Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetate [1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
2 Alirocumab [2] ALIROCUMAB; Praluent[1] D10335 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
3 Anacetrapib [1] ANACETRAPIB[1] D08855 [1] CETP 💬[1] Cholesterol metabolism 💬[1] 79
4 Atorvastatin [3] Atorvastatin; Atorvastatin Calcium; Lipitor[3] D00258 ,
D00887 ,
D07474 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
5 Calcium [2] Calcio; Calcium---[30] 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
6 Cholestyramine [3] Cholestyramine; COLESTYRAMINE; Questran---[3] 13, 79, 254
7 Dextran [1] Dextran[1] D00060 --[5] 2, 62, 79, 96, 97
8 Evinacumab [1] EVINACUMAB[1] D11753 [1] ANGPTL3 💬[1] Cholesterol metabolism 💬[1] 79
9 Evolocumab [2] EVOLOCUMAB; Repatha[1] D10557 [1] PCSK9 💬[1] Cholesterol metabolism 💬[2] 79, 222
10 Ezetimibe [2] Ezetimibe; Ezetrol[1] D01966 [1] NPC1L1 💬[1] Fat digestion and absorption 💬[4] 49, 79, 93, 260
11 Fenofibrate [1] Fenofibrate[1] D00565 [1] PPARA 💬[10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[5] 8, 79, 93, 94, 265
12 Fluvastatin [1] Fluvastatin[2] D00892 ,
D07983 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[3] 79, 218, 222
13 Gemcabene [1] Gemcabene---[2] 79, 265
14 Glycerin [3] Bee venom; Glycerine; Glycerol[1] D00028 --[6] 6, 13, 79, 265, 316, 317
15 Heparin [2] Heparin; Heparin Sodium[1] D07510 [1] SERPINC1 💬[1] Complement and coagulation cascades 💬[12] 47, 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317
16 Implitapide [1] Implitapide---[1] 79
17 Inclisiran [2] ALN-PCSSC; Inclisiran[1] D11931 [1] PCSK9 💬[1] Cholesterol metabolism 💬[1] 79
18 Lapaquistat [1] Lapaquistat---[1] 79
19 Lomitapide [2] Lojuxta; LOMITAPIDE[1] D09637 [1] MTTP 💬[1] Fat digestion and absorption 💬[1] 79
20 Lovastatin [1] LOVASTATIN[1] D00359 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310
21 Mipomersen [1] Mipomersen---[1] 79
22 Niacin [2] Niacin; Nicotinic acid[1] D00049 --[4] 6, 78, 79, 265
23 Omega-3 fatty acids [6] Omega 3 fatty acids; Omega-3; Omega-3 fatty acid; Omega-3 fatty acids; OMEGA-3-ACID TRIGLYCERIDES; Phospholipids---[8] 13, 46, 49, 53, 66, 79, 96, 299
24 Pravastatin [2] Pravastatin; Pravastatin sodium[2] D00893 ,
D08410 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333
25 Prednisone [3] Prednisona; Prednisone; RAYOS[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
26 Rosuvastatin [3] Crestor; Rosuvastatin; Rosuvastatin calcium[2] D01915 ,
D08492 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
27 Simvastatin [3] Simvastatin; Simvastatina; Simvastatine[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
28 Sulfate ion [1] Sulfate---[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 79, 85, 86, 96, 111, 218, 222, 226, 265, 296, 297, 299
29 TAK-475 [1] TAK-475---[1] 79