Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acarbose [1] Acarbose[1] D00216 [5] AMY2A,
AMY2B,
GAA,
GANC,
MGAM 💬		[7] Carbohydrate digestion and absorption, Galactose metabolism, Lysosome, Metabolic pathways, Pancreatic secretion, Salivary secretion, Starch and sucrose metabolism 💬[1] 298
2 Acetate [1] Acetate---[43] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
3 Acetylcarnitine [2] Acetyl-L-carnitine; Acetylcarnitine---[3] 2, 265, 298
4 Acetylcysteine [3] Acetylcysteine; Mucomyst; N-acetylcysteine[1] D00221 --[20] 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
5 Activated charcoal [1] Carbon---[9] 6, 46, 50, 51, 85, 86, 96, 97, 298
6 Alanine [2] Alanine; L-alanine[1] D00012 --[5] 6, 13, 251, 298, 299
7 Alpha-1-proteinase inhibitor [6] Alpha 1-Antitrypsin; Alpha 1-Proteinase Inhibitor; ALPHA-1-ANTITRYPSIN; Alpha1-Proteinase Inhibitor; Glassia; Prolastin-C---[3] 231, 298, 299
8 Amino acids [1] Amino acids---[3] 70, 240, 298
9 Amlodipine [1] Amlodipine[3] D00615 ,
D02914 ,
D07450 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 13, 51, 67, 298
10 Ascorbic acid [4] Acidum ascorbicum; Ascorbic acid; Iron; Vitamin C[1] D00018 --[8] 10, 97, 192, 206, 210, 211, 212, 298
11 Bentiromide [0] [1] D01346 --[6] 51, 89, 113, 117, 298, 299
12 Bupivacaine [2] Bupivacaine; BUPIVACAINE HYDROCHLORIDE[2] D01450 ,
D07552 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[8] 46, 51, 53, 70, 96, 168, 226, 298
13 Buprenorphine [1] Buprenorphine[2] D00836 ,
D07132 		[2] OPRK1,
OPRM1 💬		[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[3] 46, 70, 298
14 Calcium [2] Calcio; Calcium---[30] 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
15 Carbon monoxide [1] Carbon Monoxide[1] D09706 --[8] 6, 13, 53, 70, 85, 86, 149, 298
16 Cholecalciferol [5] Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[25] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
17 Diazepam [1] Diazepam[1] D00293 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 46, 155, 298
18 Dronabinol [4] DELTA-9-TETRAHYDROCANNABINOL; Dronabinol; Sativex; Tetrahydrocannabinol[1] D00306 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[8] 2, 8, 13, 36, 46, 96, 271, 298
19 Esomeprazole [3] Esomeprazole; Nexium; Omeprazole[4] D01984 ,
D04056 ,
D07917 ,
D09339 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[8] 13, 46, 86, 98, 107, 113, 298, 299
20 Etanercept [4] Benepali; ENBREL; Erelzi; Etanercept[1] D00742 [2] LTA,
TNF 💬		[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
21 Ethanol [3] Alcohol; Ethanol; Prednisone[4] D00068 ,
D02798 ,
D04855 ,
D06542 		--[7] 13, 51, 58, 97, 279, 280, 298
22 Gabapentin [4] Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN[1] D00332 [5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298
23 Gold [1] Gold---[43] 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318
24 Hemoglobin [1] Hemoglobin---[1] 298
25 Hydroxychloroquine [3] Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE; PLAQUENIL[1] D08050 --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299
26 Indomethacin [2] INDOMETACIN; Indomethacin[3] D00141 ,
D01565 ,
D02110 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 225, 271, 298
27 Lanreotide [3] Lanreotide; LANREOTIDE ACETATE; Somatuline Autogel---[4] 67, 73, 85, 298
28 Levocarnitine [4] Carnitine; L-Carnitine; Levocarnitine; Xyzal[3] D02030 ,
D02176 ,
D04713 		--[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316
29 Magnesium [1] Magnesium---[21] 3, 6, 11, 13, 15, 46, 51, 64, 70, 93, 97, 111, 166, 225, 235, 256, 284, 291, 296, 297, 298
30 Magnesium aspartate [1] Magnesium aspartate[1] D02026 --[1] 298
31 Magnesium aspartate hydrochloride [1] MAGNESIUM ASPARTATE HYDROCHLORIDE---[1] 298
32 Meperidine [1] Pethidine[2] D01383 ,
D08343 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 298
33 Metamizole [1] Metamizole[1] D08188 --[1] 298
34 Methamidophos [1] MONITOR---[20] 2, 11, 13, 19, 28, 46, 49, 58, 65, 70, 81, 85, 86, 98, 113, 118, 129, 298, 299, 300
35 Methionine [3] Butanoic acid; L-methionine; Methionine[2] D00019 ,
D04983 		--[7] 34, 75, 84, 93, 229, 298, 300
36 Midazolam [2] Midazolam; Midazolam injection[3] D00550 ,
D00696 ,
D05028 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
37 Morphine [2] Morphine; MORPHINE SULFATE[3] D00842 ,
D02271 ,
D08233 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[6] 36, 46, 70, 85, 86, 298
38 MS-1819 [1] MS1819-SD---[2] 298, 299
39 Omeprazole [5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM[4] D00455 ,
D01207 ,
D05259 ,
D05261 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
40 Oxycodone [3] Oxycodone; OXYCODONE HYDROCHLORIDE; Oxycodone/Acetaminophen[3] D03783 ,
D05312 ,
D05462 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298
41 Pancrelipase [2] Pancreatin; Pancrelipase[1] D05349 --[2] 298, 299
42 Pentoxifylline [1] Pentoxifylline[1] D00501 --[10] 26, 56, 84, 93, 96, 113, 220, 222, 296, 298
43 Perflubutane [1] Perflubutane[1] D05440 --[2] 298, 300
44 Pioglitazone [1] Pioglitazone[2] D00945 ,
D08378 		[1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
45 Pregabalin [2] Lyrica; Pregabalin[1] D02716 [4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298
46 Reparixin [1] Reparixin[1] D08984 [2] CXCR1,
CXCR2 💬		[7] Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, Human cytomegalovirus infection, Phospholipase D signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬[2] 298, 299
47 Secretin human [3] Human Secretin; Secretin; Synthetic human secretin---[1] 298
48 Selenium [1] SELENIUM---[4] 13, 96, 278, 298
49 Simvastatin [3] SIMVASTATIN; Simvastatina; Simvastatine[1] D00434 [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
50 Sulfanilamide [0] [1] D08543 --[5] 6, 30, 60, 118, 298
51 Tanezumab [1] Tanezumab[1] D09387 [1] NGF 💬[9] Apoptosis, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[2] 226, 298
52 Thalidomide [1] Thalidomide[1] D00754 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
53 Tocopherol [2] Tocoferol; Tocopherol[1] D02332 --[6] 13, 49, 90, 206, 257, 298
54 Triamcinolone [4] Kenalog; Naltrexone; Triamcinolone; TRIAMCINOLONE ACETONIDE[5] D00385 ,
D00983 ,
D00984 ,
D00985 ,
D06216 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
55 Trimethoprim [2] Bactrim; Trimethoprim[2] D00145 ,
D06236 		--[8] 36, 44, 49, 60, 61, 85, 298, 299
56 Tyrosine [4] Alanine; L-tyrosine; Propanoic acid; Tyrosine[1] D00022 --[5] 6, 75, 86, 111, 298
57 Vitamin D [3] Calciferol; Cod liver oil; Vitamin D---[24] 3, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299