Calcium Carbonate ( DrugBank: Calcium, Calcium carbonate, Carbonate )

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8 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
13	多発性硬化症／視神経脊髄炎	1
19	ライソゾーム病	1
46	悪性関節リウマチ	1
53	シェーグレン症候群	1
75	クッシング病	1
96	クローン病	1
235	副甲状腺機能低下症	5
299	嚢胞性線維症	1

13. 多発性硬化症／視神経脊髄炎

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臨床試験数 : 3,342 /  薬物数 : 2,355 - (DrugBank : 406) / 標的遺伝子数 : 269 - 標的パスウェイ数 : 241

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00785473 (ClinicalTrials.gov)	January 2008	4/11/2008	Can Vitamin D Supplementation Prevent Bone Loss in Persons With Multiple Sclerosis	Can Vitamin D Supplementation Prevent Bone Loss in Persons With MS? A Randomised, Placebo-controlled, Single-centre Study	Multiple Sclerosis, Osteoporosis	Dietary Supplement: cholecalciferol;Dietary Supplement: calcium carbonate	University Hospital of North Norway	NULL	Completed	18 Years	50 Years	Both	80	Phase 4	Norway

19. ライソゾーム病

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臨床試験数 : 854 /  薬物数 : 716 - (DrugBank : 105) / 標的遺伝子数 : 70 - 標的パスウェイ数 : 191

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00004488 (ClinicalTrials.gov)	October 1998	18/10/1999	Phase II Randomized Study of Alendronate Sodium for Osteopenia in Patients With Gaucher's Disease		Gaucher's Disease;Osteopenia	Drug: alendronate sodium;Drug: calcium carbonate;Drug: cholecalciferol	Children's Hospital Medical Center, Cincinnati	NULL	Completed	18 Years	50 Years	Both	82	Phase 2	United States;Israel

46. 悪性関節リウマチ

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臨床試験数 : 4,325 /  薬物数 : 2,671 - (DrugBank : 417) / 標的遺伝子数 : 187 - 標的パスウェイ数 : 224

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00000429 (ClinicalTrials.gov)	June 1996	18/1/2000	Calcium Supplements for Bone Health in Juvenile Rheumatoid Arthritis	Calcium Supplementation for Bone Mineralization in Juvenile Rheumatoid Arthritis (JRA)	Juvenile Rheumatoid Arthritis	Drug: Calcium carbonate	Children's Hospital Medical Center, Cincinnati	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	Completed	6 Years	18 Years	Both	192	Phase 2	United States

53. シェーグレン症候群

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臨床試験数 : 283 /  薬物数 : 320 - (DrugBank : 101) / 標的遺伝子数 : 56 - 標的パスウェイ数 : 181

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02370550 (ClinicalTrials.gov)	March 2015	18/2/2015	Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome	Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome(CTRIPS): A Prospective, Randomized, Multicenter, Double-Blind Placebo-Controlled Trial	Sjogren's Syndrome	Drug: Cyclosporin A;Drug: Prednisone;Drug: Placebo;Drug: Calcium carbonate D	Peking University People's Hospital	NULL	Recruiting	18 Years	75 Years	All	240	Phase 4	China

75. クッシング病

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臨床試験数 : 203 /  薬物数 : 191 - (DrugBank : 51) / 標的遺伝子数 : 62 - 標的パスウェイ数 : 128

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2008-002280-14-FR (EUCTR)	18/07/2008	06/06/2008	Comparative study of the effect of 4-week treatment with ossein-hydroxyapatite compound versus calcium carbonate on bone biomarkers in young women with low calcium intake. Prospective, monocenter, randomized, open-label, two-period,cross-over trial	Comparative study of the effect of 4-week treatment with ossein-hydroxyapatite compound versus calcium carbonate on bone biomarkers in young women with low calcium intake. Prospective, monocenter, randomized, open-label, two-period,cross-over trial	The Active substance of Osteopor is Ossein Hydroxyapatite.Treatment of processes characterized by decalcification: osteoporosis, Cushing syndrome, thyrotoxicosis. MedDRA version: 9.1;Level: LLT;Classification code 10006956;Term: Calcium deficiency	Trade Name: OSTEOPOR Product Name: OSTEOPOR Product Code: L0006CP03A INN or Proposed INN: ossein hydroxyapatite Trade Name: OROCAL Product Name: OROCAL INN or Proposed INN: calcium carbonate	Pierre Fabre Médicament	NULL	Not Recruiting			Female: yes Male: no	60	Phase 3	France

96. クローン病

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臨床試験数 : 2,400 /  薬物数 : 1,391 - (DrugBank : 267) / 標的遺伝子数 : 170 - 標的パスウェイ数 : 215

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01735461 (ClinicalTrials.gov)	December 2012	22/11/2012	Calcium Supplements Strategy for Kidney Stones Prevention in Crohn's Patients	Oral Calcium Supplementation, a Strategy to Reduce Kidney Stones in Crohn's Patients Living With a Small Bowel Resection	Kidney Calculi;Crohn's Disease	Dietary Supplement: Calcium Carbonate	University of British Columbia	University of Texas Southwestern Medical Center	Recruiting	19 Years	N/A	All	40	N/A	Canada

235. 副甲状腺機能低下症

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臨床試験数 : 88 /  薬物数 : 128 - (DrugBank : 25) / 標的遺伝子数 : 5 - 標的パスウェイ数 : 7

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03425747 (ClinicalTrials.gov)	October 15, 2019	27/1/2018	Efficacy of Calcium Citrate Versus Calcium Carbonate for the Management of Chronic Hypoparathyroidism	CALCIUM CITRATE vs CALCIUM CARBONATE FOR THE MANAGEMENT OF CHRONIC HYPOPARATHYROIDISM	Chronic Hypoparathyroidism	Drug: Calcium Carbonate;Drug: Calcium Citrate	Campus Bio-Medico University	NULL	Completed	18 Years	75 Years	All	26	Phase 4	Italy
2	NCT03249012 (ClinicalTrials.gov)	September 1, 2017	9/8/2017	Quality of Life Related to Different Treatment Protocols for Post-thyroidectomy Hypoparathyroidism	Comparing the Quality of Life Associated With Empiric Calcium Repletion and Parathormone (PTH) Based Calcium Repletion for Post Thyroidectomy Hypoparathyroidism	Hypoparathyroidism Postprocedural;Quality of Life	Other: Empiric use of Calcium Carbonate and Calcitriol;Other: PTH based Calcium Carbonate and Calcitriol repletion	CHU de Quebec-Universite Laval	NULL	Recruiting	18 Years	N/A	All	120	N/A	Canada
3	NCT04146259 (ClinicalTrials.gov)	January 1, 2017	29/10/2019	Changes in Circulating Sclerostin Levels During Acute Postsurgical Hypoparathyroidism	Changes in Circulating Sclerostin Levels During Acute Postsurgical Hypoparathyroidism	Hypoparathyroidism Postprocedural	Drug: calcium carbonate and alphacalcidol	University of Athens	NULL	Completed	19 Years	N/A	Female	109		Greece
4	NCT01815021 (ClinicalTrials.gov)	April 2013	7/3/2013	A Study Comparing Amorphous Calcium Carbonate (ACC) Versus Crystalline Calcium CCS) in Hypoparathyroidism Patients	A Randomized, Two Phase, Adaptive Then Crossover Open-label, Study Comparing Amorphous Calcium Carbonate (ACC) Supplement Versus Commercially Available Crystalline Calcium Supplements (CCS) in the Management of Primary Hypoparathyroidism.	Hypoparathyroidism	Dietary Supplement: amorphous calcium carbonate;Dietary Supplement: crystalline calcium supplements	Amorphical Ltd.	NULL	Completed	18 Years	80 Years	Both	10	Phase 1/Phase 2	Israel
5	JPRN-UMIN000000475	2006/07/01	01/09/2006	Therapeutic strategy of relative hypoparathyroidism in hemodialysis patients using sevelamer hydrochloride, with special reference to vitamin D administration		Relative hypoparathyoidism in maintenance hemodialysis patients	Replacement of calcium carbonate with sevelamer hydrochloride as phosphate binder	Hokusetsu ROD Study Group	NULL	Complete: follow-up complete	20years-old	Not applicable	Male and Female	40	Not applicable	Japan

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299. 嚢胞性線維症

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臨床試験数 : 1,696 /  薬物数 : 1,644 - (DrugBank : 272) / 標的遺伝子数 : 96 - 標的パスウェイ数 : 170

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00004489 (ClinicalTrials.gov)	October 1998	18/10/1999	Randomized Study of Alendronate in Adult Patients With Cystic Fibrosis Related Osteoporosis		Osteoporosis;Cystic Fibrosis	Drug: alendronate sodium;Drug: calcium carbonate;Drug: cholecalciferol	University of North Carolina	NULL	Completed	18 Years	45 Years	Both	60	N/A	United States

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