86. Pulmonary arterial hypertension Clinical trials / Disease details

Clinical trials : 1,181 / Drugs : 701 - (DrugBank : 126) / Drug target genes : 105 - Drug target pathways : 192

6 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02507011 (ClinicalTrials.gov)	January 31, 2016	22/7/2015	Beta-blockers in Pulmonary Arterial Hypertension	Beta-blockers in Pulmonary Arterial Hypertension - A Phase 2 Double-Blind, Placebo-Controlled, Crossover Study Evaluating the Efficacy, and Safety of Carvedilol for Right Ventricular Dysfunction in Pulmonary Arterial Hypertension	Pulmonary Arterial Hypertension	Drug: Carvedilol;Drug: Placebo	University of Minnesota	NULL	Terminated	18 Years	N/A	All	2	Phase 2	United States
2	NCT02120339 (ClinicalTrials.gov)	May 2014	17/4/2014	Carvedilol PAH A Pilot Study of Efficacy and Safety	Beta Blockers in Pulmonary Arterial Hypertension (PAH) A Pilot Study of Efficacy and Safety	Pulmonary Hypertension;Cardiac MRI <40	Drug: Carvedilol	University of Minnesota	NULL	Terminated	18 Years	99 Years	All	5	Phase 1	United States
3	NCT01586156 (ClinicalTrials.gov)	December 2012	23/4/2012	PAHTCH Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure (Carvedilol)	Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure	Pulmonary Hypertension	Drug: Carvedilol;Drug: placebo	The Cleveland Clinic	National Institutes of Health (NIH);National Heart, Lung, and Blood Institute (NHLBI)	Completed	18 Years	65 Years	All	30	N/A	United States
4	NCT01723371 (ClinicalTrials.gov)	September 2012	31/10/2012	Beta Blockers for Treatment of Pulmonary Arterial Hypertension in Children	Beta Blockers for Treatment of Pulmonary Arterial Hypertension in Children	Pulmonary Arterial Hypertension	Drug: Carvedilol	The Hospital for Sick Children	NULL	Withdrawn	8 Years	17 Years	Both	0	Phase 1/Phase 2	Canada
5	NCT00964678 (ClinicalTrials.gov)	June 2010	24/8/2009	Pilot Study of the Safety and Efficacy of Carvedilol in Pulmonary Arterial Hypertension	Pilot Study of the Safety and Efficacy of Carvedilol in Pulmonary Arterial Hypertension	Pulmonary Arterial Hypertension	Drug: Carvedilol	Virginia Commonwealth University	GlaxoSmithKline	Completed	18 Years	N/A	All	10	Phase 1/Phase 2	United States
6	NCT00240656 (ClinicalTrials.gov)	October 2005	17/10/2005	Spironolactone Combined With Captopril and Carvedilol for the Treatment of Pulmonary Arterial Hypertension	Official Title: Spironolactone Combined With Captopril and Carvedilol for the Treatment of Patients With Pulmonary Arterial Hypertension Associated With Congenital Heart Disease—Focus on Pulmonary Artery Remodeling	Hypertension, Pulmonary	Drug: spironolactone captopril carvedilol	Hebei Medical University	NULL	Completed	N/A	80 Years	Both		Phase 1	China