Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CCR4 [1] Viral protein interaction with cytokine and cytokine receptor D09761 Mogamulizumab [1] 26
2 CCR5 [1] Viral protein interaction with cytokine and cytokine receptor D06670 Maraviroc [2] 46, 84
3 CCR5 [1] Viral protein interaction with cytokine and cytokine receptor D09878 Cenicriviroc [1] 94
4 CSF1 [1] Viral protein interaction with cytokine and cytokine receptor D06402 Sunitinib [2] 28, 34
5 CSF1 [1] Viral protein interaction with cytokine and cytokine receptor D08552 Sunitinib [2] 28, 34
6 CSF1R [1] Viral protein interaction with cytokine and cytokine receptor D11270 Pexidartinib [1] 34
7 IL2RA [1] Viral protein interaction with cytokine and cytokine receptor D00748 Aldesleukin [6] 2, 35, 49, 65, 96, 97
8 IL2RA [1] Viral protein interaction with cytokine and cytokine receptor D03058 Basiliximab [6] 2, 50, 66, 97, 222, 228
9 IL2RA [1] Viral protein interaction with cytokine and cytokine receptor D03639 Daclizumab [8] 13, 56, 60, 65, 97, 107, 283, 284
10 IL2RB [1] Viral protein interaction with cytokine and cytokine receptor D00748 Aldesleukin [6] 2, 35, 49, 65, 96, 97
11 IL2RG [1] Viral protein interaction with cytokine and cytokine receptor D00748 Aldesleukin [6] 2, 35, 49, 65, 96, 97
12 IL6 [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
13 IL6 [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D08976 Pomalidomide [6] 28, 34, 51, 85, 227, 331
14 IL6 [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D09669 Siltuximab [2] 28, 331
15 IL6 [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D10080 Sirukumab [2] 41, 46
16 IL6R [1] Viral protein interaction with cytokine and cytokine receptor D02596 Tocilizumab [21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331
17 IL6R [1] Viral protein interaction with cytokine and cytokine receptor D10161 Sarilumab [5] 41, 46, 84, 107, 271
18 IL6R [1] Viral protein interaction with cytokine and cytokine receptor D11079 Satralizumab [2] 11, 13
19 CXCR1 [1] Viral protein interaction with cytokine and cytokine receptor D08984 Reparixin [2] 298, 299
20 CXCR2 [1] Viral protein interaction with cytokine and cytokine receptor D08984 Reparixin [2] 298, 299
21 IL10 [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
22 LTA [1] Viral protein interaction with cytokine and cytokine receptor D00742 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
23 LTA [1] Viral protein interaction with cytokine and cytokine receptor D10187 Pateclizumab [1] 46
24 IL20 [1] Viral protein interaction with cytokine and cytokine receptor D11756 Fletikumab [1] 46
25 CCL2 [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
26 TNF [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D00742 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
27 TNF [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D00754 Thalidomide [20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
28 TNF [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
29 TNF [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D02597 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
30 TNF [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D02598 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
31 TNF [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D03441 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271
32 TNF [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D04358 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271
33 TNF [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D04687 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331
34 TNF [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D05393 Pegsunercept [1] 46
35 TNF [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D08976 Pomalidomide [6] 28, 34, 51, 85, 227, 331
36 TNF [2] Viral protein interaction with cytokine and cytokine receptor, Yersinia infection D09944 Ozoralizumab [1] 46
37 CCR2 [1] Viral protein interaction with cytokine and cytokine receptor D09878 Cenicriviroc [1] 94
38 CXCR4 [1] Viral protein interaction with cytokine and cytokine receptor D08971 Plerixafor [6] 19, 20, 51, 65, 285, 299