Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetate [1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
2 Acetazolamide [1] Acetazolamide[2] D00218 ,
D01196 		[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[8] 13, 86, 90, 115, 154, 155, 225, 230
3 Amiloride [3] Amiloride; Amiloride Hydrochloride; Midamor[2] D00649 ,
D07447 		[3] SCNN1A,
SCNN1B,
SCNN1G 💬		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[4] 13, 67, 225, 299
4 Atorvastatin [3] Atorvastatin; Atorvastatin Calcium; Lipitor[3] D00258 ,
D00887 ,
D07474 		[1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[18] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299
5 Chlorothiazide [1] Chlorothiazide[2] D00519 ,
D03471 		[1] SLC12A3 💬-[1] 225
6 Desmopressin [5] DDAVP; Desmopressin; Desmopressin acetate; Desmopressine; Minirin[2] D00291 ,
D02235 		[2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[6] 6, 64, 72, 75, 225, 288
7 Fluconazole [2] Diflucan; FLUCONAZOLE[2] D00322 ,
D01429 		--[2] 96, 225
8 Hydrochlorothiazide [2] Esidrix; Hydrochlorothiazide[1] D00340 [1] SLC12A3 💬-[4] 13, 67, 225, 235
9 Indomethacin [2] INDOMETACIN; Indomethacin[3] D00141 ,
D01565 ,
D02110 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 225, 271, 298
10 Magnesium [1] Magnesium---[21] 3, 6, 11, 13, 15, 46, 51, 64, 70, 93, 97, 111, 166, 225, 235, 256, 284, 291, 296, 297, 298
11 Metformin [5] Metformin; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine[2] D00944 ,
D04966 		[2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
12 Omeprazole [5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM[4] D00455 ,
D01207 ,
D05259 ,
D05261 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
13 Riociguat [2] Adempas; Riociguat[1] D09572 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[6] 51, 84, 86, 88, 225, 299
14 Salmon, unspecified [1] Salmon---[3] 96, 97, 225
15 Sevoflurane [1] Sevoflurane[1] D00547 --[7] 6, 21, 22, 34, 98, 225, 296
16 Sildenafil [6] Mysildecard; Revatio; Sildenafil; Sildenafil Citrate; SILDENAFILO; Viagra[2] D02229 ,
D08514 		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
17 Spironolactone [1] Spironolactone[1] D00443 [1] NR3C2 💬[1] Aldosterone-regulated sodium reabsorption 💬[7] 58, 67, 86, 113, 210, 218, 225
18 Tolvaptan [3] Jinarc; Samsca; TOLVAPTAN[1] D01213 [1] AVPR2 💬[3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[3] 67, 72, 225