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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1100mcg rhPTH(1-84)1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
225mcg rhPTH(1-84)1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
350mcg rhPTH(1-84)1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
4A: PTH (1-84)----1件: 235
5Acetate1件: Acetate---43件: 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
6Alfacalcidol1件: Alfacalcidol1件: D01518 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬8件: 41, 46, 49, 50, 96, 107, 235, 238
7Allogenic parathyroid cells----1件: 235
8Amorphous calcium carbonate2件: Calcium,
Carbonate ion		---1件: 235
9Autofluorescent detection + Injection of indocyanine green1件: Indocyanine green1件: D01342 --1件: 235
10AZP-3601----1件: 235
11Betamethasone1件: Betamethasone7件: D00244 ,
D00972 ,
D01357 ,
D01402 ,
D01637 ,
D02032 ,
D02286 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬7件: 2, 28, 46, 83, 90, 96, 235
12Blood sample----18件: 8, 13, 46, 49, 51, 53, 61, 65, 66, 84, 96, 97, 107, 127, 235, 274, 288, 299
13Calcitriol1件: Calcitriol1件: D00129 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬9件: 18, 37, 46, 49, 66, 96, 158, 235, 326
14Calcitriol & Calcium2件: Calcitriol,
Calcium		1件: D00129 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬1件: 235
15Calcium1件: Calcium---30件: 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
16Calcium carbonate2件: Calcium,
Carbonate ion		---8件: 13, 19, 46, 53, 75, 96, 235, 299
17Calcium carbonate and alphacalcidol3件: Calcium,
Calcium carbonate,
Carbonate ion		2件: D00932 ,
D10802 		--1件: 235
18Calcium citrate2件: Calcium,
Calcium citrate		1件: D00933 --3件: 46, 84, 235
19Calcium gluconate2件: Calcium,
Calcium gluconate		1件: D00935 --3件: 214, 215, 235
20Calcium lactate2件: Calcium,
Calcium lactate		2件: D00936 ,
D02254 		--1件: 235
21Carbonate1件: Carbonate ion---12件: 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299
22CLTX-305----1件: 235
23Combination Product: TransCon PTH----1件: 235
24Control group----5件: 2, 34, 46, 70, 235
25Crystalline calcium supplements1件: Calcium---1件: 235
26Dexamethasone1件: Dexamethasone9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬25件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 283, 296, 299
27Dexamethasone oral tablet 8mg (Dexamethasone Krka tablets(8mg), Warsaw, Poland).1件: Dexamethasone9件: D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 235
28Diagnostic Test: Postoperative laboratory blood tests at 24 hour----1件: 235
29Diagnostic Test: Postoperative laboratory blood tests at 6 hour----1件: 235
30Diagnostic Test: Postoperative laboratory drainage fluid tests at 24 hour----1件: 235
31Diagnostic Test: Preoparative blood laboratory tests----1件: 235
32Diagnostic Test: PTH measurements post-thyroidectomy (at 5 and 60 min post thyroid removal)----1件: 235
33EB612 (EBP05)----1件: 235
34EnteraBio's Oral Parathyroid Hormone (1-34)1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
35Esidrex----1件: 235
36ESIDREX-R----1件: 235
37ESIDREX-R 25 mg----1件: 235
38Ether1件: Diethyl ether1件: D01772 --1件: 235
39Forsteo1件: Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬3件: 70, 235, 274
40FORSTEO-R1件: Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
41Gold1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 171, 193, 218, 222, 224, 227, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318
42Gold standard of visual identification and evaluation of viability of the parathyroid glands.1件: Gold---1件: 235
43Human recombinant parathyroid Hormone1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
44HYDROCHLOROTHIAZIDE1件: Hydrochlorothiazide1件: D00340 1件: SLC12A3 💬-4件: 13, 67, 225, 235
45ICG----3件: 93, 94, 235
46Immediate post operative bioassay of Parathyroid Hormone1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
47Indocyanine green1件: Indocyanine green1件: D01342 --8件: 22, 46, 51, 96, 235, 278, 291, 296
48Infracyanine----1件: 235
49INN Parathyroid Hormone (1-84) human1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
50Magnesium1件: Magnesium---19件: 3, 6, 11, 13, 15, 46, 64, 70, 93, 97, 166, 225, 235, 256, 284, 291, 296, 297, 298
51Natpar1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
52Natpara----1件: 235
53NATPARA/NATPAR1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
54Near-infrared-induced autofluorescence and indocyanine green near-infrared angiography1件: Indocyanine green1件: D01342 --1件: 235
55NPSP 558----1件: 235
56NPSP558----1件: 235
57Open-label PTH(1-84)----1件: 235
58ORMONE PARATIROIDEO DA DNA RICOMBINANTE----1件: 235
59Other: Empiric use of Calcium Carbonate and Calcitriol4件: Calcitriol,
Calcium,
Calcium carbonate,
Carbonate ion		3件: D00129 ,
D00932 ,
D10802 		1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬1件: 235
60Other: Postoperative nausea and vomiting at 24 hour----1件: 235
61Other: Postoperative nausea and vomiting at 6 hour----1件: 235
62Other: Postoperative pain at 24 hour----1件: 235
63Other: Postoperative pain at 6 hour----1件: 235
64Other: Postoperative sore throat and hoarseness at 24 hour----1件: 235
65Other: Postoperative sore throat and hoarseness at 6 hour----1件: 235
66Other: PTH based Calcium Carbonate and Calcitriol repletion4件: Calcitriol,
Calcium,
Calcium carbonate,
Carbonate ion		3件: D00129 ,
D00932 ,
D10802 		1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬1件: 235
67Other: Serum calcium concentrations results1件: Calcium---1件: 235
68Other: Standard treatment according to the Clinical protocols----3件: 49, 51, 235
69Other: Symptomatic hypocalcaemia at 24 hour----1件: 235
70Other: Symptomatic hypocalcaemia at 6 hour----1件: 235
71Palopegteriparatide----1件: 235
72Parathyroid hormon 1-84----1件: 235
73Parathyroid hormone1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬2件: 70, 235
74Parathyroid Hormone (1-84) Human Recombinant1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
75Parathyroid Hormone (rDNA)1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
76Parathyroideahormon----1件: 235
77PCO371----1件: 235
78Phosphate1件: Phosphate ion---33件: 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
79Phosphate and betamethasone acetate, 2 mL.3件: Acetate,
Betamethasone,
Phosphate ion		7件: D00244 ,
D00972 ,
D01357 ,
D01402 ,
D01637 ,
D02032 ,
D02286 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 235
80POLY(OXY-1,2-ETHANEDIYL), A----1件: 235
81POLY(OXY-1,2-ETHANEDIYL), ALPHA-HYDRO-OMEGA-METHOXY, ETHER WITH N-[[[2-1件: Diethyl ether1件: D01772 --1件: 235
82POLY(OXY-1,2-ETHANEDIYL), ALPHA-HYDRO-OMEGA-METHOXY, ETHER WITH N-[[[2-[[6-[[1-[3-[[3-(2,3-DIHYDROXYPROPOXY)PROPYL]AMINO]-3-OXOPROPYL]-2,5-DI1件: Diethyl ether1件: D01772 --1件: 235
83POLY(OXY-1,2-ETHANEDIYL), ALPHA-HYDRO-OMEGA-METHOXY, ETHER WITH N-[[[2-[[6-[[1-[3-[[3-(2,3-DIHYDROXYPROPOXY)PROPYL]AMINO]-3-OXOPROPYL]-2,5-DIOXO-3-PYRROLIDINYL]THIO]HEXYL]AMINO]ETHYL]AMINO]CARBONYL]-2-METHYLALANYL-TERIPARATIDE (2:1)2件: Diethyl ether,
Teriparatide		2件: D01772 ,
D06078 		1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
84Polyethylene glycol1件: Polyethylene glycol1件: D03370 --7件: 6, 78, 96, 97, 235, 276, 299
85Potassium1件: Potassium1件: D08403 --12件: 36, 46, 66, 67, 88, 94, 98, 115, 167, 179, 215, 235
86Potassium sparing diuretic1件: Potassium1件: D08403 --1件: 235
87PREOTACT1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
88PTH----2件: 65, 235
89PTH 1-341件: Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬2件: 65, 235
90PTH1-84 in parent study----1件: 235
91Rcombinant Human Parathyroid Hormone [rhPTH(1-84)]1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
92RECOMBINANT HUMAN PARATHYROID HORMONE (1-84)1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
93Recombinant Human Parathyroid Hormone [rhPTH(1-84)]1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
94RhPTH1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬3件: 70, 235, 326
95RhPTH (1-84)1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
96RhPTH(1-84)1件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
97Saline 0.9% NaCl----1件: 235
98Sevelamer1件: Sevelamer3件: D01983 ,
D06642 ,
D08512 		--2件: 235, 238
99Sodium citrate1件: Sodium citrate2件: D01781 ,
D05855 		--4件: 67, 214, 215, 235
100SUB21634----1件: 235
101Synthetic Human Parathyroid Hormone 1-341件: Parathyroid hormone1件: D05364 2件: PTH1R,
PTH2R 💬		3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
102Te----1件: 235
103Teriparatide1件: Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬6件: 46, 68, 70, 71, 235, 274
104Teriparatide conjugated to a multiarm polyethylene glycol carrier molecule through a cleava2件: Polyethylene glycol,
Teriparatide		2件: D03370 ,
D06078 		1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
105Teriparatide conjugated to a multiarm polyethylene glycol carrier molecule through a cleavable linker2件: Polyethylene glycol,
Teriparatide		2件: D03370 ,
D06078 		1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 235
106Thiazide----1件: 235
107Thymus/Parathyroid Transplantation----2件: 65, 235
108Total thyroidectomy----1件: 235
109TransCon PTH----1件: 235
110TransCon PTH high-dose pen----1件: 235
111TransCon PTH low-dose pen----1件: 235
112TransCon PTH mid-dose pen----1件: 235
113Tériparatide----1件: 235
114UN-ALPHA-R----1件: 235
115UN-ALPHA-R 0.25µg----1件: 235
116Verde de Indocianina (Indocyanine Green)1件: Indocyanine green1件: D01342 --1件: 235
117Vitamin D1件: Vitamin D---24件: 3, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299