230. Alveolar hypoventilation syndrome Clinical trials / Disease details

Clinical trials : 8 / Drugs : 11 - (DrugBank : 5) / Drug target genes : 18 - Drug target pathways : 28

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04108819 (ClinicalTrials.gov)	October 30, 2019	26/9/2019	Ketogenic Diet for Obesity Hypoventilation Syndrome	Ketogenic Diet for Obesity Hypoventilation Syndrome	Obesity Hypoventilation Syndrome;Ketogenic Dieting;Hypercapnic Respiratory Failure	Dietary Supplement: Ketogenic Diet	Johns Hopkins University	NULL	Recruiting	18 Years	75 Years	All	25	N/A	United States
2	NCT01964339 (ClinicalTrials.gov)	October 9, 2013	14/10/2013	Obesity Hypoventilation Syndrome Prevalence Study	Obesity Hypoventilation Syndrome Prevalence Study	Obesity Hypoventilation Syndrome	Other: BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (venous blood gas and metabolic panel) and data collection from PSG study.;Other: BMI greater than or equal to 30kg/m2 scheduled for PSG. Undergo blood draw (arterial blood gas and metabolic panel) and data collection from PSG study.	Philips Respironics	NULL	Terminated	21 Years	N/A	All	44		United States
3	NCT01500473 (ClinicalTrials.gov)	February 2012	22/12/2011	Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome	Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome	Congenital Central Hypoventilation Syndrome	Drug: Desogestrel	Children's Hospital Los Angeles	NULL	Not yet recruiting	16 Years	50 Years	Female	8	N/A	United States
4	NCT01499485 (ClinicalTrials.gov)	November 2011	20/12/2011	Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation.	Effects of Acetazolamide on the Duration of Mechanical Ventilation in Patients With Metabolic Alkalosis. Phase III Multicenter Double-blinded Clinical Trial.	Pulmonary Disease, Chronic Obstructive;Obesity Hypoventilation Syndrome;Metabolic Alkalosis	Drug: Acetazolamide;Drug: Placebo	Hospital Son Llatzer	NULL	Completed	18 Years	N/A	Both	140	Phase 3	Spain
5	NCT01243697 (ClinicalTrials.gov)	April 2011	17/11/2010	Assessment of Desogestrel in Ondine Syndrome	Assessment of Desogestrel for a Pharmacological Recovery of Ventilatory Activity in Congenital Central Hypoventilation Syndrome - Ondine Syndrome	Ondine Syndrome	Drug: desogestrel	Assistance Publique - Hôpitaux de Paris	NULL	Completed	10 Years	60 Years	Female	6	Phase 2/Phase 3	France
6	ChiCTR-DDT-11001215	2010-07-01	2011-03-05	Double position CT investigation of OSAHS	Double position CT investigation of OSAHS	Obstructive sleep apnea hypoventilation syndrome	Gold Standard:;Index test:;	First Hospital of Peking university	NULL	Completed			Both	Target condition:0;Difficult condition:0		China
7	EUCTR2005-005950-33-SE (EUCTR)	07/06/2006	10/04/2006	Studie av Domperidon och barn med kongenitalt centralt hypoventilationssyndrom. - DOMPCCHSSWE1	Studie av Domperidon och barn med kongenitalt centralt hypoventilationssyndrom. - DOMPCCHSSWE1	Congenital central hypoventilation syndrome, CCHS or Ondine's curse.	Trade Name: Motilium Product Name: Motilium INN or Proposed INN: Domperidone	Karolinska Universitetssjukhuset	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Sweden
8	EUCTR2011-000989-35-FR (EUCTR)		06/05/2011	N/A	N/A - RESPIRONDINE	MedDRA version: 14.0;Level: PT;Classification code 10066131;Term: Congenital central hypoventilation syndrome;System Organ Class: 10010331 - Congenital, familial and genetic disorders	Trade Name: Cerazette Product Name: Cerazette INN or Proposed INN: Désogestrel	ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)	NULL	NA			Female: yes Male: no		Phase 2	France