Target Gene/Pathway Pathway / Gene


Search results


No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MAPK14 [1] Yersinia infection D09639 Losmapimod [2] 113, 222
2 MAPK14 [1] Yersinia infection D10959 Neflamapimod [1] 8
3 IL1B [1] Yersinia infection D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
4 IL1B [1] Yersinia infection D06635 Rilonacept [4] 51, 106, 107, 266
5 IL1B [1] Yersinia infection D09315 Canakinumab [10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
6 IL1B [1] Yersinia infection D09911 Gevokizumab [4] 41, 50, 56, 269
7 IL6 [1] Yersinia infection D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
8 IL6 [1] Yersinia infection D08976 Pomalidomide [6] 28, 34, 51, 85, 227, 331
9 IL6 [1] Yersinia infection D09669 Siltuximab [2] 28, 331
10 IL6 [1] Yersinia infection D10080 Sirukumab [2] 41, 46
11 IL10 [1] Yersinia infection D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
12 ITGA4 [1] Yersinia infection D06590 Firategrast [1] 13
13 ITGA4 [1] Yersinia infection D06886 Natalizumab [6] 13, 15, 25, 46, 63, 96
14 ITGA4 [1] Yersinia infection D08083 Vedolizumab [3] 94, 96, 97
15 ITGA4 [1] Yersinia infection D10540 Abrilumab [2] 96, 97
16 LCK [1] Yersinia infection D03658 Dasatinib [2] 51, 85
17 LCK [1] Yersinia infection D06414 Dasatinib [2] 51, 85
18 NFKB1 [1] Yersinia infection D01146 Iguratimod [4] 46, 51, 53, 271
19 PIK3CA [1] Yersinia infection D11158 Leniolisib [2] 53, 65
20 PIK3CB [1] Yersinia infection D11158 Leniolisib [2] 53, 65
21 PIK3CD [1] Yersinia infection D11158 Leniolisib [2] 53, 65
22 PIK3CD [1] Yersinia infection D11437 Parsaclisib [3] 35, 53, 61
23 MAPK11 [1] Yersinia infection D09639 Losmapimod [2] 113, 222
24 MAPK11 [1] Yersinia infection D10959 Neflamapimod [1] 8
25 MAPK13 [1] Yersinia infection D09639 Losmapimod [2] 113, 222
26 MAPK13 [1] Yersinia infection D10959 Neflamapimod [1] 8
27 MAP2K1 [1] Yersinia infection D09666 Selumetinib [1] 34
28 MAP2K1 [1] Yersinia infection D10175 Trametinib [4] 2, 34, 279, 280
29 MAP2K1 [1] Yersinia infection D10405 Cobimetinib [1] 280
30 MAP2K1 [1] Yersinia infection D10604 Binimetinib [1] 34
31 MAP2K2 [1] Yersinia infection D09666 Selumetinib [1] 34
32 MAP2K2 [1] Yersinia infection D10175 Trametinib [4] 2, 34, 279, 280
33 MAP2K2 [1] Yersinia infection D10405 Cobimetinib [1] 280
34 MAP2K2 [1] Yersinia infection D10604 Binimetinib [1] 34
35 RELA [1] Yersinia infection D12181 Edasalonexent [1] 113
36 ROCK1 [1] Yersinia infection D07941 Fasudil [4] 2, 5, 7, 51
37 MAPK12 [1] Yersinia infection D09639 Losmapimod [2] 113, 222
38 MAPK12 [1] Yersinia infection D10959 Neflamapimod [1] 8
39 CCL2 [1] Yersinia infection D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
40 SRC [1] Yersinia infection D03252 Bosutinib [2] 2, 67
41 SRC [1] Yersinia infection D03658 Dasatinib [2] 51, 85
42 SRC [1] Yersinia infection D06414 Dasatinib [2] 51, 85
43 SRC [1] Yersinia infection D09664 Saracatinib [3] 6, 89, 272
44 TNF [1] Yersinia infection D00742 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
45 TNF [1] Yersinia infection D00754 Thalidomide [20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
46 TNF [1] Yersinia infection D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
47 TNF [1] Yersinia infection D02597 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
48 TNF [1] Yersinia infection D02598 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
49 TNF [1] Yersinia infection D03441 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271
50 TNF [1] Yersinia infection D04358 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271
51 TNF [1] Yersinia infection D04687 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331
52 TNF [1] Yersinia infection D05393 Pegsunercept [1] 46
53 TNF [1] Yersinia infection D08976 Pomalidomide [6] 28, 34, 51, 85, 227, 331
54 TNF [1] Yersinia infection D09944 Ozoralizumab [1] 46
55 ROCK2 [1] Yersinia infection D07941 Fasudil [4] 2, 5, 7, 51
56 ROCK2 [1] Yersinia infection D11815 Belumosudil [1] 51