235. 副甲状腺機能低下症 Hypoparathyroidism Clinical trials / Disease details
臨床試験数 : 88 / 薬物数 : 128 - (DrugBank : 25) / 標的遺伝子数 : 5 - 標的パスウェイ数 : 7
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05117853 (ClinicalTrials.gov) | November 1, 2021 | 21/10/2021 | Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Thyroidectomy | The Use of Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Total Thyroidectomy: A Randomized Clinical Trial | Thyroid Disease;Hypoparathyroidism Postprocedural | Drug: Autofluorescent detection + Injection of indocyanine green;Procedure: Gold standard of visual identification and evaluation of viability of the parathyroid glands. | Onze Lieve Vrouw Hospital | NULL | Not yet recruiting | 18 Years | N/A | All | 300 | Phase 3 | Belgium |
| 2 | NCT05130476 (ClinicalTrials.gov) | October 1, 2021 | 8/11/2021 | Near-infrared Imaging Techniques for Identifying and Preserving Viable Parathyroid Glands During Thyroidectomy | Intraoperative Near-infrared Imaging Techniques for Identifying and Preserving Viable Parathyroid Glands During Total and Completion Thyroidectomy: a Matched Cohort Study | Hypoparathyroidism Postprocedural | Procedure: Near-infrared-induced autofluorescence and indocyanine green near-infrared angiography | Odense University Hospital | NULL | Recruiting | 18 Years | N/A | All | 139 | N/A | Denmark |
| 3 | NCT04785443 (ClinicalTrials.gov) | June 22, 2021 | 25/2/2021 | Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy | Contribution of Indocyanine Green Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy | Thyroid Diseases | Drug: ICG;Procedure: Control group | University Hospital, Brest | NULL | Recruiting | 18 Years | N/A | All | 242 | Phase 3 | France |
| 4 | EUCTR2020-005189-32-FR (EUCTR) | 09/02/2021 | 04/12/2020 | Contribution of indocyanine green angiography in the detection of parathyroids and the prevention of hypoparathyroidism post total thyroidectomy | Contribution of indocyanine green angiography in the detection of parathyroids and the prevention of hypoparathyroidism post total thyroidectomy - HYPOCAAVI | Thyroidectomy total MedDRA version: 20.0;Level: LLT;Classification code 10043777;Term: Thyroidectomy total;System Organ Class: 100000004865;Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Surgical Procedures, Operative [E04] | Trade Name: Infracyanine | CHRU de Brest | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 242 | Phase 3 | France | ||
| 5 | EUCTR2019-003506-26-ES (EUCTR) | 05/03/2020 | 14/01/2020 | Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy | Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy | Patients undergoing total thyroidectomy with visualization of the parathyroid glands under infrared light after intraoperative intravenous injection of 5 mg of indocyanine green to predict the possible occurrence of postoperative hypocalcemia MedDRA version: 20.1;Level: LLT;Classification code 10020949;Term: Hypocalcemia;System Organ Class: 100000004861 MedDRA version: 20.0;Classification code 10043777;Term: Thyroidectomy total;System Organ Class: 100000004865 MedDRA version: 21.0;Level: PT;Classification code 10080819;Term: Post procedural hypoparathyroidism;System Organ Class: 10022117 - Injury, poisoning and procedural complications;Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Surgical Procedures, Operative [E04] | Trade Name: Verde de Indocianina (Indocyanine Green) Product Name: Indocyanine Green INN or Proposed INN: Indocyanine green Other descriptive name: INDOCYANINE GREEN | Hospital Universitari Son Espases | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 40 | Phase 4 | Spain | ||
| 6 | NCT04012476 (ClinicalTrials.gov) | November 2016 | 28/6/2019 | Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy | Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy | Hypocalcemia;Total Thyroidectomy;Hypoparathyroidism Postprocedural | Drug: Indocyanine Green | Hospital Son Espases | Universitat de les Illes Balears | Recruiting | 18 Years | N/A | All | 40 | Phase 4 | Spain |