Elotuzumab ( DrugBank: Elotuzumab )


2 diseases
IDDisease name (Link within this page)Number of trials
28Systemic amyloidosis1
300IgG4-related disease1

28. Systemic amyloidosis


Clinical trials : 261 Drugs : 276 - (DrugBank : 81) / Drug target genes : 68 - Drug target pathways : 178
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03252600
(ClinicalTrials.gov)
August 25, 201724/7/2017Lenalidomide, Dexamethasone, and Elotuzumab With or Without Cyclophosphamide in Treating Patients With Relapsed Primary AmyloidosisA Randomized Phase 2 Trial of Lenalidomide/ Dexamethasone/ Elotuzumab +/- Cyclophosphamide Followed by Lenalidomide/ Dexamethasone/Elotuzumab Maintenance as Second-Line Therapy for Patients With Relapsed AL AmyloidosisRecurrent Primary AmyloidosisDrug: Cyclophosphamide;Drug: Dexamethasone;Biological: Elotuzumab;Other: Laboratory Biomarker Analysis;Drug: Lenalidomide;Other: Pharmacological StudyBarbara Ann Karmanos Cancer InstituteNational Cancer Institute (NCI);Bristol-Myers Squibb;Multiple Myeloma Research ConsortiumActive, not recruiting18 YearsN/AAll53Phase 2United States

300. IgG4-related disease


Clinical trials : 36 Drugs : 49 - (DrugBank : 22) / Drug target genes : 16 - Drug target pathways : 98
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04918147
(ClinicalTrials.gov)
October 13, 20214/6/2021Elotuzumab in Immunoglobulin G4-Related Disease (IgG4-RD)Elotuzumab in Immunoglobulin G4-Related Disease (IgG4-RD)IgG4 Related Disease;IgG4-RDDrug: elotuzumab;Drug: placebo for elotuzumab;Drug: methylprednisolone;Drug: diphenhydramine;Drug: acetaminophen;Drug: famotidine;Drug: prednisoneNational Institute of Allergy and Infectious Diseases (NIAID)Autoimmunity Centers of Excellence;Bristol-Myers Squibb;Rho Federal Systems Division, Inc.Active, not recruiting18 Years70 YearsAll75Phase 2United States