Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 cAMP signaling pathway 💬
 [2] ADORA1, ADORA2A 💬 D00045 💬 Adenosine [3] 13, 58, 65 💬
2 cAMP signaling pathway 💬
 [2] ADORA1, ADORA2A 💬 D02769 💬 Adenosine phosphate [1] 46 💬
3 cAMP signaling pathway 💬
 [9] ADORA1, ADORA2A, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D02017 💬 Theophylline [2] 236, 299 💬
4 cAMP signaling pathway 💬
 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D00528 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
5 cAMP signaling pathway 💬
 [8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D01453 💬 Caffeine [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
6 cAMP signaling pathway 💬
 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D00227 💬 Aminophylline [1] 63 💬
7 cAMP signaling pathway 💬
 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D05429 💬 Aminophylline [1] 63 💬
8 cAMP signaling pathway 💬
 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D00371 💬 Theophylline [2] 236, 299 💬
9 cAMP signaling pathway 💬
 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D01712 💬 Theophylline [2] 236, 299 💬
10 cAMP signaling pathway 💬
 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D06103 💬 Theophylline [2] 236, 299 💬
11 cAMP signaling pathway 💬
 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D06104 💬 Theophylline [2] 236, 299 💬
12 cAMP signaling pathway 💬
 [1] ADORA2A 💬 D04641 💬 Istradefylline [1]  6  💬
13 cAMP signaling pathway 💬
 [1] ADORA2A 💬 D09717 💬 Preladenant [1]  6  💬
14 cAMP signaling pathway 💬
 [1] ADORA2A 💬 D05711 💬 Regadenoson [1] 58 💬
15 cAMP signaling pathway 💬
 [1] ADORA2A 💬 D10174 💬 Tozadenant [1]  6  💬
16 cAMP signaling pathway 💬
 [1] ADRB1 💬 D00636 💬 Amiodarone [2] 28, 127 💬
17 cAMP signaling pathway 💬
 [1] ADRB1 💬 D02910 💬 Amiodarone [2] 28, 127 💬
18 cAMP signaling pathway 💬
 [1] ADRB1 💬 D00235 💬 Atenolol [1] 167 💬
19 cAMP signaling pathway 💬
 [1] ADRB1 💬 D00634 💬 Bisoprolol [3] 67, 86, 113 💬
20 cAMP signaling pathway 💬
 [1] ADRB1 💬 D02342 💬 Bisoprolol [3] 67, 86, 113 💬
21 cAMP signaling pathway 💬
 [1] ADRB1 💬 D07660 💬 Celiprolol [1] 168 💬
22 cAMP signaling pathway 💬
 [1] ADRB1 💬 D00632 💬 Dobutamine [3] 57, 58, 215 💬
23 cAMP signaling pathway 💬
 [1] ADRB1 💬 D03879 💬 Dobutamine [3] 57, 58, 215 💬
24 cAMP signaling pathway 💬
 [1] ADRB1 💬 D03880 💬 Dobutamine [3] 57, 58, 215 💬
25 cAMP signaling pathway 💬
 [1] ADRB1 💬 D03881 💬 Dobutamine [3] 57, 58, 215 💬
26 cAMP signaling pathway 💬
 [1] ADRB1 💬 D00644 💬 Esmolol [1] 58 💬
27 cAMP signaling pathway 💬
 [1] ADRB1 💬 D07916 💬 Esmolol [1] 58 💬
28 cAMP signaling pathway 💬
 [1] ADRB1 💬 D00601 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
29 cAMP signaling pathway 💬
 [1] ADRB1 💬 D02358 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
30 cAMP signaling pathway 💬
 [1] ADRB1 💬 D05011 💬 Metoprolol [6] 17, 57, 58, 113, 193, 226 💬
31 cAMP signaling pathway 💬
 [1] ADRB1 💬 D05127 💬 Nebivolol [4] 17, 85, 113, 167 💬
32 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00255 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
33 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D03415 💬 Carvedilol [5]  6 , 57, 86, 113, 210 💬
34 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D02349 💬 Dipivefrin [1]  6  💬
35 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D01277 💬 Droxidopa [5]  5 ,  6 , 17, 169, 170 💬
36 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00124 💬 Ephedrine [1] 11 💬
37 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00095 💬 Epinephrine [3] 46, 70, 96 💬
38 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00996 💬 Epinephrine [3] 46, 70, 96 💬
39 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D02149 💬 Epinephrine [3] 46, 70, 96 💬
40 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00432 💬 Nadolol [1]  6  💬
41 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00076 💬 Norepinephrine [1] 22 💬
42 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D05206 💬 Norepinephrine [1] 22 💬
43 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00483 💬 Propranolol [7]  6 , 158, 167, 215, 227, 278, 296 💬
44 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D08443 💬 Propranolol [7]  6 , 158, 167, 215, 227, 278, 296 💬
45 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00485 💬 Pseudoephedrine [1] 17 💬
46 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D05648 💬 Pseudoephedrine [1] 17 💬
47 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D05649 💬 Pseudoephedrine [1] 17 💬
48 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D08449 💬 Pseudoephedrine [1] 17 💬
49 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00378 💬 Timolol [2] 157, 227 💬
50 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D00603 💬 Timolol [2] 157, 227 💬
51 cAMP signaling pathway 💬
 [2] ADRB1, ADRB2 💬 D08600 💬 Timolol [2] 157, 227 💬
52 cAMP signaling pathway 💬
 [1] ADRB2 💬 D07713 💬 Clenbuterol [5]  1 ,  2 ,  6 , 13, 256 💬
53 cAMP signaling pathway 💬
 [1] ADRB2 💬 D01373 💬 Formoterol [3] 85, 228, 299 💬
54 cAMP signaling pathway 💬
 [1] ADRB2 💬 D05277 💬 Formoterol [3] 85, 228, 299 💬
55 cAMP signaling pathway 💬
 [1] ADRB2 💬 D07990 💬 Formoterol [3] 85, 228, 299 💬
56 cAMP signaling pathway 💬
 [1] ADRB2 💬 D08092 💬 Isoxsuprine [1] 13 💬
57 cAMP signaling pathway 💬
 [1] ADRB2 💬 D08124 💬 Levosalbutamol [1] 49 💬
58 cAMP signaling pathway 💬
 [1] ADRB2 💬 D02147 💬 Salbutamol [14]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 228, 231, 256, 299 💬
59 cAMP signaling pathway 💬
 [1] ADRB2 💬 D00687 💬 Salmeterol [1] 299 💬
60 cAMP signaling pathway 💬
 [1] ADRB2 💬 D05792 💬 Salmeterol [1] 299 💬
61 cAMP signaling pathway 💬
 [1] ADRB2 💬 D00688 💬 Terbutaline [1] 118 💬
62 cAMP signaling pathway 💬
 [1] ADRB2 💬 D08570 💬 Terbutaline [1] 118 💬
63 cAMP signaling pathway 💬
 [1] ADRB2 💬 D02151 💬 Tulobuterol [1]  6  💬
64 cAMP signaling pathway 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00297 💬 Digitoxin [1] 299 💬
65 cAMP signaling pathway 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 D00298 💬 Digoxin [3]  8 , 46, 210 💬
66 cAMP signaling pathway 💬
 [1] BRAF 💬 D10064 💬 Dabrafenib [1] 34 💬
67 cAMP signaling pathway 💬
 [2] BRAF, RAF1 💬 D06272 💬 Sorafenib [2] 34, 86 💬
68 cAMP signaling pathway 💬
 [2] BRAF, RAF1 💬 D08524 💬 Sorafenib [2] 34, 86 💬
69 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00615 💬 Amlodipine [4] 13, 51, 67, 298 💬
70 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02914 💬 Amlodipine [4] 13, 51, 67, 298 💬
71 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07450 💬 Amlodipine [4] 13, 51, 67, 298 💬
72 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01173 💬 Cilnidipine [1] 67 💬
73 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00616 💬 Diltiazem [3] 51, 58, 86 💬
74 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D03830 💬 Diltiazem [3] 51, 58, 86 💬
75 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D07845 💬 Diltiazem [3] 51, 58, 86 💬
76 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00349 💬 Isradipine [1]  6  💬
77 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00617 💬 Nicardipine [2] 70, 86 💬
78 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08270 💬 Nicardipine [2] 70, 86 💬
79 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00437 💬 Nifedipine [2] 50, 81 💬
80 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D01908 💬 Nilvadipine [1] 90 💬
81 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D05442 💬 Perhexiline [2] 58, 272 💬
82 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D08340 💬 Perhexiline [2] 58, 272 💬
83 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D00619 💬 Verapamil [3] 96, 140, 167 💬
84 cAMP signaling pathway 💬
 [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 D02356 💬 Verapamil [3] 96, 140, 167 💬
85 cAMP signaling pathway 💬
 [6] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2 💬 D08441 💬 Propiverine [1] 226 💬
86 cAMP signaling pathway 💬
 [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 D00537 💬 Topiramate [6]  6 , 97, 140, 144, 156, 193 💬
87 cAMP signaling pathway 💬
 [1] CFTR 💬 D11423 💬 Deutivacaftor [1] 299 💬
88 cAMP signaling pathway 💬
 [1] CFTR 💬 D11507 💬 Elexacaftor [1] 299 💬
89 cAMP signaling pathway 💬
 [1] CFTR 💬 D11724 💬 Galicaftor [1] 299 💬
90 cAMP signaling pathway 💬
 [1] CFTR 💬 D09916 💬 Ivacaftor [1] 299 💬
91 cAMP signaling pathway 💬
 [1] CFTR 💬 D10134 💬 Lumacaftor [1] 299 💬
92 cAMP signaling pathway 💬
 [1] CFTR 💬 D11041 💬 Tezacaftor [1] 299 💬
93 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00113 💬 Atropine [2]  2 , 299 💬
94 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D01077 💬 Atropine [2]  2 , 299 💬
95 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D02069 💬 Atropine [2]  2 , 299 💬
96 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D03011 💬 Atropine [2]  2 , 299 💬
97 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D03814 💬 Atropine [2]  2 , 299 💬
98 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D01000 💬 Bethanechol [1] 98 💬
99 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D11383 💬 Blarcamesine [1] 156 💬
100 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D02212 💬 Ipratropium [2]  6 , 86 💬
101 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00465 💬 Oxybutynin [3]  6 , 13, 53 💬
102 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00722 💬 Oxybutynin [3]  6 , 13, 53 💬
103 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00481 💬 Propantheline [1] 26 💬
104 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00765 💬 Rocuronium [1] 296 💬
105 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00138 💬 Scopolamine [1]  2  💬
106 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00787 💬 Trihexyphenidyl [2]  5 ,  6  💬
107 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D08638 💬 Trihexyphenidyl [2]  5 ,  6  💬
108 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 D00397 💬 Tropicamide [3]  6 , 13, 19 💬
109 cAMP signaling pathway 💬
 [3] CHRM1, CHRM2, DRD2 💬 D00270 💬 Chlorpromazine [1] 254 💬
110 cAMP signaling pathway 💬
 [3] CHRM1, CHRM2, DRD2 💬 D00789 💬 Chlorpromazine [1] 254 💬
111 cAMP signaling pathway 💬
 [3] CHRM1, CHRM2, DRD2 💬 D03274 💬 Chlorpromazine [1] 254 💬
112 cAMP signaling pathway 💬
 [3] CHRM1, CHRM2, DRD2 💬 D04034 💬 Chlorpromazine [1] 254 💬
113 cAMP signaling pathway 💬
 [1] CHRM2 💬 D07226 💬 Fesoterodine [1]  6  💬
114 cAMP signaling pathway 💬
 [1] CHRM2 💬 D00525 💬 Pilocarpine [3]  6 , 53, 299 💬
115 cAMP signaling pathway 💬
 [1] CHRM2 💬 D02200 💬 Pilocarpine [3]  6 , 53, 299 💬
116 cAMP signaling pathway 💬
 [1] CHRM2 💬 D05478 💬 Pilocarpine [3]  6 , 53, 299 💬
117 cAMP signaling pathway 💬
 [2] CRHR1, CRHR2 💬 D03905 💬 Corticorelin [2] 75, 205 💬
118 cAMP signaling pathway 💬
 [2] CRHR1, CRHR2 💬 D03592 💬 Corticorelin ovine triflutate [1] 75 💬
119 cAMP signaling pathway 💬
 [2] DRD1, DRD2 💬 D02004 💬 Apomorphine [3]  5 ,  6 ,  7  💬
120 cAMP signaling pathway 💬
 [2] DRD1, DRD2 💬 D07460 💬 Apomorphine [3]  5 ,  6 ,  7  💬
121 cAMP signaling pathway 💬
 [2] DRD1, DRD2 💬 D01044 💬 Flupentixol [1] 97 💬
122 cAMP signaling pathway 💬
 [2] DRD1, DRD2 💬 D00502 💬 Pergolide [1]  6  💬
123 cAMP signaling pathway 💬
 [2] DRD1, DRD2 💬 D08339 💬 Pergolide [1]  6  💬
124 cAMP signaling pathway 💬
 [3] DRD1, DRD2, DRD5 💬 D09886 💬 Dexpramipexole [1]  2  💬
125 cAMP signaling pathway 💬
 [3] DRD1, DRD2, DRD5 💬 D00633 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
126 cAMP signaling pathway 💬
 [3] DRD1, DRD2, DRD5 💬 D07870 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
127 cAMP signaling pathway 💬
 [3] DRD1, DRD2, DRD5 💬 D11839 💬 Foslevodopa [1]  6  💬
128 cAMP signaling pathway 💬
 [3] DRD1, DRD2, DRD5 💬 D00059 💬 Levodopa [8]  2 ,  4 ,  6 , 17, 90, 140, 164, 201 💬
129 cAMP signaling pathway 💬
 [2] DRD1, DRD5 💬 D11431 💬 Tavapadon [1]  6  💬
130 cAMP signaling pathway 💬
 [1] DRD2 💬 D00780 💬 Bromocriptine [2]  6 , 74 💬
131 cAMP signaling pathway 💬
 [1] DRD2 💬 D03165 💬 Bromocriptine [2]  6 , 74 💬
132 cAMP signaling pathway 💬
 [1] DRD2 💬 D00987 💬 Cabergoline [3]  6 , 74, 75 💬
133 cAMP signaling pathway 💬
 [1] DRD2 💬 D01745 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
134 cAMP signaling pathway 💬
 [1] DRD2 💬 D07868 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
135 cAMP signaling pathway 💬
 [1] DRD2 💬 D00136 💬 Haloperidol [1]  8  💬
136 cAMP signaling pathway 💬
 [1] DRD2 💬 D01898 💬 Haloperidol [1]  8  💬
137 cAMP signaling pathway 💬
 [1] DRD2 💬 D01462 💬 Lisuride [2]  6 , 86 💬
138 cAMP signaling pathway 💬
 [1] DRD2 💬 D08132 💬 Lisuride [2]  6 , 86 💬
139 cAMP signaling pathway 💬
 [1] DRD2 💬 D07309 💬 Melperone [1]  6  💬
140 cAMP signaling pathway 💬
 [1] DRD2 💬 D00726 💬 Metoclopramide [1] 51 💬
141 cAMP signaling pathway 💬
 [1] DRD2 💬 D02213 💬 Metoclopramide [1] 51 💬
142 cAMP signaling pathway 💬
 [1] DRD2 💬 D05008 💬 Metoclopramide [1] 51 💬
143 cAMP signaling pathway 💬
 [1] DRD2 💬 D00560 💬 Pimozide [1]  2  💬
144 cAMP signaling pathway 💬
 [1] DRD2 💬 D07305 💬 Piribedil [1]  6  💬
145 cAMP signaling pathway 💬
 [1] DRD2 💬 D00559 💬 Pramipexole [3]  2 ,  6 , 20 💬
146 cAMP signaling pathway 💬
 [1] DRD2 💬 D05575 💬 Pramipexole [3]  2 ,  6 , 20 💬
147 cAMP signaling pathway 💬
 [1] DRD2 💬 D09953 💬 Pridopidine [3]  2 ,  6 ,  8  💬
148 cAMP signaling pathway 💬
 [1] DRD2 💬 D00458 💬 Quetiapine [2]  6 , 13 💬
149 cAMP signaling pathway 💬
 [1] DRD2 💬 D08456 💬 Quetiapine [2]  6 , 13 💬
150 cAMP signaling pathway 💬
 [1] DRD2 💬 D00426 💬 Risperidone [5]  8 , 156, 179, 187, 206 💬
151 cAMP signaling pathway 💬
 [1] DRD2 💬 D00784 💬 Ropinirole [4]  2 ,  6 , 74, 309 💬
152 cAMP signaling pathway 💬
 [1] DRD2 💬 D08489 💬 Ropinirole [4]  2 ,  6 , 74, 309 💬
153 cAMP signaling pathway 💬
 [1] DRD2 💬 D05768 💬 Rotigotine [2]  6 , 127 💬
154 cAMP signaling pathway 💬
 [1] DRD2 💬 D01226 💬 Sulpiride [5]  2 ,  6 , 17, 46, 70 💬
155 cAMP signaling pathway 💬
 [1] DRD2 💬 D08549 💬 Sulpiride [5]  2 ,  6 , 17, 46, 70 💬
156 cAMP signaling pathway 💬
 [1] DRD2 💬 D01348 💬 Terguride [2] 51, 86 💬
157 cAMP signaling pathway 💬
 [1] DRD2 💬 D08590 💬 Tiapride [1]  8  💬
158 cAMP signaling pathway 💬
 [1] DRD2 💬 D00799 💬 Trifluoperazine [2] 283, 284 💬
159 cAMP signaling pathway 💬
 [1] DRD2 💬 D01448 💬 Trifluoperazine [2] 283, 284 💬
160 cAMP signaling pathway 💬
 [1] DRD2 💬 D08636 💬 Trifluoperazine [2] 283, 284 💬
161 cAMP signaling pathway 💬
 [2] DRD2, HTR1A 💬 D01164 💬 Aripiprazole [2]  6 , 206 💬
162 cAMP signaling pathway 💬
 [2] DRD2, HTR1A 💬 D00702 💬 Buspirone [3]  6 , 51, 179 💬
163 cAMP signaling pathway 💬
 [2] DRD2, HTR1A 💬 D07593 💬 Buspirone [3]  6 , 51, 179 💬
164 cAMP signaling pathway 💬
 [2] DRD2, HTR1A 💬 D09997 💬 Cariprazine [1] 21 💬
165 cAMP signaling pathway 💬
 [2] DRD2, HTR1A 💬 D09397 💬 Pardoprunox [1]  6  💬
166 cAMP signaling pathway 💬
 [2] DRD2, HTR6 💬 D00454 💬 Olanzapine [2]  2 ,  8  💬
167 cAMP signaling pathway 💬
 [2] DRD2, HTR6 💬 D06623 💬 Olanzapine [2]  2 ,  8  💬
168 cAMP signaling pathway 💬
 [1] EDNRA 💬 D07077 💬 Ambrisentan [7] 51, 84, 85, 86, 88, 210, 211 💬
169 cAMP signaling pathway 💬
 [1] EDNRA 💬 D01227 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
170 cAMP signaling pathway 💬
 [1] EDNRA 💬 D07538 💬 Bosentan [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
171 cAMP signaling pathway 💬
 [1] EDNRA 💬 D10135 💬 Macitentan [5] 51, 85, 86, 88, 210 💬
172 cAMP signaling pathway 💬
 [1] EDNRA 💬 D07171 💬 Sitaxentan [1] 86 💬
173 cAMP signaling pathway 💬
 [1] EDNRA 💬 D11776 💬 Sparsentan [3] 66, 218, 222 💬
174 cAMP signaling pathway 💬
 [1] EDNRA 💬 D07741 💬 Zibotentan [1] 51 💬
175 cAMP signaling pathway 💬
 [2] GABBR1, GABBR2 💬 D09791 💬 Arbaclofen [2] 13, 206 💬
176 cAMP signaling pathway 💬
 [2] GABBR1, GABBR2 💬 D08861 💬 Arbaclofen Placarbil [1] 13 💬
177 cAMP signaling pathway 💬
 [2] GABBR1, GABBR2 💬 D00241 💬 Baclofen [7]  2 , 10, 13, 18, 65, 149, 206 💬
178 cAMP signaling pathway 💬
 [1] GHSR 💬 D10563 💬 Macimorelin [1] 78 💬
179 cAMP signaling pathway 💬
 [1] GLP1R 💬 D09889 💬 Dulaglutide [2] 13, 299 💬
180 cAMP signaling pathway 💬
 [1] GLP1R 💬 D04121 💬 Exenatide [6]  6 , 17, 72, 78, 193, 233 💬
181 cAMP signaling pathway 💬
 [1] GLP1R 💬 D06404 💬 Liraglutide [3]  6 , 75, 193 💬
182 cAMP signaling pathway 💬
 [1] GLP1R 💬 D09729 💬 Lixisenatide [1]  6  💬
183 cAMP signaling pathway 💬
 [1] GLP1R 💬 D10025 💬 Semaglutide [1]  6  💬
184 cAMP signaling pathway 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 D08964 💬 Perampanel [3]  2 ,  6 , 144 💬
185 cAMP signaling pathway 💬
 [4] GRIA1, GRIA2, GRIA3, GRIA4 💬 D02696 💬 Talampanel [2]  2 ,  6  💬
186 cAMP signaling pathway 💬
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00775 💬 Riluzole [9]  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
187 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D02780 💬 Acamprosate [2]  6 , 206 💬
188 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07058 💬 Acamprosate [2]  6 , 206 💬
189 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00777 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
190 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07441 💬 Amantadine [4]  6 ,  8 , 13, 127 💬
191 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00848 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
192 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03742 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
193 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D03744 💬 Dextromethorphan [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
194 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine [3]  2 ,  4 , 70 💬
195 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D00711 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
196 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
197 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D09917 💬 Latrepirdine [1]  8  💬
198 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D04905 💬 Memantine [7]  2 ,  6 ,  8 , 13, 49, 127, 205 💬
199 cAMP signaling pathway 💬
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08174 💬 Memantine [7]  2 ,  6 ,  8 , 13, 49, 127, 205 💬
200 cAMP signaling pathway 💬
 [1] HTR1A 💬 D10184 💬 Vortioxetine [1]  6  💬
201 cAMP signaling pathway 💬
 [2] HTR1B, HTR1D 💬 D00415 💬 Zolmitriptan [1]  6  💬
202 cAMP signaling pathway 💬
 [1] HTR4 💬 D00274 💬 Cisapride [1] 13 💬
203 cAMP signaling pathway 💬
 [1] HTR4 💬 D02092 💬 Cisapride [1] 13 💬
204 cAMP signaling pathway 💬
 [1] HTR4 💬 D08236 💬 Mosapride [1] 96 💬
205 cAMP signaling pathway 💬
 [1] HTR4 💬 D09205 💬 Prucalopride [3] 13, 51, 96 💬
206 cAMP signaling pathway 💬
 [1] HTR4 💬 D09693 💬 Velusetrag [1] 99 💬
207 cAMP signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10604 💬 Binimetinib [1] 34 💬
208 cAMP signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10405 💬 Cobimetinib [1] 280 💬
209 cAMP signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D09666 💬 Selumetinib [1] 34 💬
210 cAMP signaling pathway 💬
 [2] MAP2K1, MAP2K2 💬 D10175 💬 Trametinib [4]  2 , 34, 279, 280 💬
211 cAMP signaling pathway 💬
 [1] MC2R 💬 D00146 💬 Corticotropin [15]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222 💬
212 cAMP signaling pathway 💬
 [1] MC2R 💬 D00284 💬 Tetracosactide [5] 78, 83, 113, 145, 222 💬
213 cAMP signaling pathway 💬
 [1] NFKB1 💬 D01146 💬 Iguratimod [4] 46, 51, 53, 271 💬
214 cAMP signaling pathway 💬
 [1] NPR1 💬 D04051 💬 Erythrityl tetranitrate [1] 46 💬
215 cAMP signaling pathway 💬
 [1] NPR1 💬 D05147 💬 Nesiritide [2] 46, 58 💬
216 cAMP signaling pathway 💬
 [1] OXTR 💬 D03008 💬 Atosiban [1] 118 💬
217 cAMP signaling pathway 💬
 [1] OXTR 💬 D07229 💬 Carbetocin [1] 193 💬
218 cAMP signaling pathway 💬
 [1] OXTR 💬 D00089 💬 Oxytocin [6]  6 , 72, 127, 193, 206, 226 💬
219 cAMP signaling pathway 💬
 [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D07546 💬 Bucladesine [1] 246 💬
220 cAMP signaling pathway 💬
 [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D00718 💬 Flavoxate [1] 226 💬
221 cAMP signaling pathway 💬
 [7] PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D07961 💬 Flavoxate [1] 226 💬
222 cAMP signaling pathway 💬
 [2] PDE3A, PDE3B 💬 D01896 💬 Cilostazol [3] 51, 70, 124 💬
223 cAMP signaling pathway 💬
 [2] PDE3A, PDE3B 💬 D04720 💬 Levosimendan [1]  2  💬
224 cAMP signaling pathway 💬
 [2] PDE3A, PDE3B 💬 D00417 💬 Milrinone [1] 294 💬
225 cAMP signaling pathway 💬
 [2] PDE3A, PDE3B 💬 D02085 💬 Milrinone [1] 294 💬
226 cAMP signaling pathway 💬
 [6] PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 D01385 💬 Ibudilast [2]  2 , 13 💬
227 cAMP signaling pathway 💬
 [1] PDE4A 💬 D00302 💬 Dipyridamole [6] 46, 49, 51, 66, 96, 224 💬
228 cAMP signaling pathway 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D08860 💬 Apremilast [7] 46, 50, 56, 97, 107, 162, 271 💬
229 cAMP signaling pathway 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D05744 💬 Roflumilast [2] 84, 299 💬
230 cAMP signaling pathway 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 D01783 💬 Rolipram [2]  8 , 13 💬
231 cAMP signaling pathway 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 D11158 💬 Leniolisib [2] 53, 65 💬
232 cAMP signaling pathway 💬
 [1] PIK3CD 💬 D11437 💬 Parsaclisib [3] 35, 53, 61 💬
233 cAMP signaling pathway 💬
 [1] PPARA 💬 D01366 💬 Bezafibrate [7] 20, 93, 94, 160, 296, 316, 324 💬
234 cAMP signaling pathway 💬
 [1] PPARA 💬 D11208 💬 Elafibranor [1] 93 💬
235 cAMP signaling pathway 💬
 [1] PPARA 💬 D00565 💬 Fenofibrate [5]  8 , 79, 93, 94, 265 💬
236 cAMP signaling pathway 💬
 [1] PPARA 💬 D10711 💬 Pemafibrate [1] 93 💬
237 cAMP signaling pathway 💬
 [2] PTGER2, PTGER3 💬 D00419 💬 Misoprostol [3] 46, 70, 271 💬
238 cAMP signaling pathway 💬
 [1] RELA 💬 D12181 💬 Edasalonexent [1] 113 💬
239 cAMP signaling pathway 💬
 [2] ROCK1, ROCK2 💬 D07941 💬 Fasudil [4]  2 ,  5 ,  7 , 51 💬
240 cAMP signaling pathway 💬
 [1] ROCK2 💬 D11815 💬 Belumosudil [1] 51 💬
241 cAMP signaling pathway 💬
 [3] SSTR1, SSTR2, SSTR5 💬 D10147 💬 Pasireotide [3] 67, 74, 75 💬
242 cAMP signaling pathway 💬
 [3] SSTR1, SSTR2, SSTR5 💬 D07431 💬 Somatostatin [2] 67, 78 💬
243 cAMP signaling pathway 💬
 [1] SSTR2 💬 D00442 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬
244 cAMP signaling pathway 💬
 [1] SSTR2 💬 D06495 💬 Octreotide [7] 67, 75, 84, 85, 89, 193, 227 💬