Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-{[4’-----[1] 79
21,2-Dihexadecanoyl-sn-Glycero-3-Phospho-(1-raac-glycerol)[1] Glycerin[1] D00028 --[1] 79
3AAV directed hLDLR gene therapy----[1] 79
4AAV8.TBG.hLDLR----[1] 79
5Acetate[1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
6AEGR-733----[1] 79
7AK102----[1] 79
8AKCEA-ANGPTL3-LRX----[2] 79, 265
9ALIROCUMAB[1] Alirocumab[1] D10335 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
10Alirocumab SAR236553 (REGN727)[1] Alirocumab[1] D10335 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
11ALN-60212----[1] 79
12ALN-PCSSC[1] Inclisiran[1] D11931 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
13AMG 145----[1] 79
14AMG145----[1] 79
15ANACETRAPIB[1] Anacetrapib[1] D08855 [1] CETP 💬[1] Cholesterol metabolism 💬[1] 79
16Atorvastatin[1] Atorvastatin[3] D00258 ,
D00887 ,
D07474 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
17Calcium[1] Calcium---[30] 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
18Calcium rosuvastatin[2] Calcium,
Rosuvastatin		[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 79
19CER-001----[1] 79
20Cholestyramine[1] Cholestyramine---[2] 13, 79
21Comparator: ezetimibe[1] Ezetimibe[1] D01966 [1] NPC1L1 💬[1] Fat digestion and absorption 💬[2] 79, 260
22Crestor[1] Rosuvastatin[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 49, 79, 299
23Crestor Film-Coated Tablet[1] Rosuvastatin[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 79
24Crestor Tablets (calcium rosuvastatin) Film-Coated tablets[2] Calcium,
Rosuvastatin		[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 79
25Current lipid-lowering treatment----[1] 79
26Dextran[1] Dextran[1] D00060 --[5] 2, 62, 79, 96, 97
27Dextran sulfate adsorption[2] Dextran,
Sulfate ion		[1] D00060 --[1] 79
28DPPG----[1] 79
29EVINACUMAB[1] Evinacumab[1] D11753 [1] ANGPTL3 💬[1] Cholesterol metabolism 💬[1] 79
30Evinacumab (REGN1500)[1] Evinacumab[1] D11753 [1] ANGPTL3 💬[1] Cholesterol metabolism 💬[1] 79
31EVOLOCUMAB[1] Evolocumab[1] D10557 [1] PCSK9 💬[1] Cholesterol metabolism 💬[2] 79, 222
32Evolocumab (AMG 145)[1] Evolocumab[1] D10557 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
33Ezetimibe[1] Ezetimibe[1] D01966 [1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260
34Fenofibrate[1] Fenofibrate[1] D00565 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[5] 8, 79, 93, 94, 265
35Fluvastatin[1] Fluvastatin[2] D00892 ,
D07983 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 79, 218, 222
36Gemcabene[1] Gemcabene---[2] 79, 265
37Glycerol[1] Glycerin[1] D00028 --[5] 6, 13, 79, 316, 317
38Heparin[1] Heparin[1] D07510 [1] SERPINC1 💬[1] Complement and coagulation cascades 💬[12] 47, 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317
39Heparin-induced extracorporeal LDL precipitation[1] Heparin[1] D07510 [1] SERPINC1 💬[1] Complement and coagulation cascades 💬[1] 79
40IBI306----[1] 79
41Implitapide[1] Implitapide---[1] 79
42Inclisiran[1] Inclisiran[1] D11931 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
43Inclisiran for injection[1] Inclisiran[1] D11931 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
44Inclisiran Sodium[1] Inclisiran[1] D11931 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
45ISIS 301012----[1] 79
46ISIS 301012 phosphorothioate oligonucleotide----[1] 79
47ISIS 703802----[1] 79
48JS002----[1] 79
49KJX839----[1] 79
50Lapaquistat[1] Lapaquistat---[1] 79
51Lapaquistat acetate and current lipid-lowering treatment[2] Acetate,
Lapaquistat		---[1] 79
52Lerodalcibep----[1] 79
53LIB003----[1] 79
54Lojuxta[1] Lomitapide[1] D09637 [1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79
55Lojuxta 10 mg hard capsules[1] Lomitapide[1] D09637 [1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79
56Lojuxta 20 mg hard capsules[1] Lomitapide[1] D09637 [1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79
57Lojuxta 5 mg hard capsules[1] Lomitapide[1] D09637 [1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79
58LOMITAPIDE[1] Lomitapide[1] D09637 [1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79
59Lomitapide 2mg hard capsules[1] Lomitapide[1] D09637 [1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79
60Lovastatin[1] Lovastatin[1] D00359 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
61MBX-8025----[3] 79, 93, 94
62MBX-8025 50 mg (Dose Escalation Period 1)----[1] 79
63MBX-8025 50 mg or 100 mg (Dose Escalation Period 2)----[1] 79
64MBX-8025 50 mg, 100 mg or 200 mg (Dose Escalation Period 3)----[1] 79
65Mipomersen[1] Mipomersen---[1] 79
66MK-0859----[1] 79
67Nicotinic acid[1] Niacin[1] D00049 --[1] 79
68Omega-3[1] Omega-3 fatty acids---[7] 13, 46, 49, 66, 79, 96, 299
69Omega-3 fatty acids[1] Omega-3 fatty acids---[2] 13, 79
70Phospholipids[1] Omega-3 fatty acids---[1] 79
71Placebo----[27] 3, 5, 6, 13, 14, 37, 40, 46, 49, 50, 51, 53, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276
72Praluent[1] Alirocumab[1] D10335 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
73Pravastatin[1] Pravastatin[2] D00893 ,
D08410 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
74PRD7255830----[1] 79
75PRD7255977----[1] 79
76PRD7256003----[1] 79
77Prednisone[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
78R727----[1] 79
79Recombinant Human Apolipoprotein----[1] 79
80Recombinant Human Apolipoprotein A-I----[1] 79
81Recombinant Human Apolipoprotein A-I/Phospholipids Complex[1] Omega-3 fatty acids---[1] 79
82Recombinant human apolipoprotein a1----[1] 79
83REGN1500----[1] 79
84REGN1500 250 mg SC/15 mg/kg IV/450 mg SC----[1] 79
85REGN7272----[1] 79
86Repatha[1] Evolocumab[1] D10557 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
87Repatha (evolocumab)[1] Evolocumab[1] D10557 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
88Repatha 140 mg Solution for Injection in Pre-filled Pen[1] Evolocumab[1] D10557 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
89Repatha 140 mg soluzione per iniezione in penna preriempita.[1] Evolocumab[1] D10557 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
90Repatha 420 mg solution for injection in cartridge[1] Evolocumab[1] D10557 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
91Repatha 420 mg soluzione per iniezione in cartuccia[1] Evolocumab[1] D10557 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
92Rosuvastatin[1] Rosuvastatin[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
93Rosuvastatin 20mg[1] Rosuvastatin[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[1] 79
94ROSUVASTATIN CALCIUM[2] Calcium,
Rosuvastatin		[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[4] 49, 79, 97, 299
95SAR236553----[1] 79
96Sfingomielina----[1] 79
97SHR-1209----[1] 79
98Simvastatin[1] Simvastatin[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
99Single intravenous (IV) dose of human Low Density Lipoprotein Receptor (LDLR) Gene Therapy----[1] 79
100Sphingomyelin----[1] 79
101Standard of Care----[10] 6, 13, 46, 49, 51, 63, 64, 79, 171, 271
102Statins----[2] 46, 79
103Sulfate[1] Sulfate ion---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 218, 222, 226, 265, 296, 297, 299
104TAK-475[1] TAK-475---[1] 79
105ZD4522----[1] 79