Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank Disease ID
1 Alcoholism 💬
[1] DRD2 💬 D01745 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
2 Alcoholism 💬
[1] DRD2 💬 D07868 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
3 Bile secretion 💬
[1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
4 Bile secretion 💬
[1] CA2 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
5 Breast cancer 💬
[2] ESR1, PGR 💬 D02367 💬 Desogestrel [1] 230 💬
6 cAMP signaling pathway 💬
[1] DRD2 💬 D01745 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
7 cAMP signaling pathway 💬
[1] DRD2 💬 D07868 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
8 Carbohydrate digestion and absorption 💬
[2] TAS1R2, TAS1R3 💬 D02381 💬 Aspartame [5]  6 , 13, 67, 86, 230 💬
9 Chemical carcinogenesis - receptor activation 💬
[2] ESR1, PGR 💬 D02367 💬 Desogestrel [1] 230 💬
10 Cocaine addiction 💬
[1] DRD2 💬 D01745 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
11 Cocaine addiction 💬
[1] DRD2 💬 D07868 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
12 Collecting duct acid secretion 💬
[1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
13 Collecting duct acid secretion 💬
[1] CA2 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
14 Dopaminergic synapse 💬
[1] DRD2 💬 D01745 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
15 Dopaminergic synapse 💬
[1] DRD2 💬 D07868 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
16 Endocrine and other factor-regulated calcium reabsorption 💬
[1] ESR1 💬 D02367 💬 Desogestrel [1] 230 💬
17 Endocrine resistance 💬
[1] ESR1 💬 D02367 💬 Desogestrel [1] 230 💬
18 Estrogen signaling pathway 💬
[2] ESR1, PGR 💬 D02367 💬 Desogestrel [1] 230 💬
19 Gap junction 💬
[1] DRD2 💬 D01745 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
20 Gap junction 💬
[1] DRD2 💬 D07868 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
21 Gastric acid secretion 💬
[1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
22 Gastric acid secretion 💬
[1] CA2 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
23 Metabolic pathways 💬
[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
24 Metabolic pathways 💬
[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
25 Neuroactive ligand-receptor interaction 💬
[1] DRD2 💬 D01745 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
26 Neuroactive ligand-receptor interaction 💬
[1] DRD2 💬 D07868 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
27 Nitrogen metabolism 💬
[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
28 Nitrogen metabolism 💬
[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
29 Oocyte meiosis 💬
[1] PGR 💬 D02367 💬 Desogestrel [1] 230 💬
30 Pancreatic secretion 💬
[1] CA2 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
31 Pancreatic secretion 💬
[1] CA2 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
32 Parkinson disease 💬
[1] DRD2 💬 D01745 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
33 Parkinson disease 💬
[1] DRD2 💬 D07868 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
34 Pathways in cancer 💬
[1] ESR1 💬 D02367 💬 Desogestrel [1] 230 💬
35 Progesterone-mediated oocyte maturation 💬
[1] PGR 💬 D02367 💬 Desogestrel [1] 230 💬
36 Prolactin signaling pathway 💬
[1] ESR1 💬 D02367 💬 Desogestrel [1] 230 💬
37 Proteoglycans in cancer 💬
[1] ESR1 💬 D02367 💬 Desogestrel [1] 230 💬
38 Proximal tubule bicarbonate reclamation 💬
[2] CA2, CA4 💬 D00218 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
39 Proximal tubule bicarbonate reclamation 💬
[2] CA2, CA4 💬 D01196 💬 Acetazolamide [8] 13, 86, 90, 115, 154, 155, 225, 230 💬
40 Rap1 signaling pathway 💬
[1] DRD2 💬 D01745 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
41 Rap1 signaling pathway 💬
[1] DRD2 💬 D07868 💬 Domperidone [5]  6 , 13, 17, 51, 230 💬
42 Taste transduction 💬
[2] TAS1R2, TAS1R3 💬 D02381 💬 Aspartame [5]  6 , 13, 67, 86, 230 💬
43 Thyroid hormone signaling pathway 💬
[1] ESR1 💬 D02367 💬 Desogestrel [1] 230 💬