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [2] 58 58, 272 |
107 | Perindopril | [1] Perindopril Perindopril | [2] D00624
D00624
,
D03753
| [1] ACE ACE 💬 | [6] Chagas disease Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬 | [4] 58 58, 113, 167, 222 |
108 | PERINDOPRIL ARGININA | [2] Arginine Arginine, Perindopril | [3] D00624
D00624
,
D02982
,
D03753
| [1] ACE ACE 💬 | [6] Chagas disease Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬 | [1] 58 58 |
109 | Perindopril arginine | [2] Arginine Arginine, Perindopril | [3] D00624
D00624
,
D02982
,
D03753
| [1] ACE ACE 💬 | [6] Chagas disease Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬 | [1] 58 58 |
110 | Perxexiline | - | - | - | - | [1] 58 58 |
111 | Pexsig | - | - | - | - | [1] 58 58 |
112 | Phosphorous | [1] Phosphorus Phosphorus | - | - | - | [1] 58 58 |
113 | Piperazine | [1] Piperazine Piperazine | [6] D00807
D00807
,
D01393
,
D02127
,
D02145
,
D05486
,
D06224
| - | - | [2] 58 58, 272 |
114 | Pirfenidone | [1] Pirfenidone Pirfenidone | [1] D01583
D01583
| [6] CCL2 CCL2, IL10, IL1A, IL1B, IL6, TNF 💬 | [84] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [11] 13 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
115 | Post-CPB Drug: Dobutamine Hydrochloride | [1] Dobutamine Dobutamine | [4] D00632
D00632
,
D03879
,
D03880
,
D03881
| [1] ADRB1 ADRB1 💬 | [11] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
116 | Pre and post-CPB Drug: Dobutamine Hydrochloride | [1] Dobutamine Dobutamine | [4] D00632
D00632
,
D03879
,
D03880
,
D03881
| [1] ADRB1 ADRB1 💬 | [11] Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
117 | Procaptan | - | - | - | - | [1] 58 58 |
118 | PROCAPTAN - 10 MG COMPRESSE RIVESTITE CON FILM 60 COMPRESSE IN CONTENITORE PER COMPRESSE PP | - | - | - | - | [1] 58 58 |
119 | PROCAPTAN - 5 MG COMPRESSE RIVESTITE CON FILM 10 COMPRESSE IN CONTENITORE PER COMPRESSE PP | - | - | - | - | [1] 58 58 |
120 | Pulmonary hemodynamics SE | - | - | - | - | [3] 58 58, 86, 215 |
121 | Pyrazole | [1] Pyrazole Pyrazole | - | - | - | [1] 58 58 |
122 | RANEXA | [1] Ranolazine Ranolazine | [2] D05700
D05700
,
D05701
| - | - | [1] 58 58 |
123 | RANEXA - 750 MG - COMPRESSA A RILASCIO PROLUNGATO- USO ORALE - BLISTER (PVC/PVDC/ALLUMINIO) 60 COMPRESSE | [1] Ranolazine Ranolazine | [2] D05700
D05700
,
D05701
| - | - | [1] 58 58 |
124 | RANEXA*60CPR 500MG R.P. | [1] Ranolazine Ranolazine | [2] D05700
D05700
,
D05701
| - | - | [1] 58 58 |
125 | RANEXA*60CPR 750MG R.P. | [1] Ranolazine Ranolazine | [2] D05700
D05700
,
D05701
| - | - | [1] 58 58 |
126 | Ranolazina | [1] Ranolazine Ranolazine | [2] D05700
D05700
,
D05701
| - | - | [1] 58 58 |
127 | Ranolazina Ranexa | [1] Ranolazine Ranolazine | [2] D05700
D05700
,
D05701
| - | - | [1] 58 58 |
128 | Ranolazine | [1] Ranolazine Ranolazine | [2] D05700
D05700
,
D05701
| - | - | [6] 2 2, 58, 86, 96, 113, 114 |
129 | Ranolazine 1000 mg PR tablets | [1] Ranolazine Ranolazine | [2] D05700
D05700
,
D05701
| - | - | [1] 58 58 |
130 | Ranolazine 500 mg PR tablets | [1] Ranolazine Ranolazine | [2] D05700
D05700
,
D05701
| - | - | [1] 58 58 |
131 | Ranolazine 750 mg PR tablets | [1] Ranolazine Ranolazine | [2] D05700
D05700
,
D05701
| - | - | [1] 58 58 |
132 | Ranolazine PR (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die | [1] Ranolazine Ranolazine | [2] D05700
D05700
,
D05701
| - | - | [1] 58 58 |
133 | RAS | - | - | - | - | [4] 6 6, 13, 58, 66 |
134 | Regadenoson | [1] Regadenoson Regadenoson | [1] D05711
D05711
| [1] ADORA2A ADORA2A 💬 | [7] Alcoholism Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬 | [1] 58 58 |
135 | RF catheter ablation | - | - | - | - | [1] 58 58 |
136 | Sacubitril | [1] Sacubitril Sacubitril | [1] D10225
D10225
| [1] MME MME 💬 | [4] Alzheimer disease Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬 | [1] 58 58 |
137 | SACUBITRIL VALSARTAN | [2] Sacubitril Sacubitril, Valsartan | [2] D00400
D00400
,
D10225
| [2] AGTR1 AGTR1, MME 💬 | [19] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hematopoietic cell lineage, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Protein digestion and absorption, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
138 | Sacubitril/Valsartan | [2] Sacubitril Sacubitril, Valsartan | [2] D00400
D00400
,
D10225
| [2] AGTR1 AGTR1, MME 💬 | [19] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hematopoietic cell lineage, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Protein digestion and absorption, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
139 | Sodium Nitrate | [2] Nitrate Nitrate, Sodium nitrate | [1] D02313
D02313
| - | - | [2] 58 58, 113 |
140 | Spironolactone | [1] Spironolactone Spironolactone | [1] D00443
D00443
| [1] NR3C2 NR3C2 💬 | [1] Aldosterone-regulated sodium reabsorption Aldosterone-regulated sodium reabsorption 💬 | [7] 58 58, 67, 86, 113, 210, 218, 225 |
141 | Surgical Septal Myectomy | - | - | - | - | [1] 58 58 |
142 | Trans-right ventricular alcohol septal ablation (TRVASA) | [1] Ethanol Ethanol | [4] D00068
D00068
,
D02798
,
D04855
,
D06542
| - | - | [1] 58 58 |
143 | Treatment BX1514M | - | - | - | - | [1] 58 58 |
144 | Trientine | [1] Triethylenetetramine Triethylenetetramine | - | - | - | [2] 58 58, 171 |
145 | Trientine Dihydrochloride | [1] Triethylenetetramine Triethylenetetramine | - | - | - | [2] 58 58, 171 |
146 | Triethylinetetramine dihydrochloride | - | - | - | - | [1] 58 58 |
147 | Trimetazidine | [1] Trimetazidine Trimetazidine | [1] D08642
D08642
| - | - | [3] 2 2, 58, 86 |
148 | Trimetazidine Dihydrochloride | [1] Trimetazidine Trimetazidine | [1] D08642
D08642
| - | - | [2] 2 2, 58 |
149 | Trimetazidine Dihydrochloride 20mg | [1] Trimetazidine Trimetazidine | [1] D08642
D08642
| - | - | [1] 58 58 |
150 | TY-0305 | - | - | - | - | [1] 58 58 |
151 | Use of bioanalytical assay to monitor plasma levels of perhexiline | [2] Methamidophos Methamidophos, Perhexiline | [2] D05442
D05442
,
D08340
| [8] CACNA1C CACNA1C, CACNA1D, CACNA1F, CACNA1S, CPT1A, CPT1B, CPT1C, CPT2 💬 | [47] AMPK signaling pathway AMPK signaling pathway, Adipocytokine signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Dopaminergic synapse, Fatty acid degradation, Fatty acid metabolism, GABAergic synapse, Glucagon signaling pathway, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin resistance, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, PPAR signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Thermogenesis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [1] 58 58 |
152 | Valsartan | [1] Valsartan Valsartan | [1] D00400
D00400
| [1] AGTR1 AGTR1 💬 | [16] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [7] 57 57, 58, 66, 75, 218, 222, 224 |
153 | Vastarel | - | - | - | - | [2] 2 2, 58 |
154 | Vastarel 20mg film coated tablets | - | - | - | - | [1] 58 58 |