Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Viral protein interaction with cytokine and cytokine receptor 💬
 [4] CCL2, IL10, IL6, TNF 💬 D01583 💬 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
2 Viral protein interaction with cytokine and cytokine receptor 💬
 [2] CCR2, CCR5 💬 D09878 💬 Cenicriviroc [1] 94 💬
3 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] CCR4 💬 D09761 💬 Mogamulizumab [1] 26 💬
4 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] CCR5 💬 D06670 💬 Maraviroc [2] 46, 84 💬
5 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] CSF1 💬 D06402 💬 Sunitinib [2] 28, 34 💬
6 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] CSF1 💬 D08552 💬 Sunitinib [2] 28, 34 💬
7 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] CSF1R 💬 D11270 💬 Pexidartinib [1] 34 💬
8 Viral protein interaction with cytokine and cytokine receptor 💬
 [2] CXCR1, CXCR2 💬 D08984 💬 Reparixin [2] 298, 299 💬
9 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] CXCR4 💬 D08971 💬 Plerixafor [6] 19, 20, 51, 65, 285, 299 💬
10 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL20 💬 D11756 💬 Fletikumab [1] 46 💬
11 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL2RA 💬 D03058 💬 Basiliximab [6]  2 , 50, 66, 97, 222, 228 💬
12 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL2RA 💬 D03639 💬 Daclizumab [8] 13, 56, 60, 65, 97, 107, 283, 284 💬
13 Viral protein interaction with cytokine and cytokine receptor 💬
 [3] IL2RA, IL2RB, IL2RG 💬 D00748 💬 Aldesleukin [6]  2 , 35, 49, 65, 96, 97 💬
14 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL6 💬 D09669 💬 Siltuximab [2] 28, 331 💬
15 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL6 💬 D10080 💬 Sirukumab [2] 41, 46 💬
16 Viral protein interaction with cytokine and cytokine receptor 💬
 [2] IL6, TNF 💬 D08976 💬 Pomalidomide [6] 28, 34, 51, 85, 227, 331 💬
17 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL6R 💬 D10161 💬 Sarilumab [5] 41, 46, 84, 107, 271 💬
18 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL6R 💬 D11079 💬 Satralizumab [2] 11, 13 💬
19 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] IL6R 💬 D02596 💬 Tocilizumab [21]  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
20 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] LTA 💬 D10187 💬 Pateclizumab [1] 46 💬
21 Viral protein interaction with cytokine and cytokine receptor 💬
 [2] LTA, TNF 💬 D00742 💬 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
22 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D02597 💬 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬
23 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D03441 💬 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271 💬
24 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D04358 💬 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271 💬
25 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D02598 💬 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
26 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D04687 💬 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331 💬
27 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D09944 💬 Ozoralizumab [1] 46 💬
28 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D05393 💬 Pegsunercept [1] 46 💬
29 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] TNF 💬 D00754 💬 Thalidomide [20]  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬