Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 S1PR1 [3] FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10001 Fingolimod [3] 13, 14, 156
2 FCGRT - D11876 Efgartigimod alfa [3] 14, 35, 63
3 FCGRT - D12182 Rozanolixizumab [2] 14, 63
4 NR3C1 [1] Neuroactive ligand-receptor interaction D00292 Dexamethasone [24] 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
5 NR3C1 [1] Neuroactive ligand-receptor interaction D00407 Methylprednisolone [44] 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
6 NR3C1 [1] Neuroactive ligand-receptor interaction D00472 Prednisolone [40] 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
7 NR3C1 [1] Neuroactive ligand-receptor interaction D00473 Prednisone [44] 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
8 NR3C1 [1] Neuroactive ligand-receptor interaction D00751 Methylprednisolone [44] 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
9 NR3C1 [1] Neuroactive ligand-receptor interaction D00975 Dexamethasone [24] 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
10 NR3C1 [1] Neuroactive ligand-receptor interaction D00979 Methylprednisolone [44] 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
11 NR3C1 [1] Neuroactive ligand-receptor interaction D00980 Prednisolone [40] 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
12 NR3C1 [1] Neuroactive ligand-receptor interaction D00981 Prednisolone [40] 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
13 NR3C1 [1] Neuroactive ligand-receptor interaction D00982 Prednisolone [40] 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
14 NR3C1 [1] Neuroactive ligand-receptor interaction D01239 Prednisolone [40] 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
15 NR3C1 [1] Neuroactive ligand-receptor interaction D01510 Dexamethasone [24] 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
16 NR3C1 [1] Neuroactive ligand-receptor interaction D01615 Dexamethasone [24] 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
17 NR3C1 [1] Neuroactive ligand-receptor interaction D01632 Dexamethasone [24] 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
18 NR3C1 [1] Neuroactive ligand-receptor interaction D01948 Dexamethasone [24] 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
19 NR3C1 [1] Neuroactive ligand-receptor interaction D01998 Prednisolone [40] 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
20 NR3C1 [1] Neuroactive ligand-receptor interaction D02156 Prednisolone [40] 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
21 NR3C1 [1] Neuroactive ligand-receptor interaction D02174 Dexamethasone [24] 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
22 NR3C1 [1] Neuroactive ligand-receptor interaction D02591 Dexamethasone [24] 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
23 NR3C1 [1] Neuroactive ligand-receptor interaction D02592 Dexamethasone [24] 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
24 NR3C1 [1] Neuroactive ligand-receptor interaction D03301 Prednisolone [40] 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
25 NR3C1 [1] Neuroactive ligand-receptor interaction D05000 Methylprednisolone [44] 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
26 NR3C1 [1] Neuroactive ligand-receptor interaction D05001 Methylprednisolone [44] 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
27 NR3C1 [1] Neuroactive ligand-receptor interaction D05002 Methylprednisolone [44] 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
28 HRH1 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels D00665 Chlorpheniramine [1] 14
29 HRH1 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels D00668 Chlorpheniramine [1] 14
30 HRH1 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels D07398 Chlorpheniramine [1] 14
31 HRH1 [3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels D07803 Chlorpheniramine [1] 14
32 KCNA4 [2] Cortisol synthesis and secretion, Cushing syndrome D04127 Dalfampridine [5] 3, 4, 6, 13, 14
33 KCNC3 [1] Spinocerebellar ataxia D04127 Dalfampridine [1] 14
34 KCND2 [1] Serotonergic synapse D04127 Dalfampridine [1] 14
35 KCND3 [1] Spinocerebellar ataxia D04127 Dalfampridine [1] 14
36 MC2R [5] cAMP signaling pathway, Neuroactive ligand-receptor interaction, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome D00146 Corticotropin [15] 2, 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222
37 TOP2A [1] Platinum drug resistance D00125 Etoposide [9] 14, 26, 28, 34, 60, 65, 85, 164, 331
38 TOP2A [1] Platinum drug resistance D04107 Etoposide [9] 14, 26, 28, 34, 60, 65, 85, 164, 331
39 TOP2B [1] Platinum drug resistance D00125 Etoposide [9] 14, 26, 28, 34, 60, 65, 85, 164, 331
40 TOP2B [1] Platinum drug resistance D04107 Etoposide [9] 14, 26, 28, 34, 60, 65, 85, 164, 331
41 C5 [10] Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus D03940 Eculizumab [7] 11, 13, 14, 61, 62, 109, 222
42 MS4A1 [1] Hematopoietic cell lineage D02994 Rituximab [46] 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331